Escherichia coli str. K-12 substr. DH10B
type: BioSource
xref: Reference/TAXONOMY 316385

Serine Biosynthesis and Metabolism
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway570378
pathway component: SubPathwayInteraction570378
xref: Reference/PathWhiz PW000809
xref: Reference/SMPDB SMP0000829
name: SubPathway

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Acetyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc ACETYL-COA
xref: Reference/PubChem-compound 444493
xref: Reference/HMDB HMDB0001206
xref: Reference/ChemSpider 392413
xref: Reference/CAS 72-89-9
xref: Reference/ChEBI CHEBI 15351
xref: Reference/KEGG Compound C00024
chemical formula: C23H38N7O17P3S
molecular weight: 809.1258
structure: ChemicalStructure/PW C000940

Reference/PubChem-compound 439161
type: UnificationXref
id: 439161
db: PubChem-compound

Reference/ChEBI CHEBI 17460
type: UnificationXref
id: CHEBI:17460
db: ChEBI

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Glucose-specific phosphotransferase enzyme IIA component
type: ProteinReference
xref: Reference/UniProt P69783
organism: Escherichia coli str. K-12 substr. DH10B

Reference/PubChem-compound 439278
type: UnificationXref
id: 439278
db: PubChem-compound

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/ChemSpider 58238
type: UnificationXref
id: 58238
db: ChemSpider

Fructose 1,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001058
xref: Reference/BioCyc FRUCTOSE-16-DIPHOSPHATE
xref: Reference/CAS 488-69-7
xref: Reference/ChEBI CHEBI 16905
xref: Reference/ChemSpider 393165
xref: Reference/KEGG Compound C00354
xref: Reference/PubChem-compound 445557
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C000833

Reference/ChEBI CHEBI 16027
type: UnificationXref
id: CHEBI:16027
db: ChEBI

Reference/PubChem-compound 6251
type: UnificationXref
id: 6251
db: PubChem-compound

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Compound/PW C001176 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Mannitol 1-phosphate
stoichiometric coefficient: 1.0

Compound/PW C000611 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Mannitol
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0003498
type: UnificationXref
id: HMDB0003498
db: HMDB

Reference/KEGG Compound C00579
type: UnificationXref
id: C00579
db: KEGG Compound

2.7.1.69
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000395 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/28265 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906 Inner Membrane/Stoichiometry/1.0
right: Unknown
right: β-D-Glucose 6-phosphate
spontaneous: false
EC number: 2.7.1.69
left: β-D-Glucose
left: Unknown
name: HPr - phosphorylated + β-D-Glucose → HPr + β-D-Glucose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: PathwayEnzymeReaction/7363747
pathway order: PathwayEnzymeReaction/7363744
pathway order: PathwayEnzymeReaction/7363748
pathway order: PathwayEnzymeReaction/7363749
pathway order: PathwayEnzymeReaction/7363750
pathway order: PathwayEnzymeReaction/7363753
pathway order: PathwayEnzymeReaction/7363754
pathway order: PathwayEnzymeReaction/7363751
pathway order: PathwayEnzymeReaction/7363752
pathway order: PathwayEnzymeReaction/7363735
pathway order: PathwayEnzymeReaction/7363757
pathway order: PathwayEnzymeReaction/7363736
pathway order: PathwayEnzymeReaction/7363755
pathway order: PathwayEnzymeReaction/7363734
pathway order: PathwayEnzymeReaction/7363756
pathway order: PathwaySubPathway/570379
pathway order: PathwayEnzymeReaction/7363739
pathway order: PathwaySubPathway/570378
pathway order: PathwaySubPathway/570377
pathway order: PathwayEnzymeReaction/7363737
pathway order: PathwaySubPathway/570376
pathway order: PathwayEnzymeReaction/7363738
pathway order: PathwayEnzymeReaction/7363742
pathway order: PathwayEnzymeReaction/7363743
pathway order: PathwayEnzymeReaction/7363741
pathway component: Reaction1030445
pathway component: 5.3.1.9
pathway component: 2.7.1.69
pathway component: ReactionCatalysis1050214
pathway component: Serine Biosynthesis and Metabolism
pathway component: ReactionCatalysis1050215
pathway component: 3.1.3.11
pathway component: Fucose and Rhamnose Degradation
pathway component: TCA Cycle
pathway component: 2.7.1.40
pathway component: ReactionCatalysis1492211
pathway component: ReactionCatalysis1492213
pathway component: ReactionCatalysis1492215
pathway component: ReactionCatalysis1492214
pathway component: ReactionCatalysis790195
pathway component: 4.2.1.11
pathway component: 2.7.9.2
pathway component: 2.7.2.3
pathway component: Reaction1030381
pathway component: Lipopolysaccharide Biosynthesis
pathway component: 4.1.2.13
pathway component: Reaction1030385
pathway component: ReactionCatalysis1050146
pathway component: 1.2.1.12
pathway component: ReactionCatalysis1050147
pathway component: ReactionCatalysis733220
pathway component: ReactionCatalysis1050149
pathway component: ReactionCatalysis1050144
pathway component: ReactionCatalysis1050145
pathway component: ReactionCoupledTransportCatalysis36941
pathway component: 2.3.1.12
pathway component: Reaction1450334
pathway component: 1.1.1.17
pathway component: Reaction1450335
pathway component: ReactionCoupledTransportCatalysis11935
pathway component: ReactionCatalysis790180
pathway component: ReactionCatalysis1050193
pathway component: ReactionCatalysis1050150
pathway component: ReactionCatalysis1050194
pathway component: ReactionCatalysis1050195
pathway component: 5.3.1.1
pathway component: ReactionCatalysis1050196
xref: Reference/SMPDB SMP0512229
xref: Reference/PathWhiz PW538951
organism: Escherichia coli str. K-12 substr. DH10B

Fucose and Rhamnose Degradation
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway570377
pathway component: SubPathwayInteraction570377
xref: Reference/SMPDB SMP0000846
xref: Reference/PathWhiz PW000826
name: SubPathway

