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Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Metaxalone PIS2M1 Metaxalone Metaxalone Metaxalone PIS1M1 Metaxalone PIS2M1 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Metaxalone undergoes metabolism to give Metaxalone PIS1M1 and Metaxalone PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown CYP3A4 CYP3A4 Metaxalone PIS2M1 Metaxalone Metaxalone Metaxalone PIS1M1 Metaxalone PIS2M1 Urinary Excretion and/or Bile duct Excretion