Reference/ChEBI CHEBI 16015
type: UnificationXref
id: CHEBI:16015
db: ChEBI

Reference/ChemSpider 30572
type: UnificationXref
id: 30572
db: ChemSpider

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/ChEBI CHEBI 15961
type: UnificationXref
id: CHEBI:15961
db: ChEBI

Reference/BioCyc O-PHOSPHO-L-HOMOSERINE
type: UnificationXref
id: O-PHOSPHO-L-HOMOSERINE
db: BioCyc

Oxalacetic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000223
xref: Reference/CAS 328-42-7
xref: Reference/ChEBI CHEBI 30744
xref: Reference/BioCyc OXALACETIC ACID
xref: Reference/ChemSpider 945
xref: Reference/PubChem-compound 970
xref: Reference/KEGG Compound C00036
chemical formula: C4H4O5
molecular weight: 132.00587
structure: ChemicalStructure/PW C000148

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/CAS 22138-53-0
type: UnificationXref
id: 22138-53-0
db: CAS

ChemicalStructure/PW C002747
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)[C@H](N)C(O)=O

NADH
type: SmallMolecule
entity reference: NADH

direct_interaction
type: InteractionVocabulary

ChemicalStructure/PW C000570
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCO)C(O)=O

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

O-Phosphohomoserine
type: SmallMolecule
cellular location: Cytosol
entity reference: O-Phosphohomoserine

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/ChemSpider 50
type: UnificationXref
id: 50
db: ChemSpider

SubPathwayInteraction407613
type: Interaction
name: SubPathway407613Reaction
name: SubPathwayReaction
participant: a [protein]-(L-serine/L-threonine)
participant: L-Threonine

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003484
type: UnificationXref
id: HMDB0003484
db: HMDB

SubPathwayInteraction407614
type: Interaction
name: SubPathway407614Reaction
name: SubPathwayReaction
participant: Oxalacetic acid

Reaction701325
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000095/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000148/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000134/Stoichiometry/1.0
right: L-Aspartic acid
right: Oxoglutaric acid
spontaneous: false
left: L-Glutamic acid
left: Oxalacetic acid
name: L-Glutamic acid + Oxalacetic acid → L-Aspartic acid + Oxoglutaric acid
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 809
type: UnificationXref
id: 809
db: ChemSpider

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/KEGG Compound C00441
type: UnificationXref
id: C00441
db: KEGG Compound

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc OXALACETIC ACID
type: UnificationXref
id: OXALACETIC_ACID
db: BioCyc

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/ChEBI CHEBI 17475
type: UnificationXref
id: CHEBI:17475
db: ChEBI

Compound/PW C000095/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Glutamic acid
stoichiometric coefficient: 1.0

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Compound/PW C001905/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphohomoserine
stoichiometric coefficient: 1.0

Reference/CAS 328-42-7
type: UnificationXref
id: 328-42-7
db: CAS

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Reference/PubChem-compound 51
type: UnificationXref
id: 51
db: PubChem-compound

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Reference/PubChem-compound 6288
type: UnificationXref
id: 6288
db: PubChem-compound

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Compound/Generic234 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: a [protein]-(L-serine/L-threonine) phosphate
stoichiometric coefficient: 1.0

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5745
type: UnificationXref
id: 5745
db: ChemSpider

Reference/BioCyc THR
type: UnificationXref
id: THR
db: BioCyc

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/BioCyc L-ASPARTATE
type: UnificationXref
id: L-ASPARTATE
db: BioCyc

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Oxoglutaric acid
type: SmallMoleculeReference
xref: Reference/CAS 328-50-7
xref: Reference/PubChem-compound 51
xref: Reference/BioCyc 2-KETOGLUTARATE
xref: Reference/HMDB HMDB0000208
xref: Reference/ChEBI CHEBI 30915
xref: Reference/KEGG Compound C00026
xref: Reference/ChemSpider 50
chemical formula: C5H6O5
molecular weight: 146.02153
structure: ChemicalStructure/PW C000134