6-phosphofructokinase II
type: Protein
entity reference: 6-phosphofructokinase II

Reference/ChEBI CHEBI 15380
type: UnificationXref
id: CHEBI:15380
db: ChEBI

Fructose-1,6-bisphosphatase class 1
type: ProteinReference
xref: Reference/UniProt P0A993
organism: Escherichia coli str. K-12 substr. DH10B

Fructose-bisphosphate aldolase class 1
type: ProteinReference
xref: Reference/UniProt P0A991
organism: Escherichia coli str. K-12 substr. DH10B

6-phosphofructokinase-1
type: Complex
component stoichiometry: Protein/28265/Stoichiometry/4.0
component: Unknown
component: 6-phosphofructokinase II

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

NADH
type: SmallMolecule
cellular location: Cytosol
entity reference: NADH

Succinyl-CoA
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00091
xref: Reference/CAS 604-98-8
xref: Reference/ChemSpider 388307
xref: Reference/PubChem-compound 439161
xref: Reference/ChEBI CHEBI 15380
xref: Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
xref: Reference/HMDB HMDB0001022
chemical formula: C25H40N7O19P3S
molecular weight: 867.1312
structure: ChemicalStructure/PW C000808

Fructose 1,6-bisphosphate
type: SmallMolecule
entity reference: Fructose 1,6-bisphosphate

Compound/PW C001176/Stoichiometry/1.0
type: Stoichiometry
physical entity: Mannitol 1-phosphate
stoichiometric coefficient: 1.0

Carbon dioxide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Carbon dioxide

Lipopolysaccharide Biosynthesis
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway570376
pathway component: SubPathwayInteraction570376
xref: Reference/PathWhiz PW000831
xref: Reference/SMPDB SMP0000851
name: SubPathway

Reference/ChemSpider 5858
type: UnificationXref
id: 5858
db: ChemSpider

Adenosine monophosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine monophosphate

β-D-Glucose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 388538
xref: Reference/KEGG Compound C01172
xref: Reference/ChEBI CHEBI 17719
xref: Reference/HMDB HMDB0003498
xref: Reference/PubChem-compound 439427
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C001906

Reference/HMDB HMDB0003391
type: UnificationXref
id: HMDB0003391
db: HMDB

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

Compound/PW C001174/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Acetyldihydrolipoamide
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00221
type: UnificationXref
id: C00221
db: KEGG Compound

Acetyl-CoA
type: SmallMolecule
entity reference: Acetyl-CoA

Reference/ChemSpider 704
type: UnificationXref
id: 704
db: ChemSpider

ReactionCoupledTransportCatalysis36941
type: Catalysis
controller: mannitol PTS permease
controlled: 2.7.1.69
control type: ACTIVATION

Fructose-1,6-bisphosphatase class 2
type: ProteinReference
xref: Reference/UniProt P0A9C9
organism: Escherichia coli str. K-12 substr. DH10B

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/ChEBI CHEBI 17694
type: UnificationXref
id: CHEBI:17694
db: ChEBI

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

ReactionCoupledTransportCatalysis11935
type: Catalysis
controller: glucose PTS permease
controlled: 2.7.1.69
control type: ACTIVATION

Reference/CAS 488-69-7
type: UnificationXref
id: 488-69-7
db: CAS

Reference/CAS 15806-48-1
type: UnificationXref
id: 15806-48-1
db: CAS

Reference/CAS 138-08-9
type: UnificationXref
id: 138-08-9
db: CAS

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

ChemicalStructure/PW C000808
type: ChemicalStructure
structure format: SMILES

Pyruvate dehydrogenase E1
type: Complex
component stoichiometry: Protein/28265 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

Reference/ChemSpider 1046
type: UnificationXref
id: 1046
db: ChemSpider

Reference/SMPDB SMP0000846
type: UnificationXref
id: SMP0000846
db: SMPDB

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Glyceric acid 1,3-biphosphate
type: SmallMoleculeReference
xref: Reference/CAS 1981-49-3
xref: Reference/ChemSpider 663
xref: Reference/BioCyc DPG
xref: Reference/HMDB HMDB0001270
xref: Reference/KEGG Compound C00236
xref: Reference/PubChem-compound 683
chemical formula: C3H8O10P2
molecular weight: 265.95926
structure: ChemicalStructure/PW C000983

glucose PTS permease
type: Complex
component stoichiometry: Protein/28265 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown
component: Glucose-specific phosphotransferase enzyme IIA component

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Uncharacterized protein yggF
type: ProteinReference
xref: Reference/UniProt P21437
organism: Escherichia coli str. K-12 substr. DH10B

Reference/KEGG Compound C00236
type: UnificationXref
id: C00236
db: KEGG Compound

Compound/PW C001144 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00597
type: UnificationXref
id: C00597
db: KEGG Compound

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00354
type: UnificationXref
id: C00354
db: KEGG Compound

Reference/ChEBI CHEBI 16298
type: UnificationXref
id: CHEBI:16298
db: ChEBI

ReactionCatalysis1492211
type: Catalysis
controller: Unknown
controlled: 1.1.1.17
control type: ACTIVATION

ReactionCatalysis1492213
type: Catalysis
controller: Unknown
controlled: 2.3.1.12
control type: ACTIVATION

ReactionCatalysis1492215
type: Catalysis
controller: Pyruvate dehydrogenase E1
controlled: Reaction1450335
control type: ACTIVATION

ReactionCatalysis1492214
type: Catalysis
controller: Unknown
controlled: Reaction1450334
control type: ACTIVATION

Reference/TAXONOMY 316385
type: UnificationXref
id: 316385
db: TAXONOMY

Fructose 1,6-bisphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Fructose 1,6-bisphosphate

Fructose-1,6-bisphosphatase class 1
type: Protein
cellular location: Cytosol
entity reference: Fructose-1,6-bisphosphatase class 1

Phosphoenolpyruvic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Phosphoenolpyruvic acid

Fructose 6-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Fructose 6-phosphate

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

ChemicalStructure/PW C001906
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00248
type: UnificationXref
id: C00248
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

