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Cytochrome P450 3A4 Posaconazole Posaconazole Posaconazole PIS1M1 Posaconazole PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Posaconazole undergoes metabolism to give Posaconazole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Posaconazole Posaconazole Posaconazole PIS1M1 Posaconazole PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Posacon Posacon Pos PIS Pos PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Posaconazole undergoes metabolism to give Posaconazole PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Posacon Posacon Pos PIS Pos PIS U E a B