Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C000504/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16813
type: UnificationXref
id: CHEBI:16813
db: ChEBI

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/ChEBI CHEBI 58695
type: UnificationXref
id: CHEBI:58695
db: ChEBI

Reference/ChEBI CHEBI 58694
type: UnificationXref
id: CHEBI:58694
db: ChEBI

TransportCatalysis37555
type: Catalysis
controller: D-galactonate transporter
controlled: Transport56558
control type: ACTIVATION

Reference/PubChem-compound 11850
type: UnificationXref
id: 11850
db: PubChem-compound

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C000504 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00446
type: UnificationXref
id: C00446
db: KEGG Compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/BioCyc GALACTOSE-1P
type: UnificationXref
id: GALACTOSE-1P
db: BioCyc

4.2.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000441/Stoichiometry/1.0
right: Water
right: 2-dehydro-3-deoxy-D-galactonate
spontaneous: false
EC number: 4.2.1.6
left: Galactonic acid
name: Galactonic acid → 2-dehydro-3-deoxy-D-galactonate + Water
conversion direction: LEFT_TO_RIGHT

2.7.1.58
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
spontaneous: false
EC number: 2.7.1.58
left: 2-dehydro-3-deoxy-D-galactonate
left: Adenosine triphosphate
name: 2-dehydro-3-deoxy-D-galactonate + Adenosine triphosphate → 2-dehydro-3-deoxy-D-galactonate 6-phosphate + Adenosine diphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

ReactionCoupledTransportCatalysis11272
type: Catalysis
controller: galactitol / sorbitol PTS permease
controlled: ReactionCoupledTransport11210
control type: ACTIVATION

Galactonic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Galactonic acid

ReactionCatalysis767803
type: Catalysis
controller: 6-phosphofructokinase II
controlled: 2.7.1.11
control type: ACTIVATION

ReactionCatalysis767804
type: Catalysis
controller: Unknown
controlled: 4.1.2.40
control type: ACTIVATION

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

ReactionCatalysis767805
type: Catalysis
controller: tagatose-1,6-bisphosphate aldolase 1
controlled: 4.1.2.40
control type: ACTIVATION

ReactionCatalysis767800
type: Catalysis
controller: 2-dehydro-3-deoxygalactonokinase
controlled: 2.7.1.58
control type: ACTIVATION

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

ReactionCatalysis767801
type: Catalysis
controller: KDPG and KHG aldolase
controlled: 4.1.2.21
control type: ACTIVATION

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ReactionCatalysis767802
type: Catalysis
controller: Alcohol dehydrogenase zinc-binding domain protein
controlled: 1.1.1.251
control type: ACTIVATION

Protein/27301/Stoichiometry/2.0
type: Stoichiometry
physical entity: Unknown
stoichiometric coefficient: 2.0

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

D-tagatose-1,6-bisphosphate aldolase subunit GatY
type: ProteinReference

Reference/ChemSpider 11357
type: UnificationXref
id: 11357
db: ChemSpider

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

Galactitol and Galactonate Degradation
type: Pathway
pathway order: PathwayTransport/5864762
pathway order: PathwayEnzymeReaction/5864759
pathway order: PathwayEnzymeReaction/5864749
pathway order: PathwayEnzymeReaction/5864757
pathway order: PathwayEnzymeReaction/5864758
pathway order: PathwaySubPathway/410806
pathway order: PathwayEnzymeReaction/5864756
pathway order: PathwaySubPathway/410805
pathway order: PathwayEnzymeReaction/5864752
pathway order: PathwaySubPathway/410804
pathway order: PathwayEnzymeReaction/5864760
pathway order: PathwayEnzymeReaction/5864761
pathway component: ReactionCoupledTransportCatalysis11272
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: Transport56558
pathway component: ReactionCatalysis767803
pathway component: ReactionCatalysis767804
pathway component: ReactionCatalysis767805
pathway component: ReactionCatalysis767799
pathway component: ReactionCatalysis767800
pathway component: ReactionCatalysis767801
pathway component: ReactionCatalysis767802
pathway component: ReactionCoupledTransport11210
pathway component: TransportCatalysis37555
pathway component: 4.2.1.6
pathway component: 2.7.1.58
pathway component: 4.1.2.21
pathway component: 1.1.1.251
pathway component: 2.7.1.11
pathway component: 4.1.2.40
xref: Reference/SMPDB SMP0644777
xref: Reference/PathWhiz PW685122
organism: Escherichia coli (strain B / BL21-DE3)

D-tagatose-1,6-bisphosphate aldolase subunit GatY
type: Protein
entity reference: D-tagatose-1,6-bisphosphate aldolase subunit GatY

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Reference/HMDB HMDB0000565
type: UnificationXref
id: HMDB0000565
db: HMDB

