Carbon dioxide + Propionyl-CoA ↔ Methylmalonyl-CoA
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
3-methyl-2-oxobutanoate dehydrogenase (Lipoamide) E1-alpha chain
3-ketoacyl-CoA thiolase/acetyl-CoA acetyltransferase
Fatty acid oxidation complex alpha-subunit
L-Isoleucine + NAD + Water ↔ (3S)-3-Methyl-2-oxopentanoate + Ammonia + Hydrogen Ion + NADH
(3S)-3-Methyl-2-oxopentanoate + Thiamine pyrophosphate ↔ 2-Methyl-1-hydroxypropyl-ThPP + Carbon dioxide
2-Methyl-1-hydroxypropyl-ThPP + Lipoamide ↔ S-(2-Methylbutanoyl)-dihydrolipoamide + Thiamine pyrophosphate
Branched-chain-amino-acid aminotransferase
2-Methylacetoacetyl-CoA + Coenzyme A ↔ Acetyl-CoA + Propionyl-CoA
2-Methyl-3-hydroxybutyryl-CoA + NAD ↔ 2-Methylacetoacetyl-CoA + Hydrogen Ion + NADH
Tiglyl-CoA + Water ↔ 2-Methyl-3-hydroxybutyryl-CoA
(S)-2-Methylbutanoyl-CoA + Acceptor ↔ Reduced acceptor + Tiglyl-CoA
Coenzyme A + S-(2-Methylbutanoyl)-dihydrolipoamide ↔ (S)-2-Methylbutanoyl-CoA + Dihydrolipoamide