Reference/TAXONOMY 411467
type: UnificationXref
id: 411467
db: TAXONOMY

Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

ReactionCatalysis672652
type: Catalysis
controller: chorismate mutase:tyrA
controlled: Reaction676584
control type: ACTIVATION

ReactionCatalysis672651
type: Catalysis
controller: chorismate mutase:tyrA
controlled: 5.4.99.5
control type: ACTIVATION

Reference/HMDB HMDB0001858
type: UnificationXref
id: HMDB0001858
db: HMDB

ReactionCatalysis672655
type: Catalysis
controller: Unknown
controlled: 4.1.99.19
control type: ACTIVATION

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

ReactionCatalysis672653
type: Catalysis
controller: tyrosine aminotransferase
controlled: 2.6.1.57
control type: ACTIVATION

Reference/ChemSpider 1001
type: UnificationXref
id: 1001
db: ChemSpider

Chorismate
type: SmallMolecule
cellular location: Cytosol
entity reference: Chorismate
name: SubPathwayOutput

Reference/HMDB HMDB0012199
type: UnificationXref
id: HMDB0012199
db: HMDB

ReactionCatalysis672657
type: Catalysis
controller: Unknown
controlled: Reaction676589
control type: ACTIVATION

Compound/PW C042640/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-iminoacetate
stoichiometric coefficient: 1.0

NADH
type: SmallMolecule
entity reference: NADH

Reference/BioCyc P-HYDROXY-PHENYLPYRUVATE
type: UnificationXref
id: P-HYDROXY-PHENYLPYRUVATE
db: BioCyc

Reference/HMDB HMDB0001983
type: UnificationXref
id: HMDB0001983
db: HMDB

Compound/PW C000103 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Tyrosine
stoichiometric coefficient: 1.0

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/PubChem-compound 30819
type: UnificationXref
id: 30819
db: PubChem-compound

L-Tyrosine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Tyrosine

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

Reference/HMDB HMDB0001185
type: UnificationXref
id: HMDB0001185
db: HMDB

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Chorismate Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway396320
pathway component: SubPathwayInteraction396320
xref: Reference/SMPDB SMP0000836
xref: Reference/PathWhiz PW000816
name: SubPathway

Reference/ChemSpider 5833
type: UnificationXref
id: 5833
db: ChemSpider

NAD
type: SmallMolecule
entity reference: NAD

Reference/PubChem-compound 6137
type: UnificationXref
id: 6137
db: PubChem-compound

ChemicalStructure/PW C002641
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC1=CC=C(OP(O)(O)=O)C=C1)C(O)=O

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000103
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC1=CC=C(O)C=C1)C(O)=O

Compound/PW C007748/Stoichiometry/1.0
type: Stoichiometry
physical entity: Chorismate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/ChemSpider 28593
type: UnificationXref
id: 28593
db: ChemSpider

S-Adenosylmethionine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 24762165
xref: Reference/KEGG Compound C00019
xref: Reference/ChemSpider 31983
xref: Reference/ChEBI CHEBI 15414
xref: Reference/CAS 485-80-3
xref: Reference/BioCyc S-ADENOSYLMETHIONINE
xref: Reference/HMDB HMDB0001185
chemical formula: C15H23N6O5S
molecular weight: 399.14505
structure: ChemicalStructure/PW C000921

Tyrosine Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/5695813
pathway order: PathwayEnzymeReaction/5695811
pathway order: PathwaySubPathway/396320
pathway order: PathwayTransport/5695814
pathway order: PathwayEnzymeReaction/5695809
pathway order: PathwayEnzymeReaction/5695808
pathway order: PathwayEnzymeReaction/5695807
pathway component: ReactionCatalysis672652
pathway component: ReactionCatalysis672651
pathway component: Chorismate Biosynthesis
pathway component: ReactionCatalysis672655
pathway component: ReactionCatalysis672653
pathway component: TransportCatalysis33562
pathway component: ReactionCatalysis672657
pathway component: 5.4.99.5
pathway component: Reaction676584
pathway component: 4.1.99.19
pathway component: 2.6.1.57
pathway component: Reaction676589
pathway component: Transport52284
xref: Reference/SMPDB SMP0392128
xref: Reference/PathWhiz PW401786
organism: Pseudoflavonifractor capillosus ATCC 29799

