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Efflux pump membrane transporter Putative azaleucine resistance protein AzlC Acetolactate synthase small subunit acetolactate synthase aminodeoxychorismate lyase Transcriptional regulator, GntR family Phosphogluconate dehydratase Pyruvic acid Pyruvic acid L-Valine L-Valine H+ CO2 (S)-2- Acetolactate H+ CO2 Isovaleric acid L-Glutamic acid Oxoglutaric acid H+ NADPH NADP (R)-2,3- Dihydroxy- isovalerate H2O Acetolactate synthase Acetolactate synthase Glycolysis and Pyruvate Dehydrogenase Cytoplasm Outer Membrane Gram-Negative Cell Periplasm Inner Membrane Plasmid