3-Phosphoglyceric acid
type: SmallMolecule
entity reference: 3-Phosphoglyceric acid

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Fructose 6-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Fructose 6-phosphate
name: SubPathwayInput

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

Reference/SMPDB SMP0000851
type: UnificationXref
id: SMP0000851
db: SMPDB

Reference/ChemSpider 388411
type: UnificationXref
id: 388411
db: ChemSpider

Reference/ChemSpider 388538
type: UnificationXref
id: 388538
db: ChemSpider

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/ChemSpider 388536
type: UnificationXref
id: 388536
db: ChemSpider

TCA Cycle
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway570379
pathway component: SubPathwayInteraction570379
xref: Reference/SMPDB SMP0000802
xref: Reference/PathWhiz PW000779
name: SubPathway

Adenosine triphosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Adenosine triphosphate

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Reference/BioCyc FRUCTOSE-6P
type: UnificationXref
id: FRUCTOSE-6P
db: BioCyc

Protein/28265 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Unknown
type: Protein
cellular location: Inner Membrane
entity reference: Unknown

Reference/BioCyc S-ACETYLDIHYDROLIPOAMIDE
type: UnificationXref
id: S-ACETYLDIHYDROLIPOAMIDE
db: BioCyc

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Pyruvic acid
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Pyruvic acid

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
entity reference: D-Glyceraldehyde 3-phosphate

Reference/ChemSpider 388307
type: UnificationXref
id: 388307
db: ChemSpider

Mannitol
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000765
xref: Reference/ChEBI CHEBI 16899
xref: Reference/KEGG Compound C00392
xref: Reference/PubChem-compound 6251
xref: Reference/CAS 69-65-8
xref: Reference/ChemSpider 6015
chemical formula: C6H14O6
molecular weight: 182.07904
structure: ChemicalStructure/PW C000611

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Glyceric acid 1,3-biphosphate
type: SmallMolecule
entity reference: Glyceric acid 1,3-biphosphate

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00020
type: UnificationXref
id: C00020
db: KEGG Compound

ChemicalStructure/PW C000913
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)CCCC[C@H](CCS)SC(=O)CCC(O)=O

Fructose-bisphosphate aldolase class 2
type: ProteinReference
xref: Reference/UniProt P0AB71
organism: Escherichia coli str. K-12 substr. DH10B

Compound/PW C000644/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Phosphoglyceric acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 62713
type: UnificationXref
id: 62713
db: ChemSpider

Reference/KEGG Compound C00024
type: UnificationXref
id: C00024
db: KEGG Compound

Protein/7216 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Uncharacterized protein yggF
stoichiometric coefficient: 2.0

Reference/KEGG Compound C00392
type: UnificationXref
id: C00392
db: KEGG Compound

Reference/CAS 940-69-2
type: UnificationXref
id: 940-69-2
db: CAS

Compound/PW C001906 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/UniProt P21829
type: UnificationXref
id: P21829
db: UniProt

Unknown
type: Protein
cellular location: Cytoplasm
entity reference: Unknown

Reference/SMPDB SMP0000802
type: UnificationXref
id: SMP0000802
db: SMPDB

Compound/PW C000164 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMolecule
entity reference: Water

Reference/BioCyc AMP
type: UnificationXref
id: AMP
db: BioCyc

Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/CAS 492-61-5
type: UnificationXref
id: 492-61-5
db: CAS

Compound/PW C000769 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lipoamide
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reference/KEGG Compound C01136
type: UnificationXref
id: C01136
db: KEGG Compound

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Compound/PW C000808/Stoichiometry/1.0
type: Stoichiometry
physical entity: Succinyl-CoA
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Reference/ChemSpider 643
type: UnificationXref
id: 643
db: ChemSpider

Reference/CAS 604-98-8
type: UnificationXref
id: 604-98-8
db: CAS

Reference/BioCyc PHOSPHO-ENOL-PYRUVATE
type: UnificationXref
id: PHOSPHO-ENOL-PYRUVATE
db: BioCyc

Mannitol 1-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Mannitol 1-phosphate

Reference/HMDB HMDB0000263
type: UnificationXref
id: HMDB0000263
db: HMDB

ChemicalStructure/PW C000180
type: ChemicalStructure
structure format: SMILES
structure data: OC(=O)C(=C)OP(O)(O)=O

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/PubChem-compound 64689
type: UnificationXref
id: 64689
db: PubChem-compound

Reference/BioCyc MANNITOL-1P
type: UnificationXref
id: MANNITOL-1P
db: BioCyc

Lipoamide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 863
xref: Reference/ChemSpider 840
xref: Reference/KEGG Compound C00248
xref: Reference/HMDB HMDB0000962
xref: Reference/BioCyc LIPOAMIDE
xref: Reference/CAS 940-69-2
xref: Reference/ChEBI CHEBI 17460
chemical formula: C8H15NOS2
molecular weight: 205.05951
structure: ChemicalStructure/PW C000769

mannitol PTS permease
type: Complex
component stoichiometry: Protein/28265 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Unknown

ReactionCatalysis1050214
type: Catalysis
controller: 6-phosphofructokinase-1
controlled: Reaction1030445
control type: ACTIVATION

Reference/PubChem-compound 663
type: UnificationXref
id: 663
db: PubChem-compound

Reference/BioCyc CPD0-341
type: UnificationXref
id: CPD0-341
db: BioCyc

ReactionCatalysis1050215
type: Catalysis
controller: phosphoglucose isomerase
controlled: 5.3.1.9
control type: ACTIVATION

3-Phosphoglyceric acid
type: SmallMoleculeReference
xref: Reference/BioCyc G3P
xref: Reference/PubChem-compound 724
xref: Reference/ChEBI CHEBI 17050
xref: Reference/ChemSpider 704
xref: Reference/CAS 820-11-1
xref: Reference/KEGG Compound C00597
xref: Reference/HMDB HMDB0000807
chemical formula: C3H7O7P
molecular weight: 185.99294
structure: ChemicalStructure/PW C000644

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Protein/28265 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 1.0

