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Cytochrome P450 3A4 Secobarbital Secobarbital Secobarbital PIS1M1 Secobarbital PIS1M1 Urinary Excretion and/or Bile duct Excretion Heme Hepatocytes Kidney Liver Cytosol Secobarbital undergoes metabolism to give Secobarbital PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Secobarbital Secobarbital Secobarbital PIS1M1 Secobarbital PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP3A4 Seconal Seconal Sec PIS Sec PIS U E a B Heme Hepatocytes Kidney Liver Cytosol Secobarbital undergoes metabolism to give Secobarbital PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP3A4 Seconal Seconal Sec PIS Sec PIS U E a B