Unknown
type: ProteinReference

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

O-Phosphohomoserine
type: SmallMoleculeReference
xref: Reference/PubChem-compound 151187
xref: Reference/CAS 4210-66-6
xref: Reference/ChEBI CHEBI 15961
xref: Reference/BioCyc O-PHOSPHO-L-HOMOSERINE
xref: Reference/ChemSpider 133252
xref: Reference/HMDB HMDB0003484
xref: Reference/KEGG Compound C01102
chemical formula: C4H10NO6P
molecular weight: 199.02457
structure: ChemicalStructure/PW C001905

Reference/PathWhiz PW410327
type: UnificationXref
id: PW410327
db: PathWhiz

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Oxalacetic acid
type: SmallMolecule
entity reference: Oxalacetic acid
name: SubPathwayOutput

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

NADPH
type: SmallMolecule
entity reference: NADPH

Reference/ChemSpider 945
type: UnificationXref
id: 945
db: ChemSpider

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Reference/SMPDB SMP0399367
type: UnificationXref
id: SMP0399367
db: SMPDB

Reference/PubChem-compound 440033
type: UnificationXref
id: 440033
db: PubChem-compound

NADP
type: SmallMolecule
entity reference: NADP

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

Reference/ChemSpider 90998
type: UnificationXref
id: 90998
db: ChemSpider

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/KEGG Compound C03508
type: UnificationXref
id: C03508
db: KEGG Compound

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Reference/BioCyc GLY
type: UnificationXref
id: GLY
db: BioCyc

Compound/PW C000414 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

ReactionCatalysis605615
type: Catalysis
controller: Aspartate kinase
controlled: 2.7.2.4
control type: ACTIVATION

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/ChEBI CHEBI 16857
type: UnificationXref
id: CHEBI:16857
db: ChEBI

Reference/HMDB HMDB0000208
type: UnificationXref
id: HMDB0000208
db: HMDB

Reference/CAS 672-15-1
type: UnificationXref
id: 672-15-1
db: CAS

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Reference/CAS 1068-84-4
type: UnificationXref
id: 1068-84-4
db: CAS

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

L-Glutamic acid
type: SmallMolecule
entity reference: L-Glutamic acid

Reference/CAS 72-19-5
type: UnificationXref
id: 72-19-5
db: CAS

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Reference/CAS 4210-66-6
type: UnificationXref
id: 4210-66-6
db: CAS

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Aminomalonic acid
type: SmallMolecule
entity reference: Aminomalonic acid

ChemicalStructure/PW C000134
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CCC(=O)C(O)=O

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Reference/ChEBI CHEBI 30915
type: UnificationXref
id: CHEBI:30915
db: ChEBI

Reference/PathWhiz PW000779
type: UnificationXref
id: PW000779
db: PathWhiz

Glycine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000123
xref: Reference/BioCyc GLY
xref: Reference/ChemSpider 730
xref: Reference/PubChem-compound 5257127
xref: Reference/CAS 56-40-6
xref: Reference/ChEBI CHEBI 15428
xref: Reference/KEGG Compound C00037
chemical formula: C2H5NO2
molecular weight: 75.03203
structure: ChemicalStructure/PW C000078

Reference/PubChem-compound 100714
type: UnificationXref
id: 100714
db: PubChem-compound

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

ChemicalStructure/PW C001905
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCOP(O)(O)=O)C(O)=O

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

TransportCatalysis31487
type: Catalysis
controller: Unknown
controlled: Transport50046
control type: ACTIVATION

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Reference/HMDB HMDB0000223
type: UnificationXref
id: HMDB0000223
db: HMDB

Reference/ChemSpider 6051
type: UnificationXref
id: 6051
db: ChemSpider

Reference/PubChem-compound 5257127
type: UnificationXref
id: 5257127
db: PubChem-compound

Reference/KEGG Compound C03082
type: UnificationXref
id: C03082
db: KEGG Compound