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/SMPDB SMP0000829
type: UnificationXref
id: SMP0000829
db: SMPDB

Reference/UniProt P0A991
type: UnificationXref
id: P0A991
db: UniProt

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Reference/CAS 61-19-8
type: UnificationXref
id: 61-19-8
db: CAS

ChemicalStructure/PW C000032
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C000395
type: ChemicalStructure
structure format: SMILES

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis790195
type: Catalysis
controller: triosephosphate isomerase
controlled: 5.3.1.1
control type: ACTIVATION

Unknown
type: ProteinReference

Reference/UniProt P06999
type: UnificationXref
id: P06999
db: UniProt

NAD
type: SmallMolecule
cellular location: Cytosol
entity reference: NAD

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/BioCyc DPG
type: UnificationXref
id: DPG
db: BioCyc

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

phosphoglucose isomerase
type: Complex
component stoichiometry: Protein/28265 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

Reference/PubChem-compound 445557
type: UnificationXref
id: 445557
db: PubChem-compound

Reference/UniProt P0A993
type: UnificationXref
id: P0A993
db: UniProt

2-Phospho-D-glyceric acid
type: SmallMolecule
entity reference: 2-Phospho-D-glyceric acid

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

Reference/HMDB HMDB0000045
type: UnificationXref
id: HMDB0000045
db: HMDB

Reference/ChemSpider 663
type: UnificationXref
id: 663
db: ChemSpider

ReactionCatalysis790180
type: Catalysis
controller: phosphoenolpyruvate synthetase
controlled: 2.7.9.2
control type: ACTIVATION

2-Phospho-D-glyceric acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 439278
xref: Reference/ChemSpider 388411
xref: Reference/ChEBI CHEBI 17835
xref: Reference/HMDB HMDB0003391
xref: Reference/BioCyc 2-PG
xref: Reference/KEGG Compound C00631
chemical formula: C3H7O7P
molecular weight: 185.99294
structure: ChemicalStructure/PW C001870

Reference/KEGG Compound C00074
type: UnificationXref
id: C00074
db: KEGG Compound

Reference/ChEBI CHEBI 17050
type: UnificationXref
id: CHEBI:17050
db: ChEBI

Dihydrolipoamide
type: SmallMolecule
entity reference: Dihydrolipoamide

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Dihydrolipoamide
type: SmallMoleculeReference
xref: Reference/ChemSpider 643
xref: Reference/CAS 3884-47-7
xref: Reference/KEGG Compound C00579
xref: Reference/PubChem-compound 663
xref: Reference/HMDB HMDB0000985
xref: Reference/BioCyc DIHYDROLIPOAMIDE
xref: Reference/ChEBI CHEBI 17694
chemical formula: C8H17NOS2
molecular weight: 207.07515
structure: ChemicalStructure/PW C000782

3-Phosphoglyceric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 3-Phosphoglyceric acid
name: SubPathwayInput

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

β-D-Glucose
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-Glucose

Reference/PubChem-compound 724
type: UnificationXref
id: 724
db: PubChem-compound

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

Protein/28265 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Reference/KEGG Compound C01169
type: UnificationXref
id: C01169
db: KEGG Compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Reference/KEGG Compound C00085
type: UnificationXref
id: C00085
db: KEGG Compound

Reference/KEGG Compound C01172
type: UnificationXref
id: C01172
db: KEGG Compound

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/HMDB HMDB0001022
type: UnificationXref
id: HMDB0001022
db: HMDB

Reference/ChEBI CHEBI 44897
type: UnificationXref
id: CHEBI:44897
db: ChEBI

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00091
type: UnificationXref
id: C00091
db: KEGG Compound

Reference/PathWhiz PW000809
type: UnificationXref
id: PW000809
db: PathWhiz

Reference/BioCyc G3P
type: UnificationXref
id: G3P
db: BioCyc

Reference/ChemSpider 840
type: UnificationXref
id: 840
db: ChemSpider

Protein/6107 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Fructose-1,6-bisphosphatase class 1
stoichiometric coefficient: 4.0

Reference/HMDB HMDB0001270
type: UnificationXref
id: HMDB0001270
db: HMDB

Compound/PW C000869/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 863
type: UnificationXref
id: 863
db: PubChem-compound

phosphoenolpyruvate synthetase
type: Complex
component stoichiometry: Protein/28265 Cytoplasm/Stoichiometry/2.0
cellular location: Cytoplasm
component: Unknown

Glyceraldehyde 3-phosphate dehydrogenase
type: Complex
component stoichiometry: Protein/28265 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Unknown

Reference/PubChem-compound 444493
type: UnificationXref
id: 444493
db: PubChem-compound

Reference/BioCyc LIPOAMIDE
type: UnificationXref
id: LIPOAMIDE
db: BioCyc

Reference/PubChem-compound 6083
type: UnificationXref
id: 6083
db: PubChem-compound

Compound/PW C000869 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Fructose-bisphosphate aldolase class 1
type: Protein
cellular location: Cytosol
entity reference: Fructose-bisphosphate aldolase class 1

Reference/BioCyc 2-PG
type: UnificationXref
id: 2-PG
db: BioCyc

Compound/PW C000913/Stoichiometry/1.0
type: Stoichiometry
physical entity: (S)-Succinyldihydrolipoamide
stoichiometric coefficient: 1.0

Glucose-specific phosphotransferase enzyme IIA component
type: Protein
cellular location: Inner Membrane
entity reference: Glucose-specific phosphotransferase enzyme IIA component

Reference/BioCyc ACETYL-COA
type: UnificationXref
id: ACETYL-COA
db: BioCyc

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C000079
type: ChemicalStructure
structure format: SMILES

Compound/PW C001174 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: S-Acetyldihydrolipoamide
stoichiometric coefficient: 1.0

Reference/ChemSpider 393165
type: UnificationXref
id: 393165
db: ChemSpider

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Compound/PW C000079 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C001104 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001058
type: UnificationXref
id: HMDB0001058
db: HMDB

