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Cytochrome P450 1A2 Solifenacin Solifenacin Solifenacin PIS1M1 Solifenacin PIS1M1 Heme Urinary Excretion and/or Bile duct Excretion Hepatocytes Kidney Liver Cytosol Solifenacin undergoes metabolism to give Solifenacin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP1A2 Solifenacin Solifenacin Solifenacin PIS1M1 Solifenacin PIS1M1 Urinary Excretion and/or Bile duct Excretion
CYP1A2 Solifen Solifen Sol PIS Sol PIS Heme U E a B Hepatocytes Kidney Liver Cytosol Solifenacin undergoes metabolism to give Solifenacin PIS1M1. Endoplasmic Reticulum Bile Ducts Blood Vessel Blood Vessel
Endoplasmic Reticulum CYP1A2 Solifen Solifen Sol PIS Sol PIS U E a B