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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Phenacemide PIS2M1 Phenacemide PIS2M1 Phenacemide PIS1M1 Phenacemide PIS1M1 Phenacemide Phenacemide Phenacemide PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Phenacemide undergoes metabolism to give Phenacemide PIS1M1, Phenacemide PIS1M2 and Phenacemide PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Phenacemide PIS2M1 Phenacemide PIS2M1 Phenacemide PIS1M1 Phenacemide PIS1M1 Phenacemide Phenacemide Phenacemide PIS1M2 Urinary Excretion and/or Bile duct Excretion