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/PubChem-compound 439182
type: UnificationXref
id: 439182
db: PubChem-compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/ChemSpider 954
type: UnificationXref
id: 954
db: ChemSpider

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

ChemicalStructure/PW C000548
type: ChemicalStructure
structure format: SMILES
structure data: CSCC[C@H](N)C(O)=O

ChemicalStructure/PW C007748
type: ChemicalStructure
structure format: SMILES

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Reference/BioCyc TYR
type: UnificationXref
id: TYR
db: BioCyc

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

ChemicalStructure/PW C000558
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C(=O)CC1=CC=C(O)C=C1

Reference/CAS 485-80-3
type: UnificationXref
id: 485-80-3
db: CAS

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChEBI CHEBI 17333
type: UnificationXref
id: CHEBI:17333
db: ChEBI

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

p-Cresol
type: SmallMolecule
entity reference: p-Cresol

Reference/PubChem-compound 1028
type: UnificationXref
id: 1028
db: PubChem-compound

p-Cresol
type: SmallMoleculeReference
xref: Reference/BioCyc CPD-108
xref: Reference/ChEBI CHEBI 17847
xref: Reference/PubChem-compound 2879
xref: Reference/ChemSpider 13839082
xref: Reference/HMDB HMDB0001858
xref: Reference/KEGG Compound C01468
xref: Reference/CAS 106-44-5
chemical formula: C7H8O
molecular weight: 108.05752
structure: ChemicalStructure/PW C001232

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Compound/PW C000558/Stoichiometry/1.0
type: Stoichiometry
physical entity: 4-Hydroxyphenylpyruvic acid
stoichiometric coefficient: 1.0

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

ChemicalStructure/PW C000921
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CH33ADO
type: UnificationXref
id: CH33ADO
db: BioCyc

chorismate mutase:tyrA
type: Complex
component stoichiometry: Protein/29303/Stoichiometry/2.0
component: Bifunctional chorismate mutase/prephenate dehydratase

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

tyrosine aminotransferase
type: Complex
component stoichiometry: Protein/29304/Stoichiometry/2.0
component: Unknown

5.4.99.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C007748/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
right: Prephenate
spontaneous: false
EC number: 5.4.99.5
left: Chorismate
name: Chorismate → Prephenate
conversion direction: LEFT_TO_RIGHT

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reaction676584
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007823/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
right: NADH
right: Carbon dioxide
right: 4-Hydroxyphenylpyruvic acid
spontaneous: false
left: Prephenate
left: NAD
name: NAD + Prephenate → 4-Hydroxyphenylpyruvic acid + Carbon dioxide + NADH
conversion direction: LEFT_TO_RIGHT

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/HMDB HMDB0000696
type: UnificationXref
id: HMDB0000696
db: HMDB

4.1.99.19
type: BiochemicalReaction
participant stoichiometry: Compound/PW C042640/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000921/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000548/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001232/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001329/Stoichiometry/1.0
right: p-Cresol
right: 2-iminoacetate
right: Hydrogen Ion
right: NADP
right: 5'-Deoxyadenosine
right: L-Methionine
spontaneous: false
EC number: 4.1.99.19
left: L-Tyrosine
left: NADPH
left: S-Adenosylmethionine
name: L-Tyrosine + NADPH + S-Adenosylmethionine → 2-iminoacetate + 5'-Deoxyadenosine + Hydrogen Ion + L-Methionine + NADP + p-Cresol
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Prephenate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16666
xref: Reference/CAS 126-49-8
xref: Reference/PubChem-compound 1028
xref: Reference/BioCyc PREPHENATE
xref: Reference/KEGG Compound C00254
xref: Reference/HMDB HMDB0012283
xref: Reference/ChemSpider 1001
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007823

