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Cytochrome P450 3A4 Netarsudil Netarsudil Netarsudil PIS1M1 Netarsudil PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Netarsudil undergoes metabolism to give Netarsudil PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Netarsudil Netarsudil Netarsudil PIS1M1 Netarsudil PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Netar Netar Net PIS Net PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Netarsudil undergoes metabolism to give Netarsudil PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Netar Netar Net PIS Net PIS U E a B