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc GLT
type: UnificationXref
id: GLT
db: BioCyc

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Compound/PW C000123/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartic acid
stoichiometric coefficient: 1.0

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/PubChem-compound 44367445
type: UnificationXref
id: 44367445
db: PubChem-compound

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway407614
pathway component: SubPathwayInteraction407614
xref: Reference/SMPDB SMP0000802
xref: Reference/PathWhiz PW000779
name: SubPathway

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

ReactionCatalysis748773
type: Catalysis
controller: aspartate semialdehyde dehydrogenase
controlled: Reaction747611
control type: ACTIVATION

ChemicalStructure/PW C000109
type: ChemicalStructure
structure format: SMILES
structure data: C[C@@H](O)[C@H](N)C(O)=O

Protein/29196/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/KEGG Compound C01102
type: UnificationXref
id: C01102
db: KEGG Compound

ReactionCatalysis748776
type: Catalysis
controller: homoserine kinase
controlled: 2.7.1.39
control type: ACTIVATION

ReactionCatalysis748778
type: Catalysis
controller: threonine dehydrogenase
controlled: 1.1.1.103
control type: ACTIVATION

Compound/PW C000570/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Homoserine
stoichiometric coefficient: 1.0

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Glycine
type: SmallMolecule
entity reference: Glycine

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Reference/HMDB HMDB0006454
type: UnificationXref
id: HMDB0006454
db: HMDB

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Threonine Biosynthesis
type: Pathway
pathway order: PathwayEnzymeReaction/5827073
pathway order: PathwayInteraction/7993
pathway order: PathwayEnzymeReaction/5827083
pathway order: PathwayEnzymeReaction/5827071
pathway order: PathwayEnzymeReaction/5827081
pathway order: PathwaySubPathway/407614
pathway order: PathwaySubPathway/407613
pathway order: PathwayEnzymeReaction/5827069
pathway order: PathwayTransport/5827085
pathway order: PathwayEnzymeReaction/5827068
pathway order: PathwayEnzymeReaction/5827079
pathway order: PathwayEnzymeReaction/5827077
pathway order: PathwayEnzymeReaction/5827075
pathway component: ReactionCatalysis699542
pathway component: Transport50046
pathway component: Reaction701325
pathway component: ReactionCatalysis699612
pathway component: ReactionCatalysis605615
pathway component: TCA Cycle
pathway component: ReactionCatalysis748780
pathway component: Protein Biosynthesis
pathway component: ReactionCatalysis748783
pathway component: ReactionCatalysis748773
pathway component: ReactionCatalysis748784
pathway component: Interaction7993
pathway component: TransportCatalysis31487
pathway component: ReactionCatalysis748776
pathway component: 2.7.2.4
pathway component: ReactionCatalysis748778
pathway component: 1.1.1.103
pathway component: 2.3.1.29
pathway component: 2.7.1.39
pathway component: 4.2.3.1
pathway component: Reaction747611
pathway component: 2.7.11.1
xref: Reference/PathWhiz PW410327
xref: Reference/SMPDB SMP0399367
organism: Succinatimonas hippei YIT 12066

Reference/ChemSpider 12126
type: UnificationXref
id: 12126
db: ChemSpider

ReactionCatalysis699542
type: Catalysis
controller: aspartate transaminase
controlled: Reaction701325
control type: ACTIVATION

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Protein Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway407613
pathway component: SubPathwayInteraction407613
name: SubPathway

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/KEGG Compound C00263
type: UnificationXref
id: C00263
db: KEGG Compound

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00026
type: UnificationXref
id: C00026
db: KEGG Compound

Reference/KEGG Compound C00025
type: UnificationXref
id: C00025
db: KEGG Compound

Compound/PW C007794/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartate-semialdehyde
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Reference/HMDB HMDB0000123
type: UnificationXref
id: HMDB0000123
db: HMDB

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

L-Threonine
type: SmallMolecule
cellular location: Cytosol
entity reference: L-Threonine

