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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Ubrogepant PIS1M1 Ubrogepant PIS1M2 Ubrogepant Ubrogepant Ubrogepant PIS1M1 Ubrogepant PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Ubrogepant undergoes metabolism to give Ubrogepant PIS1M1 and Ubrogepant PIS1M2.
Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 Ubrogepant PIS1M1 Ubrogepant PIS1M2 Ubrogepant Ubrogepant Ubrogepant PIS1M1 Ubrogepant PIS1M2 Urinary Excretion and/or Bile duct Excretion