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Cytochrome P450 3A4 Rosuvastatin Rosuvastatin Rosuvastatin PIS1M1 Rosuvastatin PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Rosuvastatin undergoes metabolism to give Rosuvastatin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Rosuvastatin Rosuvastatin Rosuvastatin PIS1M1 Rosuvastatin PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 RosuVat RosuVat Ros PIS Ros PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Rosuvastatin undergoes metabolism to give Rosuvastatin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 RosuVat RosuVat Ros PIS Ros PIS U E a B