Pyocyanin biosynthesis involves a sequence of enzymatic activities that occur within the bacterial cell. The precursor molecule for pyocyanin production, chorismate, is produced from major metabolic pathways within the bacterial cell, such as phenylalanine, tyrosine, and tryptophan biosynthesis. These precursors are enzymatically transformed to pyocyanin by a sequence of processes facilitated by particular enzymes, including phenazine biosynthesis proteins (PhzE,D, and F). These enzymes promote the condensation, cyclization, and oxidation events essential for the synthesis of pyocyanin, which plays an important role in the virulence and pathogenicity.

Pyocyanine biosynthesis to be deleted References