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine triphosphate

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

ChemicalStructure/PW C000123
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC(O)=O)C(O)=O

Succinatimonas hippei YIT 12066
type: BioSource
xref: Reference/TAXONOMY 762983

ChemicalStructure/PW C007794
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CC=O)C(O)=O

ChemicalStructure/PW C007795
type: ChemicalStructure
structure format: SMILES
structure data: NC(CC(=O)OP(O)(O)=O)C(O)=O

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Protein/Generic233 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: a [protein]-(L-serine/L-threonine)
stoichiometric coefficient: 1.0

2.7.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000570/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007794/Stoichiometry/1.0
right: L-Homoserine
right: NADP
spontaneous: false
EC number: 2.7.2.4
left: L-Aspartate-semialdehyde
left: Hydrogen Ion
left: NADPH
name: Hydrogen Ion + L-Aspartate-semialdehyde + NADPH → L-Homoserine + NADP
conversion direction: LEFT_TO_RIGHT

Reference/SMPDB SMP0000802
type: UnificationXref
id: SMP0000802
db: SMPDB

ReactionCatalysis699612
type: Catalysis
controller: aspartate kinase / homoserine dehydrogenase
controlled: 2.7.2.4
control type: ACTIVATION

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Compound/PW C000078/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycine
stoichiometric coefficient: 1.0

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00037
type: UnificationXref
id: C00037
db: KEGG Compound

Reference/KEGG Compound C00036
type: UnificationXref
id: C00036
db: KEGG Compound

Reference/ChemSpider 389046
type: UnificationXref
id: 389046
db: ChemSpider

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Reference/CAS 328-50-7
type: UnificationXref
id: 328-50-7
db: CAS

L-Homoserine
type: SmallMolecule
entity reference: L-Homoserine

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

homoserine kinase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

2-amino-3-ketobutyrate CoA ligase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

threonine dehydrogenase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/4.0
component: Unknown

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/HMDB HMDB0012249
type: UnificationXref
id: HMDB0012249
db: HMDB

Reference/ChEBI CHEBI 15699
type: UnificationXref
id: CHEBI:15699
db: ChEBI

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

L-2-Amino-3-oxobutanoic acid
type: SmallMolecule
entity reference: L-2-Amino-3-oxobutanoic acid

ReactionCatalysis748780
type: Catalysis
controller: 2-amino-3-ketobutyrate CoA ligase
controlled: 2.3.1.29
control type: ACTIVATION

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/KEGG Compound C00049
type: UnificationXref
id: C00049
db: KEGG Compound

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

ReactionCatalysis748783
type: Catalysis
controller: Unknown
controlled: 4.2.3.1
control type: ACTIVATION

ReactionCatalysis748784
type: Catalysis
controller: Unknown
controlled: 2.7.11.1
control type: ACTIVATION

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Adenosine diphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000148
type: UnificationXref
id: HMDB0000148
db: HMDB

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Compound/PW C002747/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-2-Amino-3-oxobutanoic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 12647
type: UnificationXref
id: 12647
db: PubChem-compound

ChemicalStructure/PW C000148
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)CC(=O)C(O)=O

Reference/HMDB HMDB0012250
type: UnificationXref
id: HMDB0012250
db: HMDB

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Protein/29196/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

Compound/PW C001034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

L-Threonine
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: L-Threonine

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/BioCyc L-BETA-ASPARTYL-P
type: UnificationXref
id: L-BETA-ASPARTYL-P
db: BioCyc

Reference/CAS 56-86-0
type: UnificationXref
id: 56-86-0
db: CAS

a [protein]-(L-serine/L-threonine) phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: a [protein]-(L-serine/L-threonine) phosphate

Aminomalonic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001147
xref: Reference/ChemSpider 90998
xref: Reference/PubChem-compound 100714
xref: Reference/ChEBI CHEBI 17475
xref: Reference/CAS 1068-84-4
xref: Reference/KEGG Compound C00872
chemical formula: C3H5NO4
molecular weight: 119.02186
structure: ChemicalStructure/PW C000893