Reference/PathWhiz PW401786
type: UnificationXref
id: PW401786
db: PathWhiz

Reference/BioCyc PREPHENATE
type: UnificationXref
id: PREPHENATE
db: BioCyc

2.6.1.57
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000558/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103/Stoichiometry/1.0
right: Oxoglutaric acid
right: L-Tyrosine
spontaneous: false
EC number: 2.6.1.57
left: L-Glutamic acid
left: 4-Hydroxyphenylpyruvic acid
name: 4-Hydroxyphenylpyruvic acid + L-Glutamic acid → L-Tyrosine + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reaction676589
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002641/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: L-Tyrosine
right: Phosphate
spontaneous: false
left: O-Phosphotyrosine
left: Water
name: O-Phosphotyrosine + Water → L-Tyrosine + Phosphate
conversion direction: LEFT_TO_RIGHT

Transport52284
type: Transport
participant stoichiometry: Compound/PW C000103 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000103 Periplasmic Space/Stoichiometry/1.0
right: L-Tyrosine
spontaneous: false
left: L-Tyrosine
name: L-Tyrosine (→) Transport: Pseudoflavonifractor capillosus ATCC 29799, Cytosol to Pseudoflavonifractor capillosus ATCC 29799, Periplasmic Space
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 388325
type: UnificationXref
id: 388325
db: ChemSpider

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/CAS 4754-39-6
type: UnificationXref
id: 4754-39-6
db: CAS

Reference/BioCyc CPD-108
type: UnificationXref
id: CPD-108
db: BioCyc

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/ChEBI CHEBI 15414
type: UnificationXref
id: CHEBI:15414
db: ChEBI

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000103 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Tyrosine
stoichiometric coefficient: 1.0

Compound/PW C001232/Stoichiometry/1.0
type: Stoichiometry
physical entity: p-Cresol
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 37788
type: UnificationXref
id: CHEBI:37788
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001232
type: ChemicalStructure
structure format: SMILES
structure data: CC1=CC=C(O)C=C1

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Protein/29303/Stoichiometry/2.0
type: Stoichiometry
physical entity: Bifunctional chorismate mutase/prephenate dehydratase
stoichiometric coefficient: 2.0

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/UniProt A6NZ62
type: UnificationXref
id: A6NZ62
db: UniProt

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Reference/KEGG Compound C00019
type: UnificationXref
id: C00019
db: KEGG Compound

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

L-Tyrosine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Tyrosine

Reference/KEGG Compound C00254
type: UnificationXref
id: C00254
db: KEGG Compound

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/BioCyc S-ADENOSYLMETHIONINE
type: UnificationXref
id: S-ADENOSYLMETHIONINE
db: BioCyc

Reference/KEGG Compound C00251
type: UnificationXref
id: C00251
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/KEGG Compound C01468
type: UnificationXref
id: C01468
db: KEGG Compound

Prephenate
type: SmallMolecule
entity reference: Prephenate

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Compound/PW C001329/Stoichiometry/1.0
type: Stoichiometry
physical entity: 5'-Deoxyadenosine
stoichiometric coefficient: 1.0

Pseudoflavonifractor capillosus ATCC 29799
type: BioSource
xref: Reference/TAXONOMY 411467

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/ChEBI CHEBI 15999
type: UnificationXref
id: CHEBI:15999
db: ChEBI

Reference/BioCyc MET
type: UnificationXref
id: MET
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

TransportCatalysis33562
type: Catalysis
controller: Lysine exporter LysO family protein
controlled: Transport52284
control type: ACTIVATION

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

ChemicalStructure/PW C001329
type: ChemicalStructure
structure format: SMILES

Compound/PW C000921/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Adenosylmethionine
stoichiometric coefficient: 1.0

Compound/PW C002641/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphotyrosine
stoichiometric coefficient: 1.0

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

ChemicalStructure/PW C042640
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C=N

Compound/PW C000103/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Tyrosine
stoichiometric coefficient: 1.0

L-Methionine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000696
xref: Reference/ChEBI CHEBI 16643
xref: Reference/KEGG Compound C00073
xref: Reference/CAS 63-68-3
xref: Reference/BioCyc MET
xref: Reference/PubChem-compound 6137
xref: Reference/ChemSpider 5907
chemical formula: C5H11NO2S
molecular weight: 149.05106
structure: ChemicalStructure/PW C000548

