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Unknown Unknown Unknown Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Cytochrome P450 3A4 Orciprenaline PIS1M1 Orciprenaline PIS1M1 Orciprenaline Orciprenaline Orciprenaline PIS1M2 Orciprenaline PIS2M1 Orciprenaline PIS2M1 Orciprenaline PIS1M2 Orciprenaline PIS1M3 Heme Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Endoplasmic Reticulum Liver Blood Vessel Kidney Bile Ducts Blood Vessel Orciprenaline undergoes metabolism to give Orciprenaline PIS1M1, Orciprenaline PIS1M2, Orciprenaline PIS1M3 and Orciprenaline PIS2M1.
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP3A4 CYP3A4 CYP3A4 CYP3A4 Orciprenaline PIS1M1 Orciprenaline PIS1M1 Orciprenaline Orciprenaline Orciprenaline PIS1M2 Orciprenaline PIS2M1 Orciprenaline PIS2M1 Orciprenaline PIS1M2 Orciprenaline PIS1M3 Urinary Excretion and/or Bile duct Excretion