The brain, eye, and kidney are some of the organs that have glucose as the sole metabolic fuel source. Prolonged fasting or vigorous exercise depletes glycogen stores, making the body switch to de-novo glucose synthesis to maintain blood levels of this monosaccharide. Gluconeogenesis is the process that allows the body to form glucose from non-hexose precursors, particularly glycerol, lactate, pyruvate, propionate, and glucogenic amino acids. [Melkonian EA, Asuka E, Schury MP. Physiology, Gluconeogenesis. 2023 Nov 13. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 31082163.]
References
Gluconeogenesis team 2 References
Melkonian EA, Asuka E, Schury MP: Physiology, Gluconeogenesis.
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