PathWhiz

Pathway Description

Conversion of Succinate to Propanoate

Alistipes shahii WAL 8301

Metabolic Pathway

The enzymes involved in the decarboxylation of succinate to propionate are encoded in the Escherichia coli operon. A CoA transferase reaction is catalyzed by YgfH with succinyl CoA and propionyl CoA donating and succinate and propionate accepting. Sbm, sleeping beauty mutase or methylmalonyl-CoA mutase, is an apoenzyme that is activated by binding of adenosylcobalamin. Sbm catalyzes the methylmalonyl CoA mutase reaction. The metabolic function if this pathway is still unknown.

References

Conversion of Succinate to Propanoate References

This pathway was propagated using PathWhiz - Pon, A. et al. Pathways with PathWhiz (2015) Nucleic Acids Res. 43(Web Server issue): W552–W559.

Propagated from PW002058

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