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Cytochrome P450 3A4 Nicorandil Nicorandil Nicorandil PIS1M1 Nicorandil PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Nicorandil undergoes metabolism to give Nicorandil PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Nicorandil Nicorandil Nicorandil PIS1M1 Nicorandil PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Nicor Nicor Nic PIS Nic PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Nicorandil undergoes metabolism to give Nicorandil PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Nicor Nicor Nic PIS Nic PIS U E a B