ChemicalStructure/PW C001176
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C001174
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)SC(CCS)CCCCC(N)=O

Reference/ChemSpider 980
type: UnificationXref
id: 980
db: ChemSpider

Reference/ChEBI CHEBI 15903
type: UnificationXref
id: CHEBI:15903
db: ChEBI

Reference/CAS 820-11-1
type: UnificationXref
id: 820-11-1
db: CAS

Reference/HMDB HMDB0001177
type: UnificationXref
id: HMDB0001177
db: HMDB

2-Phospho-D-glyceric acid
type: SmallMolecule
cellular location: Cytosol
entity reference: 2-Phospho-D-glyceric acid

Compound/PW C001134 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

2.7.1.40
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000180/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Pyruvic acid
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.1.40
left: Adenosine diphosphate
left: Hydrogen Ion
left: Phosphoenolpyruvic acid
name: Adenosine diphosphate + Hydrogen Ion + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 6015
type: UnificationXref
id: 6015
db: ChemSpider

NADH
type: SmallMolecule
entity reference: NADH

S-Acetyldihydrolipoamide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: S-Acetyldihydrolipoamide

Compound/PW C000983 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glyceric acid 1,3-biphosphate
stoichiometric coefficient: 1.0

Compound/PW C000833 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 1,6-bisphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

β-D-Glucose 6-phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: β-D-Glucose 6-phosphate

Acetyl-CoA
type: SmallMolecule
cellular location: Cytosol
entity reference: Acetyl-CoA
name: SubPathwayInput

Adenosine monophosphate
type: SmallMoleculeReference
xref: Reference/CAS 61-19-8
xref: Reference/ChemSpider 5858
xref: Reference/HMDB HMDB0000045
xref: Reference/BioCyc AMP
xref: Reference/ChEBI CHEBI 16027
xref: Reference/PubChem-compound 6083
xref: Reference/KEGG Compound C00020
chemical formula: C10H14N5O7P
molecular weight: 347.06308
structure: ChemicalStructure/PW C000032

β-D-Glucose
type: SmallMoleculeReference
xref: Reference/PubChem-compound 64689
xref: Reference/ChemSpider 58238
xref: Reference/HMDB HMDB0000516
xref: Reference/KEGG Compound C00221
xref: Reference/CAS 492-61-5
xref: Reference/ChEBI CHEBI 15903
chemical formula: C6H12O6
molecular weight: 180.06339
structure: ChemicalStructure/PW C000395

Reference/ChEBI CHEBI 16807
type: UnificationXref
id: CHEBI:16807
db: ChEBI

ReactionCatalysis733220
type: Catalysis
controller: pyruvate kinase
controlled: 2.7.1.40
control type: ACTIVATION

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

Reference/PubChem-compound 1005
type: UnificationXref
id: 1005
db: PubChem-compound

SubPathwayInteraction570377
type: Interaction
name: SubPathwayReaction
name: SubPathway570377Reaction
participant: Dihydroxyacetone phosphate

SubPathwayInteraction570376
type: Interaction
name: SubPathway570376Reaction
name: SubPathwayReaction
participant: Fructose 6-phosphate

Reference/CAS 643-13-0
type: UnificationXref
id: 643-13-0
db: CAS

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 1981-49-3
type: UnificationXref
id: 1981-49-3
db: CAS

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Compound/PW C000180/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoenolpyruvic acid
stoichiometric coefficient: 1.0

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Water
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Water

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

SubPathwayInteraction570379
type: Interaction
name: SubPathway570379Reaction
name: SubPathwayReaction
participant: Acetyl-CoA

SubPathwayInteraction570378
type: Interaction
name: SubPathway570378Reaction
name: SubPathwayReaction
participant: 3-Phosphoglyceric acid

Compound/PW C000940/Stoichiometry/1.0
type: Stoichiometry
physical entity: Acetyl-CoA
stoichiometric coefficient: 1.0

triosephosphate isomerase
type: Complex
component stoichiometry: Protein/28265/Stoichiometry/2.0
component: Unknown

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Phosphatase ybhA
type: Protein
cellular location: Cytosol
entity reference: Phosphatase ybhA

Reference/HMDB HMDB0001526
type: UnificationXref
id: HMDB0001526
db: HMDB

Protein/28265/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/ChEBI CHEBI 16905
type: UnificationXref
id: CHEBI:16905
db: ChEBI

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Compound/PW C001870/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Phospho-D-glyceric acid
stoichiometric coefficient: 1.0

Lipoamide
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Lipoamide

Reference/PathWhiz PW000831
type: UnificationXref
id: PW000831
db: PathWhiz

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

fructose-1,6-bisphosphatase
type: Complex
component stoichiometry: Protein/7216 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Uncharacterized protein yggF

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Compound/PW C000644 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 3-Phosphoglyceric acid
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0001530
type: UnificationXref
id: HMDB0001530
db: HMDB

fructose bisphosphate aldolase
type: Complex
component stoichiometry: Protein/6157 Cytosol/Stoichiometry/10.0
component stoichiometry: Protein/6106 Cytosol/Stoichiometry/10.0
cellular location: Cytosol
component: Fructose-bisphosphate aldolase class 2
component: Fructose-bisphosphate aldolase class 1

Reference/ChEBI CHEBI 15946
type: UnificationXref
id: CHEBI:15946
db: ChEBI

ReactionCatalysis1050193
type: Catalysis
controller: fructose-1,6-bisphosphatase
controlled: 3.1.3.11
control type: ACTIVATION

Protein/28265 Cytosol/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

ReactionCatalysis1050194
type: Catalysis
controller: Fructose-1,6-bisphosphatase 1
controlled: 3.1.3.11
control type: ACTIVATION

ReactionCatalysis1050195
type: Catalysis
controller: fructose 1,6-bisphosphatase 2
controlled: 3.1.3.11
control type: ACTIVATION

ReactionCatalysis1050196
type: Catalysis
controller: Phosphatase ybhA
controlled: 3.1.3.11
control type: ACTIVATION

