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Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Prazosin PIS2M1 Prazosin PIS2M1 Prazosin PIS1M1 Prazosin PIS1M1 Prazosin Prazosin Prazosin PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Prazosin undergoes metabolism to give Prazosin PIS1M1, Prazosin PIS1M2 and Prazosin PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Prazosin PIS2M1 Prazosin PIS2M1 Prazosin PIS1M1 Prazosin PIS1M1 Prazosin Prazosin Prazosin PIS1M2 Urinary Excretion and/or Bile duct Excretion