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Cytochrome P450 3A4 Phentolamine Phentolamine Phentolamine PIS1M1 Phentolamine PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Phentolamine undergoes metabolism to give Phentolamine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Phentolamine Phentolamine Phentolamine PIS1M1 Phentolamine PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Regitin Regitin Phe PIS Phe PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Phentolamine undergoes metabolism to give Phentolamine PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Regitin Regitin Phe PIS Phe PIS U E a B