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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Bifonazole PIS1M1 Bifonazole PIS1M2 Bifonazole Bifonazole Bifonazole PIS1M1 Bifonazole PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Bifonazole undergoes metabolism to give Bifonazole PIS1M1 and Bifonazole PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Bifonazole PIS1M1 Bifonazole PIS1M2 Bifonazole Bifonazole Bifonazole PIS1M1 Bifonazole PIS1M2 Urinary Excretion and/or Bile duct Excretion