Reference/CAS 608-66-2
type: UnificationXref
id: 608-66-2
db: CAS

ChemicalStructure/PW C000441
type: ChemicalStructure
structure format: SMILES

Compound/PW C000441/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

Putative PTS IIA-like nitrogen-regulatory protein PtsN
type: Protein
cellular location: Inner Membrane
entity reference: Putative PTS IIA-like nitrogen-regulatory protein PtsN

Reference/PathWhiz PW685122
type: UnificationXref
id: PW685122
db: PathWhiz

Reference/ChemSpider 114198
type: UnificationXref
id: 114198
db: ChemSpider

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

Galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 110443
xref: Reference/KEGG Compound C00446
xref: Reference/ChEBI CHEBI 17973
xref: Reference/PubChem-compound 123912
xref: Reference/CAS 2255-14-3
xref: Reference/HMDB HMDB0000645
xref: Reference/BioCyc GALACTOSE-1P
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000504

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Reference/BioCyc D-GALACTONO-1,4-LACTONE
type: UnificationXref
id: D-GALACTONO-1,4-LACTONE
db: BioCyc

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Galactonic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Galactonic acid

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

D-Tagatofuranose 1,6-bisphosphate
type: SmallMolecule
entity reference: D-Tagatofuranose 1,6-bisphosphate

2-dehydro-3-deoxy-D-galactonate
type: SmallMolecule
entity reference: 2-dehydro-3-deoxy-D-galactonate

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

2-dehydro-3-deoxy-D-galactonate 6-phosphate
type: SmallMolecule
entity reference: 2-dehydro-3-deoxy-D-galactonate 6-phosphate

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C01697
type: UnificationXref
id: C01697
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

D-tagatofuranose 6-phosphate
type: SmallMolecule
entity reference: D-tagatofuranose 6-phosphate

Reference/HMDB HMDB0000107
type: UnificationXref
id: HMDB0000107
db: HMDB

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway410806
pathway order: SubPathwayInteractionSteps/SubPathway410805
pathway order: SubPathwayInteractionSteps/SubPathway410804
pathway component: SubPathwayInteraction410806
pathway component: SubPathwayInteraction410805
pathway component: SubPathwayInteraction410804
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Pyruvic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyruvic acid
name: SubPathwayInput

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

2-dehydro-3-deoxy-D-galactonate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57989
chemical formula: C6H9O6
molecular weight: 177.04047
structure: ChemicalStructure/PW C040943

2-dehydro-3-deoxy-D-galactonate 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58298
chemical formula: C6H8O9P
molecular weight: 254.99223
structure: ChemicalStructure/PW C040944

D-tagatofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58695
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040945

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

D-Tagatofuranose 1,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58694
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C040946

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

4.1.2.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: D-Glyceraldehyde 3-phosphate
right: Pyruvic acid
spontaneous: false
EC number: 4.1.2.21
left: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
name: 2-dehydro-3-deoxy-D-galactonate 6-phosphate → D-Glyceraldehyde 3-phosphate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

1.1.1.251
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000504/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040945/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: D-tagatofuranose 6-phosphate
spontaneous: false
EC number: 1.1.1.251
left: NAD
left: Galactose 1-phosphate
name: Galactose 1-phosphate + NAD → D-tagatofuranose 6-phosphate + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

2.7.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040945/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040946/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: D-Tagatofuranose 1,6-bisphosphate
spontaneous: false
EC number: 2.7.1.11
left: D-tagatofuranose 6-phosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + D-tagatofuranose 6-phosphate → Adenosine diphosphate + D-Tagatofuranose 1,6-bisphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

4.1.2.40
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040946/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
right: D-Glyceraldehyde 3-phosphate
spontaneous: false
EC number: 4.1.2.40
left: D-Tagatofuranose 1,6-bisphosphate
name: D-Tagatofuranose 1,6-bisphosphate → D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/SMPDB SMP0644777
type: UnificationXref
id: SMP0644777
db: SMPDB

galactitol / sorbitol PTS permease
type: Complex
component stoichiometry: Protein/55511 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: PTS system, galactitol-specific IIC subunit
component: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase
component: Putative PTS IIA-like nitrogen-regulatory protein PtsN

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
entity reference: D-Glyceraldehyde 3-phosphate

Protein-N(Pi)-phosphohistidine--sugar phosphotransferase
type: Protein
cellular location: Inner Membrane
entity reference: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Galactose 1-phosphate
type: SmallMolecule
entity reference: Galactose 1-phosphate

Compound/PW C040944/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Unknown
type: ProteinReference

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Galactitol
type: SmallMoleculeReference
xref: Reference/CAS 608-66-2
xref: Reference/HMDB HMDB0000107
xref: Reference/ChEBI CHEBI 16813
xref: Reference/ChemSpider 11357
xref: Reference/KEGG Compound C01697
xref: Reference/BioCyc 15-DIDEOXY-15-IMINO-D-GALACTITOL
xref: Reference/PubChem-compound 11850
chemical formula: C6H14O6
molecular weight: 182.07904
structure: ChemicalStructure/PW C000069