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/CAS 106-44-5
type: UnificationXref
id: 106-44-5
db: CAS

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

Water
type: SmallMolecule
entity reference: Water

Unknown
type: Protein
entity reference: Unknown

Lysine exporter LysO family protein
type: Protein
entity reference: Lysine exporter LysO family protein

Bifunctional chorismate mutase/prephenate dehydratase
type: Protein
entity reference: Bifunctional chorismate mutase/prephenate dehydratase

Reference/ChEBI CHEBI 16666
type: UnificationXref
id: CHEBI:16666
db: ChEBI

4-Hydroxyphenylpyruvic acid
type: SmallMoleculeReference
xref: Reference/BioCyc P-HYDROXY-PHENYLPYRUVATE
xref: Reference/CAS 156-39-8
xref: Reference/ChEBI CHEBI 15999
xref: Reference/PubChem-compound 979
xref: Reference/HMDB HMDB0000707
xref: Reference/ChemSpider 954
xref: Reference/KEGG Compound C01179
chemical formula: C9H8O4
molecular weight: 180.04225
structure: ChemicalStructure/PW C000558

2-iminoacetate
type: SmallMolecule
entity reference: 2-iminoacetate

Chorismate
type: SmallMoleculeReference
xref: Reference/CAS 617-12-9
xref: Reference/BioCyc CPD-9517
xref: Reference/KEGG Compound C00251
xref: Reference/PubChem-compound 12039
xref: Reference/ChEBI CHEBI 17333
xref: Reference/ChemSpider 11542
xref: Reference/HMDB HMDB0012199
chemical formula: C10H10O6
molecular weight: 226.04774
structure: ChemicalStructure/PW C007748

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/UniProt A6NXG7
type: UnificationXref
id: A6NXG7
db: UniProt

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Compound/PW C007823/Stoichiometry/1.0
type: Stoichiometry
physical entity: Prephenate
stoichiometric coefficient: 1.0

Reference/CAS 21820-51-9
type: UnificationXref
id: 21820-51-9
db: CAS

Reference/ChemSpider 11542
type: UnificationXref
id: 11542
db: ChemSpider

2-iminoacetate
type: SmallMoleculeReference
chemical formula: C2H3NO2
molecular weight: 73.01638
structure: ChemicalStructure/PW C042640

Reference/ChEBI CHEBI 17847
type: UnificationXref
id: CHEBI:17847
db: ChEBI

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/HMDB HMDB0000707
type: UnificationXref
id: HMDB0000707
db: HMDB

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

4-Hydroxyphenylpyruvic acid
type: SmallMolecule
entity reference: 4-Hydroxyphenylpyruvic acid

Chorismate
type: SmallMolecule
entity reference: Chorismate

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/KEGG Compound C05198
type: UnificationXref
id: C05198
db: KEGG Compound

Reference/CAS 617-12-9
type: UnificationXref
id: 617-12-9
db: CAS

Reference/HMDB HMDB0000158
type: UnificationXref
id: HMDB0000158
db: HMDB

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

Reference/CAS 63-68-3
type: UnificationXref
id: 63-68-3
db: CAS

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Reference/ChemSpider 5907
type: UnificationXref
id: 5907
db: ChemSpider

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

Reference/SMPDB SMP0000836
type: UnificationXref
id: SMP0000836
db: SMPDB

Reference/CAS 60-18-4
type: UnificationXref
id: 60-18-4
db: CAS

Reference/ChEBI CHEBI 16643
type: UnificationXref
id: CHEBI:16643
db: ChEBI

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

L-Methionine
type: SmallMolecule
entity reference: L-Methionine

Compound/PW C000548/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Methionine
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00073
type: UnificationXref
id: C00073
db: KEGG Compound

Reference/PubChem-compound 2879
type: UnificationXref
id: 2879
db: PubChem-compound