L-Glutamic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 33032
xref: Reference/ChEBI CHEBI 16015
xref: Reference/ChemSpider 30572
xref: Reference/HMDB HMDB0000148
xref: Reference/CAS 56-86-0
xref: Reference/BioCyc GLT
xref: Reference/KEGG Compound C00025
chemical formula: C5H9NO4
molecular weight: 147.05316
structure: ChemicalStructure/PW C000095

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/PubChem-compound 33032
type: UnificationXref
id: 33032
db: PubChem-compound

a [protein]-(L-serine/L-threonine)
type: Protein
entity reference: a [protein]-(L-serine/L-threonine)
name: SubPathwayOutput

Reference/ChEBI CHEBI 40673
type: UnificationXref
id: CHEBI:40673
db: ChEBI

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/TAXONOMY 762983
type: UnificationXref
id: 762983
db: TAXONOMY

Reference/ChEBI CHEBI 17053
type: UnificationXref
id: CHEBI:17053
db: ChEBI

Reference/KEGG Compound C00188
type: UnificationXref
id: C00188
db: KEGG Compound

Reference/CAS 56-40-6
type: UnificationXref
id: 56-40-6
db: CAS

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

aspartate transaminase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

Compound/PW C000134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxoglutaric acid
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/HMDB HMDB0000719
type: UnificationXref
id: HMDB0000719
db: HMDB

Reference/HMDB HMDB0000167
type: UnificationXref
id: HMDB0000167
db: HMDB

Compound/PW C000109/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

Compound/PW C001905 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: O-Phosphohomoserine
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15428
type: UnificationXref
id: CHEBI:15428
db: ChEBI

Compound/PW C007795/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Aspartyl-4-phosphate
stoichiometric coefficient: 1.0

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/ChemSpider 133252
type: UnificationXref
id: 133252
db: ChemSpider

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Reference/PubChem-compound 151187
type: UnificationXref
id: 151187
db: PubChem-compound

L-Threonine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000167
xref: Reference/PubChem-compound 6288
xref: Reference/CAS 72-19-5
xref: Reference/ChemSpider 6051
xref: Reference/ChEBI CHEBI 16857
xref: Reference/KEGG Compound C00188
xref: Reference/BioCyc THR
chemical formula: C4H9NO3
molecular weight: 119.05824
structure: ChemicalStructure/PW C000109

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Compound/PW C000109 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0

Reference/BioCyc 2-KETOGLUTARATE
type: UnificationXref
id: 2-KETOGLUTARATE
db: BioCyc

O-Phosphohomoserine
type: SmallMolecule
entity reference: O-Phosphohomoserine

Unknown
type: Protein
entity reference: Unknown

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00872
type: UnificationXref
id: C00872
db: KEGG Compound

Reference/PubChem-compound 439235
type: UnificationXref
id: 439235
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/ChemSpider 730
type: UnificationXref
id: 730
db: ChemSpider

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/HMDB HMDB0001147
type: UnificationXref
id: HMDB0001147
db: HMDB

Oxoglutaric acid
type: SmallMolecule
entity reference: Oxoglutaric acid

ChemicalStructure/PW C000893
type: ChemicalStructure
structure format: SMILES
structure data: NC(C(O)=O)C(O)=O

ChemicalStructure/PW C000095
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CCC(O)=O)C(O)=O

Reference/CAS 15106-57-7
type: UnificationXref
id: 15106-57-7
db: CAS

4.2.3.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001905 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000109 Cytosol/Stoichiometry/1.0
right: Phosphate
right: L-Threonine
spontaneous: false
EC number: 4.2.3.1
left: O-Phosphohomoserine
left: Water
name: O-Phosphohomoserine + Water → L-Threonine + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

