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Cytochrome P450 3A4 Mefenamic acid Mefenamic acid Mefenamic acid PIS1M1 Mefenamic acid PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Mefenamic acid undergoes metabolism to give Mefenamic acid PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Mefenamic acid Mefenamic acid Mefenamic acid PIS1M1 Mefenamic acid PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 MefeA MefeA Me ac P Me ac P U E a B Heme Hepatocytes Kidney Liver Cytosol Mefenamic acid undergoes metabolism to give Mefenamic acid PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 MefeA MefeA Me ac P Me ac P U E a B