Reference/PathWhiz PW000826
type: UnificationXref
id: PW000826
db: PathWhiz

Reaction1030445
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000833/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000079/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: Fructose 1,6-bisphosphate
spontaneous: false
left: Fructose 6-phosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + Fructose 6-phosphate → Adenosine diphosphate + Fructose 1,6-bisphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

5.3.1.9
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000079 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001906 Cytoplasm/Stoichiometry/1.0
right: Fructose 6-phosphate
spontaneous: false
EC number: 5.3.1.9
left: β-D-Glucose 6-phosphate
name: β-D-Glucose 6-phosphate → Fructose 6-phosphate
conversion direction: LEFT_TO_RIGHT

Unknown
type: Protein
entity reference: Unknown

Compound/PW C001906 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose 6-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 683
type: UnificationXref
id: 683
db: PubChem-compound

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Protein/6157 Cytosol/Stoichiometry/10.0
type: Stoichiometry
physical entity: Fructose-bisphosphate aldolase class 2
stoichiometric coefficient: 10.0

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Fructose 6-phosphate
type: SmallMoleculeReference
xref: Reference/CAS 643-13-0
xref: Reference/HMDB HMDB0000124
xref: Reference/KEGG Compound C00085
xref: Reference/ChEBI CHEBI 15946
xref: Reference/BioCyc FRUCTOSE-6P
xref: Reference/PubChem-compound 69507
xref: Reference/ChemSpider 62713
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000079

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/PathWhiz PW000779
type: UnificationXref
id: PW000779
db: PathWhiz

Reference/ChEBI CHEBI 17835
type: UnificationXref
id: CHEBI:17835
db: ChEBI

Reference/BioCyc DIHYDROLIPOAMIDE
type: UnificationXref
id: DIHYDROLIPOAMIDE
db: BioCyc

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Compound/PW C000721 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/PubChem-compound 130418
type: UnificationXref
id: 130418
db: PubChem-compound

Reference/UniProt P69783
type: UnificationXref
id: P69783
db: UniProt

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Mannitol 1-phosphate
type: SmallMolecule
entity reference: Mannitol 1-phosphate

S-Acetyldihydrolipoamide
type: SmallMoleculeReference
xref: Reference/ChemSpider 1046
xref: Reference/HMDB HMDB0001526
xref: Reference/PubChem-compound 1076
xref: Reference/ChEBI CHEBI 16807
xref: Reference/KEGG Compound C01136
xref: Reference/BioCyc S-ACETYLDIHYDROLIPOAMIDE
chemical formula: C10H19NO2S2
molecular weight: 249.08572
structure: ChemicalStructure/PW C001174

Mannitol 1-phosphate
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001530
xref: Reference/BioCyc MANNITOL-1P
xref: Reference/KEGG Compound C00644
xref: Reference/CAS 15806-48-1
xref: Reference/ChemSpider 115387
xref: Reference/PubChem-compound 130418
xref: Reference/ChEBI CHEBI 16298
chemical formula: C6H15O9P
molecular weight: 262.04538
structure: ChemicalStructure/PW C001176

S-Acetyldihydrolipoamide
type: SmallMolecule
entity reference: S-Acetyldihydrolipoamide

Unknown
type: Protein
cellular location: Cytosol
entity reference: Unknown

Reference/ChemSpider 115387
type: UnificationXref
id: 115387
db: ChemSpider

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Reference/PubChem-compound 69507
type: UnificationXref
id: 69507
db: PubChem-compound

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C040034 Cytoplasm/Stoichiometry/2.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 2.0

3.1.3.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000079 Cytosol/Stoichiometry/1.0
right: Fructose 1,6-bisphosphate
right: Water
spontaneous: false
EC number: 3.1.3.11
left: Phosphate
left: Fructose 6-phosphate
name: Fructose 6-phosphate + Phosphate → Fructose 1,6-bisphosphate + Water
conversion direction: LEFT_TO_RIGHT

Mannitol
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Mannitol

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Fructose 6-phosphate
type: SmallMolecule
entity reference: Fructose 6-phosphate

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/HMDB HMDB0001206
type: UnificationXref
id: HMDB0001206
db: HMDB

Compound/PW C000180 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphoenolpyruvic acid
stoichiometric coefficient: 1.0

β-D-Glucose 6-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: β-D-Glucose 6-phosphate

ReactionCatalysis1050146
type: Catalysis
controller: phosphoglycerate mutase
controlled: Reaction1030381
control type: ACTIVATION

ReactionCatalysis1050147
type: Catalysis
controller: enolase
controlled: 4.2.1.11
control type: ACTIVATION

ReactionCatalysis1050149
type: Catalysis
controller: fructose bisphosphate aldolase
controlled: 4.1.2.13
control type: ACTIVATION

6-phosphofructokinase II
type: ProteinReference
xref: Reference/UniProt P06999

ReactionCatalysis1050144
type: Catalysis
controller: Glyceraldehyde 3-phosphate dehydrogenase
controlled: 1.2.1.12
control type: ACTIVATION

ReactionCatalysis1050145
type: Catalysis
controller: Unknown
controlled: 2.7.2.3
control type: ACTIVATION

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Phosphoenolpyruvic acid
type: SmallMoleculeReference
xref: Reference/CAS 138-08-9
xref: Reference/ChEBI CHEBI 44897
xref: Reference/KEGG Compound C00074
xref: Reference/BioCyc PHOSPHO-ENOL-PYRUVATE
xref: Reference/ChemSpider 980
xref: Reference/PubChem-compound 1005
xref: Reference/HMDB HMDB0000263
chemical formula: C3H5O6P
molecular weight: 167.98238
structure: ChemicalStructure/PW C000180

Reference/HMDB HMDB0000124
type: UnificationXref
id: HMDB0000124
db: HMDB

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Reference/GENE ONTOLOGY GO 0005737
type: UnificationXref
id: GO:0005737
db: GENE ONTOLOGY

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Glyceraldehyde 3-phosphate

ReactionCatalysis1050150
type: Catalysis
controller: Unknown
controlled: Reaction1030385
control type: ACTIVATION

