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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Udenafil Udenafil Udenafil PIS1M2 Udenafil PIS2M1 Udenafil PIS2M1 Udenafil PIS1M1 Udenafil PIS1M2 Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Udenafil undergoes metabolism to give Udenafil PIS1M1, Udenafil PIS1M2 and Udenafil PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 Udenafil Udenafil Udenafil PIS1M2 Udenafil PIS2M1 Udenafil PIS2M1 Udenafil PIS1M1 Udenafil PIS1M2 Urinary Excretion and/or Bile duct Excretion