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Cytochrome P450 3A4 Metronidazole Metronidazole Metronidazole PIS1M1 Metronidazole PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Metronidazole undergoes metabolism to give Metronidazole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Metronidazole Metronidazole Metronidazole PIS1M1 Metronidazole PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Metroni Metroni Met PIS Met PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Metronidazole undergoes metabolism to give Metronidazole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Metroni Metroni Met PIS Met PIS U E a B