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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Micronomicin PIS1M1 Micronomicin PIS1M2 Micronomicin Micronomicin Micronomicin PIS1M1 Micronomicin PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Micronomicin undergoes metabolism to give Micronomicin PIS1M1 and Micronomicin PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Micronomicin PIS1M1 Micronomicin PIS1M2 Micronomicin Micronomicin Micronomicin PIS1M1 Micronomicin PIS1M2 Urinary Excretion and/or Bile duct Excretion