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Cytochrome P450 3A4 Paramethadione Paramethadione Paramethadione PIS1M1 Paramethadione PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Paramethadione undergoes metabolism to give Paramethadione PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Paramethadione Paramethadione Paramethadione PIS1M1 Paramethadione PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Paradio Paradio Par PIS Par PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Paramethadione undergoes metabolism to give Paramethadione PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Paradio Paradio Par PIS Par PIS U E a B