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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Norgestrel PIS1M1 Norgestrel PIS1M2 Norgestrel Norgestrel Norgestrel PIS1M1 Norgestrel PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Norgestrel undergoes metabolism to give Norgestrel PIS1M1 and Norgestrel PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Norgestrel PIS1M1 Norgestrel PIS1M2 Norgestrel Norgestrel Norgestrel PIS1M1 Norgestrel PIS1M2 Urinary Excretion and/or Bile duct Excretion