Loader
Loading Pathway...
Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Pretomanid PIS2M1 Pretomanid PIS2M1 Pretomanid PIS1M1 Pretomanid PIS1M1 Pretomanid Pretomanid Pretomanid PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Pretomanid undergoes metabolism to give Pretomanid PIS1M1, Pretomanid PIS1M2 and Pretomanid PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown CYP3A4 CYP3A4 CYP3A4 Pretomanid PIS2M1 Pretomanid PIS2M1 Pretomanid PIS1M1 Pretomanid PIS1M1 Pretomanid Pretomanid Pretomanid PIS1M2 Urinary Excretion and/or Bile duct Excretion