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/BioCyc CPD-9517
type: UnificationXref
id: CPD-9517
db: BioCyc

Reference/ChemSpider 31983
type: UnificationXref
id: 31983
db: ChemSpider

Reference/SMPDB SMP0392128
type: UnificationXref
id: SMP0392128
db: SMPDB

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

L-Tyrosine
type: SmallMoleculeReference
xref: Reference/CAS 60-18-4
xref: Reference/PubChem-compound 6057
xref: Reference/HMDB HMDB0000158
xref: Reference/ChEBI CHEBI 17895
xref: Reference/KEGG Compound C00082
xref: Reference/ChemSpider 5833
xref: Reference/BioCyc TYR
chemical formula: C9H11NO3
molecular weight: 181.0739
structure: ChemicalStructure/PW C000103

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/CAS 126-49-8
type: UnificationXref
id: 126-49-8
db: CAS

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

Reference/KEGG Compound C00082
type: UnificationXref
id: C00082
db: KEGG Compound

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/PathWhiz PW000816
type: UnificationXref
id: PW000816
db: PathWhiz

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/PubChem-compound 6057
type: UnificationXref
id: 6057
db: PubChem-compound

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 17319
type: UnificationXref
id: CHEBI:17319
db: ChEBI

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/HMDB HMDB0012283
type: UnificationXref
id: HMDB0012283
db: HMDB

Reference/KEGG Compound C06501
type: UnificationXref
id: C06501
db: KEGG Compound

5'-Deoxyadenosine
type: SmallMoleculeReference
xref: Reference/KEGG Compound C05198
xref: Reference/ChemSpider 388325
xref: Reference/CAS 4754-39-6
xref: Reference/HMDB HMDB0001983
xref: Reference/ChEBI CHEBI 17319
xref: Reference/BioCyc CH33ADO
xref: Reference/PubChem-compound 439182
chemical formula: C10H13N5O3
molecular weight: 251.10184
structure: ChemicalStructure/PW C001329

S-Adenosylmethionine
type: SmallMolecule
entity reference: S-Adenosylmethionine

Reference/KEGG Compound C01179
type: UnificationXref
id: C01179
db: KEGG Compound

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Lysine exporter LysO family protein
type: ProteinReference
xref: Reference/UniProt A6NZ62

Unknown
type: ProteinReference

Bifunctional chorismate mutase/prephenate dehydratase
type: ProteinReference
xref: Reference/UniProt A6NXG7

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

Reference/HMDB HMDB0006049
type: UnificationXref
id: HMDB0006049
db: HMDB

Reference/CAS 156-39-8
type: UnificationXref
id: 156-39-8
db: CAS

Protein/29304/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

5'-Deoxyadenosine
type: SmallMolecule
entity reference: 5'-Deoxyadenosine

SubPathwayInteraction396320
type: Interaction
name: SubPathwayReaction
name: SubPathway396320Reaction
participant: Chorismate

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

ChemicalStructure/PW C007823
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/ChEBI CHEBI 17895
type: UnificationXref
id: CHEBI:17895
db: ChEBI

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Reference/ChemSpider 13839082
type: UnificationXref
id: 13839082
db: ChemSpider

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

L-Tyrosine
type: SmallMolecule
entity reference: L-Tyrosine

Reference/PubChem-compound 12039
type: UnificationXref
id: 12039
db: PubChem-compound

Reference/PubChem-compound 24762165
type: UnificationXref
id: 24762165
db: PubChem-compound

O-Phosphotyrosine
type: SmallMolecule
entity reference: O-Phosphotyrosine

O-Phosphotyrosine
type: SmallMoleculeReference
xref: Reference/ChemSpider 28593
xref: Reference/CAS 21820-51-9
xref: Reference/HMDB HMDB0006049
xref: Reference/PubChem-compound 30819
xref: Reference/ChEBI CHEBI 37788
xref: Reference/KEGG Compound C06501
chemical formula: C9H12NO6P
molecular weight: 261.04022
structure: ChemicalStructure/PW C002641

Reference/PubChem-compound 979
type: UnificationXref
id: 979
db: PubChem-compound