2.7.11.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/Generic234 Cytosol/Stoichiometry/1.0
participant stoichiometry: Protein/Generic233 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034 Cytosol/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: a [protein]-(L-serine/L-threonine) phosphate
spontaneous: false
EC number: 2.7.11.1
left: a [protein]-(L-serine/L-threonine)
left: Adenosine triphosphate
name: Adenosine triphosphate + a [protein]-(L-serine/L-threonine) → Adenosine diphosphate + Hydrogen Ion + a [protein]-(L-serine/L-threonine) phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/PubChem-compound 832
type: UnificationXref
id: 832
db: PubChem-compound

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

2.7.2.4
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000123/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007795/Stoichiometry/1.0
right: Adenosine diphosphate
right: L-Aspartyl-4-phosphate
spontaneous: false
EC number: 2.7.2.4
left: L-Aspartic acid
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Aspartic acid → Adenosine diphosphate + L-Aspartyl-4-phosphate
conversion direction: LEFT_TO_RIGHT

L-Aspartyl-4-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc L-BETA-ASPARTYL-P
xref: Reference/KEGG Compound C03082
xref: Reference/ChemSpider 809
xref: Reference/PubChem-compound 832
xref: Reference/CAS 22138-53-0
xref: Reference/HMDB HMDB0012250
chemical formula: C4H8NO7P
molecular weight: 213.00385
structure: ChemicalStructure/PW C007795

L-Aspartic acid
type: SmallMolecule
entity reference: L-Aspartic acid

1.1.1.103
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000109/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002747/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: L-2-Amino-3-oxobutanoic acid
spontaneous: false
EC number: 1.1.1.103
left: NAD
left: L-Threonine
name: L-Threonine + NAD → Hydrogen Ion + L-2-Amino-3-oxobutanoic acid + NADH
conversion direction: LEFT_TO_RIGHT

L-Aspartate-semialdehyde
type: SmallMolecule
entity reference: L-Aspartate-semialdehyde

Reference/ChEBI CHEBI 30744
type: UnificationXref
id: CHEBI:30744
db: ChEBI

L-Aspartyl-4-phosphate
type: SmallMolecule
entity reference: L-Aspartyl-4-phosphate

2.3.1.29
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000078/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C002747/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
right: Glycine
right: Acetyl-CoA
spontaneous: false
EC number: 2.3.1.29
left: Coenzyme A
left: L-2-Amino-3-oxobutanoic acid
name: Coenzyme A + L-2-Amino-3-oxobutanoic acid → Acetyl-CoA + Glycine
conversion direction: LEFT_TO_RIGHT

Reference/BioCyc AMINO-OXOBUT
type: UnificationXref
id: AMINO-OXOBUT
db: BioCyc

L-Aspartic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 44367445
xref: Reference/ChemSpider 5745
xref: Reference/ChEBI CHEBI 17053
xref: Reference/HMDB HMDB0000191
xref: Reference/CAS 56-84-8
xref: Reference/KEGG Compound C00049
xref: Reference/BioCyc L-ASPARTATE
chemical formula: C4H7NO4
molecular weight: 133.0375
structure: ChemicalStructure/PW C000123

2.7.1.39
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000570/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001905/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: O-Phosphohomoserine
spontaneous: false
EC number: 2.7.1.39
left: L-Homoserine
left: Adenosine triphosphate
name: Adenosine triphosphate + L-Homoserine → Adenosine diphosphate + Hydrogen Ion + O-Phosphohomoserine
conversion direction: LEFT_TO_RIGHT

L-Aspartate-semialdehyde
type: SmallMoleculeReference
xref: Reference/PubChem-compound 439235
xref: Reference/HMDB HMDB0012249
xref: Reference/ChEBI CHEBI 18051
xref: Reference/KEGG Compound C00441
xref: Reference/ChemSpider 388372
xref: Reference/CAS 15106-57-7
xref: Reference/BioCyc L-ASPARTATE-SEMIALDEHYDE
chemical formula: C4H7NO3
molecular weight: 117.042595
structure: ChemicalStructure/PW C007794

