8 L-Glutamyl-tRNA(Glu) + 8 NADPH → 8 (S)-4-amino-5-oxopentanoate + 8 NADP + 8 tRNA(Glu)
8 Adenosine triphosphate + 8 Hydrogen Ion + 8 L-Glutamic acid + 8 tRNA(Glu) → 8 Adenosine monophosphate + 8 L-Glutamyl-tRNA(Glu) + 8 Pyrophosphate
8 (S)-4-amino-5-oxopentanoate → 8 5-Aminolevulinic acid
Coproporphyrinogen III + 2 Hydrogen Ion + Oxygen → 2 Carbon dioxide + Protoporphyrinogen IX + 2 Water
4 Hydrogen Ion + Uroporphyrinogen III → 4 Carbon dioxide + Coproporphyrinogen III
Hydroxymethylbilane → Uroporphyrinogen III + Water
4 Porphobilinogen + Water → 4 Ammonium + Hydroxymethylbilane
8 5-Aminolevulinic acid → 4 Hydrogen Ion + 4 Porphobilinogen + 8 Water
glutamate-1-semialdehyde aminotransferase
Hydroxymethylbilane → Uroporphyrinogen I + Water
Adenosine triphosphate + L-Glutamic acid + Water → Adenosine diphosphate + Hydrogen Ion + L-Glutamic acid + Phosphate
Hydrogen Ion (→), L-Glutamic acid (→) Transport: Bacteroides sp. 2_1_33B, Periplasmic Space to Bacteroides sp. 2_1_33B, Cytosol
L-Glutamic acid (→), Sodium (→) Transport: Bacteroides sp. 2_1_33B, Periplasmic Space to Bacteroides sp. 2_1_33B, Cytosol
NAD + Precorrin-2 → Hydrogen Ion + NADH + Sirohydrochlorin
Precorrin-1 + S-Adenosylmethionine → Precorrin-2 + S-Adenosylhomocysteine
S-Adenosylmethionine + Uroporphyrinogen III → Hydrogen Ion + Precorrin-1 + S-Adenosylhomocysteine
Hydrogen peroxide + ferroheme b → Heme D
Farnesyl pyrophosphate + Water + ferroheme b → Heme O + Pyrophosphate
Coproporphyrinogen III + S-Adenosylmethionine → 5'-Deoxyadenosine + Carbon dioxide + L-Methionine + Protoporphyrinogen IX
4 Hydrogen Ion + Uroporphyrinogen I → 4 Carbon dioxide + Coproporphyrinogen I
3 Oxygen + Protoporphyrinogen IX → 3 Hydrogen peroxide + Protoporphyrin IX
Fe2+ + Protoporphyrin IX → 2 Hydrogen Ion + ferroheme b
NAD + Precorrin 2 ↔ 2 Hydrogen Ion + NADH + Sirohydrochlorin
Protoporphyrinogen IX + menaquinone-8 → Menaquinol 6 + Protoporphyrin IX
Fe2+ + Sirohydrochlorin → 2 Hydrogen Ion + Siroheme