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Unknown Unknown Unknown Cytochrome P450 1A2 Cytochrome P450 1A2 Cytochrome P450 3A4 Cytochrome P450 3A4 Iophendylate Iophendylate Iophendylate PIS2M2 Iophendylate PIS2M2 Iophendylate PIS2M1 Iophendylate PIS2M1 Iophendylate PIS1M1 Iophendylate PIS1M2 Heme Heme Heme Heme Urinary Excretion and/or Bile duct Excretion Endoplasmic Reticulum Cytosol Hepatocyte Blood Vessel Liver kidney Bile Duct Blood Vessel Iophendylate undergoes metabolism to give Iophendylate PIS1M1, Iophendylate PIS1M2, Iophendylate PIS1M3 and Iophendylate PIS2M1. Endoplasmic Reticulum
Endoplasmic Reticulum Endoplasmic Reticulum Unknown Unknown Unknown CYP1A2 CYP1A2 CYP3A4 CYP3A4 Iophendylate Iophendylate Iophendylate PIS2M2 Iophendylate PIS2M2 Iophendylate PIS2M1 Iophendylate PIS2M1 Iophendylate PIS1M1 Iophendylate PIS1M2 Urinary Excretion and/or Bile duct Excretion