Reaction747611
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007795/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007794/Stoichiometry/1.0
right: NADP
right: L-Aspartate-semialdehyde
right: Phosphate
spontaneous: false
left: Hydrogen Ion
left: L-Aspartyl-4-phosphate
left: NADPH
name: Hydrogen Ion + L-Aspartyl-4-phosphate + NADPH → L-Aspartate-semialdehyde + NADP + Phosphate
conversion direction: LEFT_TO_RIGHT

Transport50046
type: Transport
participant stoichiometry: Compound/PW C000109 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000109 Cytosol/Stoichiometry/1.0
right: L-Threonine
right: Hydrogen Ion
spontaneous: false
left: Hydrogen Ion
left: L-Threonine
name: L-Threonine (→), Hydrogen Ion (→) Transport: Succinatimonas hippei YIT 12066, Periplasmic Space to Succinatimonas hippei YIT 12066, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/ChemSpider 388372
type: UnificationXref
id: 388372
db: ChemSpider

a [protein]-(L-serine/L-threonine)
type: ProteinReference
organism: Succinatimonas hippei YIT 12066

L-2-Amino-3-oxobutanoic acid
type: SmallMoleculeReference
xref: Reference/KEGG Compound C03508
xref: Reference/ChEBI CHEBI 40673
xref: Reference/PubChem-compound 440033
xref: Reference/HMDB HMDB0006454
xref: Reference/BioCyc AMINO-OXOBUT
xref: Reference/ChemSpider 389046
chemical formula: C4H7NO3
molecular weight: 117.042595
structure: ChemicalStructure/PW C002747

Reference/BioCyc L-ASPARTATE-SEMIALDEHYDE
type: UnificationXref
id: L-ASPARTATE-SEMIALDEHYDE
db: BioCyc

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/BioCyc HOMO-SER
type: UnificationXref
id: HOMO-SER
db: BioCyc

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Reference/ChEBI CHEBI 18051
type: UnificationXref
id: CHEBI:18051
db: ChEBI

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000078
type: ChemicalStructure
structure format: SMILES
structure data: NCC(O)=O

Reference/HMDB HMDB0000191
type: UnificationXref
id: HMDB0000191
db: HMDB

a [protein]-(L-serine/L-threonine) phosphate
type: SmallMoleculeReference

Compound/PW C000148/Stoichiometry/1.0
type: Stoichiometry
physical entity: Oxalacetic acid
stoichiometric coefficient: 1.0

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

L-Homoserine
type: SmallMoleculeReference
xref: Reference/BioCyc HOMO-SER
xref: Reference/ChEBI CHEBI 15699
xref: Reference/CAS 672-15-1
xref: Reference/KEGG Compound C00263
xref: Reference/PubChem-compound 12647
xref: Reference/HMDB HMDB0000719
xref: Reference/ChemSpider 12126
chemical formula: C4H9NO3
molecular weight: 119.05824
structure: ChemicalStructure/PW C000570

Aspartate kinase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

aspartate semialdehyde dehydrogenase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

a [protein]-(L-serine/L-threonine)
type: Protein
cellular location: Cytosol
entity reference: a [protein]-(L-serine/L-threonine)

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

aspartate kinase / homoserine dehydrogenase
type: Complex
component stoichiometry: Protein/29196/Stoichiometry/2.0
component: Unknown

Reference/CAS 56-84-8
type: UnificationXref
id: 56-84-8
db: CAS

L-Threonine
type: SmallMolecule
entity reference: L-Threonine
name: SubPathwayInput

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reference/PubChem-compound 970
type: UnificationXref
id: 970
db: PubChem-compound

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Interaction7993
type: MolecularInteraction
interaction type: direct_interaction
name: Aminomalonic acid inhibits 2-amino-3-ketobutyrate CoA ligase
participant: Aminomalonic acid
participant: 2-amino-3-ketobutyrate CoA ligase

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Compound/PW C000109 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Threonine
stoichiometric coefficient: 1.0