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Unknown Unknown Unknown Unknown Cytochrome P450 1A2 Cytochrome P450 1A2 Cytochrome P450 1A2 Cytochrome P450 3A4 Miconazole Miconazole Miconazole PIS1M2 Miconazole PIS2M2 Miconazole PIS2M2 Miconazole PIS2M1 Miconazole PIS2M1 Miconazole PIS1M1 Miconazole PIS1M2 Heme Heme Urinary Excretion and/or Bile duct Excretion Heme Heme Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Miconazole undergoes metabolism to give Miconazole PIS1M1, Miconazole PIS1M2, Miconazole PIS1M3 and Miconazole PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown Unknown CYP1A2 CYP1A2 CYP1A2 CYP3A4 Miconazole Miconazole Miconazole PIS1M2 Miconazole PIS2M2 Miconazole PIS2M2 Miconazole PIS2M1 Miconazole PIS2M1 Miconazole PIS1M1 Miconazole PIS1M2 Urinary Excretion and/or Bile duct Excretion