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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Pentobarbital PIS1M1 Pentobarbital PIS1M2 Pentobarbital Pentobarbital Pentobarbital PIS1M1 Pentobarbital PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Pentobarbital undergoes metabolism to give Pentobarbital PIS1M1 and Pentobarbital PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Pentobarbital PIS1M1 Pentobarbital PIS1M2 Pentobarbital Pentobarbital Pentobarbital PIS1M1 Pentobarbital PIS1M2 Urinary Excretion and/or Bile duct Excretion