Phosphoenolpyruvic acid
type: SmallMolecule
entity reference: Phosphoenolpyruvic acid

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16899
type: UnificationXref
id: CHEBI:16899
db: ChEBI

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/HMDB HMDB0000807
type: UnificationXref
id: HMDB0000807
db: HMDB

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Protein/6106 Cytosol/Stoichiometry/10.0
type: Stoichiometry
physical entity: Fructose-bisphosphate aldolase class 1
stoichiometric coefficient: 10.0

Compound/PW C001104 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Fructose-1,6-bisphosphatase class 2
type: Protein
cellular location: Cytosol
entity reference: Fructose-1,6-bisphosphatase class 2

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

ChemicalStructure/PW C000611
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

Reference/CAS 72-89-9
type: UnificationXref
id: 72-89-9
db: CAS

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

ChemicalStructure/PW C000983
type: ChemicalStructure
structure format: SMILES
structure data: O[C@H](COP(O)(O)=O)C(=O)OP(O)(O)=O

Compound/PW C000833/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 1,6-bisphosphate
stoichiometric coefficient: 1.0

Compound/PW C000395 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: β-D-Glucose
stoichiometric coefficient: 1.0

Cytoplasm
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005737

5.3.1.1
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
spontaneous: false
EC number: 5.3.1.1
left: D-Glyceraldehyde 3-phosphate
name: D-Glyceraldehyde 3-phosphate ↔ Dihydroxyacetone phosphate
conversion direction: REVERSIBLE

Reference/PubChem-compound 439425
type: UnificationXref
id: 439425
db: PubChem-compound

Reference/PubChem-compound 439427
type: UnificationXref
id: 439427
db: PubChem-compound

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

ChemicalStructure/PW C000940
type: ChemicalStructure
structure format: SMILES

Protein/6114 Cytosol/Stoichiometry/2.0
type: Stoichiometry
physical entity: Fructose-1,6-bisphosphatase class 2
stoichiometric coefficient: 2.0

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Compound/PW C001870 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-Phospho-D-glyceric acid
stoichiometric coefficient: 1.0

Hydrogen Ion
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Hydrogen Ion

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

2.7.9.2
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytoplasm/Stoichiometry/2.0
participant stoichiometry: Compound/PW C001420 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000180 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000032 Cytoplasm/Stoichiometry/1.0
right: Pyruvic acid
right: Water
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.9.2
left: Hydrogen Ion
left: Adenosine monophosphate
left: Phosphoenolpyruvic acid
left: Phosphate
name: Adenosine monophosphate + 2 Hydrogen Ion + Phosphate + Phosphoenolpyruvic acid → Adenosine triphosphate + Pyruvic acid + Water
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17719
type: UnificationXref
id: CHEBI:17719
db: ChEBI

Water
type: SmallMolecule
cellular location: Cytosol
entity reference: Water

Reference/BioCyc FRUCTOSE-16-DIPHOSPHATE
type: UnificationXref
id: FRUCTOSE-16-DIPHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

ChemicalStructure/PW C000833
type: ChemicalStructure
structure format: SMILES

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Compound/PW C000079/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

Reference/HMDB HMDB0000962
type: UnificationXref
id: HMDB0000962
db: HMDB

Compound/PW C001420 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Compound/PW C000079 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Fructose 6-phosphate
stoichiometric coefficient: 1.0

2.7.1.69
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000611 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/28265 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001176 Inner Membrane/Stoichiometry/1.0
right: Mannitol 1-phosphate
right: Unknown
spontaneous: false
EC number: 2.7.1.69
left: Mannitol
left: Unknown
name: HPr - phosphorylated + Mannitol → HPr + Mannitol 1-phosphate
conversion direction: LEFT_TO_RIGHT

fructose 1,6-bisphosphatase 2
type: Complex
component stoichiometry: Protein/6114 Cytosol/Stoichiometry/2.0
cellular location: Cytosol
component: Fructose-1,6-bisphosphatase class 2

Reference/SMPDB SMP0512229
type: UnificationXref
id: SMP0512229
db: SMPDB

Reference/PathWhiz PW538951
type: UnificationXref
id: PW538951
db: PathWhiz

Reference/ChemSpider 392413
type: UnificationXref
id: 392413
db: ChemSpider

ChemicalStructure/PW C000644
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C(O)=O

Reference/CAS 69-65-8
type: UnificationXref
id: 69-65-8
db: CAS

Phosphatase ybhA
type: ProteinReference
xref: Reference/UniProt P21829
organism: Escherichia coli str. K-12 substr. DH10B

Reference/UniProt P0A9C9
type: UnificationXref
id: P0A9C9
db: UniProt

Reference/KEGG Compound C00631
type: UnificationXref
id: C00631
db: KEGG Compound

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

ChemicalStructure/PW C000769
type: ChemicalStructure
structure format: SMILES
structure data: NC(=O)CCCCC1CCSS1

Compound/PW C000983/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glyceric acid 1,3-biphosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Compound/PW C000032 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine monophosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

(S)-Succinyldihydrolipoamide
type: SmallMoleculeReference
xref: Reference/BioCyc CPD0-341
xref: Reference/ChemSpider 388536
xref: Reference/PubChem-compound 439425
xref: Reference/ChEBI CHEBI 17432
xref: Reference/HMDB HMDB0001177
xref: Reference/KEGG Compound C01169
chemical formula: C12H21NO4S2
molecular weight: 307.0912
structure: ChemicalStructure/PW C000913

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/KEGG Compound C00644
type: UnificationXref
id: C00644
db: KEGG Compound

Succinyl-CoA
type: SmallMolecule
entity reference: Succinyl-CoA

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Glyceric acid 1,3-biphosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Glyceric acid 1,3-biphosphate

Reference/ChEBI CHEBI 17432
type: UnificationXref
id: CHEBI:17432
db: ChEBI

Phosphate
type: SmallMolecule
cellular location: Cytoplasm
entity reference: Phosphate

Compound/PW C000414 Cytoplasm/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C001870
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](OP(O)(O)=O)C(O)=O

Phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Phosphate

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000985
type: UnificationXref
id: HMDB0000985
db: HMDB

Fructose-1,6-bisphosphatase 1
type: Complex
component stoichiometry: Protein/6107 Cytosol/Stoichiometry/4.0
cellular location: Cytosol
component: Fructose-1,6-bisphosphatase class 1

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

pyruvate kinase
type: Complex
component stoichiometry: Protein/28265/Stoichiometry/4.0
component: Unknown

ChemicalStructure/PW C000782
type: ChemicalStructure
structure format: SMILES
structure data: OC(=N)CCCCC(S)CCS

Compound/PW C000782/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydrolipoamide
stoichiometric coefficient: 1.0

enolase
type: Complex
component stoichiometry: Protein/28265/Stoichiometry/2.0
component: Unknown

(S)-Succinyldihydrolipoamide
type: SmallMolecule
entity reference: (S)-Succinyldihydrolipoamide

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

Reference/PubChem-compound 1076
type: UnificationXref
id: 1076
db: PubChem-compound

Fructose-bisphosphate aldolase class 2
type: Protein
cellular location: Cytosol
entity reference: Fructose-bisphosphate aldolase class 2

Reference/UniProt P21437
type: UnificationXref
id: P21437
db: UniProt

Protein/28265/Stoichiometry/4.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 4.0

4.2.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001870/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000180/Stoichiometry/1.0
right: Water
right: Phosphoenolpyruvic acid
spontaneous: false
EC number: 4.2.1.11
left: 2-Phospho-D-glyceric acid
name: 2-Phospho-D-glyceric acid → Phosphoenolpyruvic acid + Water
conversion direction: LEFT_TO_RIGHT

2.7.2.3
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000983/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000644/Stoichiometry/1.0
right: 3-Phosphoglyceric acid
right: Adenosine triphosphate
spontaneous: false
EC number: 2.7.2.3
left: Adenosine diphosphate
left: Glyceric acid 1,3-biphosphate
name: Adenosine diphosphate + Glyceric acid 1,3-biphosphate → 3-Phosphoglyceric acid + Adenosine triphosphate
conversion direction: LEFT_TO_RIGHT

Reaction1030381
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001870/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000644/Stoichiometry/1.0
right: 2-Phospho-D-glyceric acid
spontaneous: false
left: 3-Phosphoglyceric acid
name: 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid
conversion direction: LEFT_TO_RIGHT

phosphoglycerate mutase
type: Complex
component stoichiometry: Protein/28265/Stoichiometry/2.0
component: Unknown

Reference/BioCyc 3-METHYLBENZYLSUCCINYL-COA
type: UnificationXref
id: 3-METHYLBENZYLSUCCINYL-COA
db: BioCyc

4.1.2.13
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000833 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869 Cytosol/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
right: D-Glyceraldehyde 3-phosphate
spontaneous: false
EC number: 4.1.2.13
left: Fructose 1,6-bisphosphate
name: Fructose 1,6-bisphosphate ↔ D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate
conversion direction: REVERSIBLE

Reaction1030385
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000644 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001870 Cytosol/Stoichiometry/1.0
right: 2-Phospho-D-glyceric acid
spontaneous: false
left: 3-Phosphoglyceric acid
name: 3-Phosphoglyceric acid → 2-Phospho-D-glyceric acid
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

1.2.1.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000983 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144 Cytosol/Stoichiometry/1.0
right: Hydrogen Ion
right: NADH
right: Glyceric acid 1,3-biphosphate
spontaneous: false
EC number: 1.2.1.12
left: Phosphate
left: NAD
left: D-Glyceraldehyde 3-phosphate
name: D-Glyceraldehyde 3-phosphate + NAD + Phosphate → Glyceric acid 1,3-biphosphate + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Reference/HMDB HMDB0000516
type: UnificationXref
id: HMDB0000516
db: HMDB

Uncharacterized protein yggF
type: Protein
cellular location: Cytosol
entity reference: Uncharacterized protein yggF

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

2.3.1.12
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001174/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000782/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000940/Stoichiometry/1.0
right: Coenzyme A
right: S-Acetyldihydrolipoamide
spontaneous: false
EC number: 2.3.1.12
left: Dihydrolipoamide
left: Acetyl-CoA
name: Acetyl-CoA + Dihydrolipoamide ↔ Coenzyme A + S-Acetyldihydrolipoamide
conversion direction: REVERSIBLE

Reference/ChEBI CHEBI 15351
type: UnificationXref
id: CHEBI:15351
db: ChEBI

Reaction1450334
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000808/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000782/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000913/Stoichiometry/1.0
right: Coenzyme A
right: (S)-Succinyldihydrolipoamide
spontaneous: false
left: Dihydrolipoamide
left: Succinyl-CoA
name: Dihydrolipoamide + Succinyl-CoA → (S)-Succinyldihydrolipoamide + Coenzyme A
conversion direction: LEFT_TO_RIGHT

1.1.1.17
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001176/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000079/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Mannitol 1-phosphate
right: NAD
spontaneous: false
EC number: 1.1.1.17
left: NADH
left: Fructose 6-phosphate
left: Hydrogen Ion
name: Fructose 6-phosphate + Hydrogen Ion + NADH ↔ Mannitol 1-phosphate + NAD
conversion direction: REVERSIBLE

Reference/CAS 3884-47-7
type: UnificationXref
id: 3884-47-7
db: CAS

Reaction1450335
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001174 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000769 Cytoplasm/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164 Cytoplasm/Stoichiometry/1.0
right: Carbon dioxide
right: S-Acetyldihydrolipoamide
spontaneous: false
left: Pyruvic acid
left: Lipoamide
name: Lipoamide + Pyruvic acid → Carbon dioxide + S-Acetyldihydrolipoamide
conversion direction: LEFT_TO_RIGHT

Reference/HMDB HMDB0000765
type: UnificationXref
id: HMDB0000765
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/UniProt P0AB71
type: UnificationXref
id: P0AB71
db: UniProt