Compound/PW C000441 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Glyceraldehyde 3-phosphate
name: SubPathwayInput

Reference/ChEBI CHEBI 16534
type: UnificationXref
id: CHEBI:16534
db: ChEBI

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

D-galactonate transporter
type: ProteinReference

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 58298
type: UnificationXref
id: CHEBI:58298
db: ChEBI

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Galactitol
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Galactitol

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayInput

Water
type: SmallMolecule
entity reference: Water

Reference/PubChem-compound 123912
type: UnificationXref
id: 123912
db: PubChem-compound

Putative PTS IIA-like nitrogen-regulatory protein PtsN
type: ProteinReference
organism: Escherichia coli (strain B / BL21-DE3)

Protein-N(Pi)-phosphohistidine--sugar phosphotransferase
type: ProteinReference
organism: Escherichia coli (strain B / BL21-DE3)

PTS system, galactitol-specific IIC subunit
type: ProteinReference
organism: Escherichia coli (strain B / BL21-DE3)

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C040946/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Tagatofuranose 1,6-bisphosphate
stoichiometric coefficient: 1.0

Compound/PW C000441 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

Transport56558
type: Transport
participant stoichiometry: Compound/PW C000441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000441 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Galactonic acid
spontaneous: false
left: Galactonic acid
left: Hydrogen Ion
name: Galactonic acid (→), Hydrogen Ion (→) Transport: Escherichia coli (strain B / BL21-DE3), Periplasmic Space to Escherichia coli (strain B / BL21-DE3), Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reference/BioCyc 15-DIDEOXY-15-IMINO-D-GALACTITOL
type: UnificationXref
id: 15-DIDEOXY-15-IMINO-D-GALACTITOL
db: BioCyc

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Galactonic acid
type: SmallMolecule
entity reference: Galactonic acid

ChemicalStructure/PW C000069
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO

Galactonic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000565
xref: Reference/CAS 576-36-3
xref: Reference/ChEBI CHEBI 16534
xref: Reference/PubChem-compound 128869
xref: Reference/KEGG Compound C00880
xref: Reference/BioCyc D-GALACTONO-1,4-LACTONE
xref: Reference/ChemSpider 114198
chemical formula: C6H12O7
molecular weight: 196.0583
structure: ChemicalStructure/PW C000441

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Alcohol dehydrogenase zinc-binding domain protein
type: Protein
entity reference: Alcohol dehydrogenase zinc-binding domain protein

KDPG and KHG aldolase
type: Protein
entity reference: KDPG and KHG aldolase

2-dehydro-3-deoxygalactonokinase
type: Protein
entity reference: 2-dehydro-3-deoxygalactonokinase

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

Reference/ChemSpider 110443
type: UnificationXref
id: 110443
db: ChemSpider

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

D-tagatose-1,6-bisphosphate aldolase subunit GatZ
type: Protein
entity reference: D-tagatose-1,6-bisphosphate aldolase subunit GatZ

Compound/PW C040943/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-dehydro-3-deoxy-D-galactonate
stoichiometric coefficient: 1.0

Protein/55511 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: PTS system, galactitol-specific IIC subunit
stoichiometric coefficient: 2.0

Reference/ChEBI CHEBI 17973
type: UnificationXref
id: CHEBI:17973
db: ChEBI

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C040945/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-tagatofuranose 6-phosphate
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

KDPG and KHG aldolase
type: ProteinReference

2-dehydro-3-deoxygalactonokinase
type: ProteinReference

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

D-tagatose-1,6-bisphosphate aldolase subunit GatZ
type: ProteinReference

Alcohol dehydrogenase zinc-binding domain protein
type: ProteinReference

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

ChemicalStructure/PW C040943
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)C(O)CC(=O)C([O-])=O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

ChemicalStructure/PW C040946
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C040945
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

ChemicalStructure/PW C040944
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP([O-])([O-])=O)C(O)CC(=O)C([O-])=O

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

ReactionCoupledTransport11210
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000504 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000069 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/40905 Inner Membrane/Stoichiometry/1.0
right: Phosphocarrier protein HPr
right: Galactose 1-phosphate
spontaneous: false
left: Phosphocarrier protein HPr
left: Galactitol
name: Galactitol + HPr - phosphorylated → Galactose 1-phosphate + HPr
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

PTS system, galactitol-specific IIC subunit
type: Protein
cellular location: Inner Membrane
entity reference: PTS system, galactitol-specific IIC subunit

Phosphocarrier protein HPr
type: Protein
cellular location: Inner Membrane
entity reference: Phosphocarrier protein HPr

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

Reference/TAXONOMY 469008
type: UnificationXref
id: 469008
db: TAXONOMY

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

D-galactonate transporter
type: Protein
entity reference: D-galactonate transporter

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00880
type: UnificationXref
id: C00880
db: KEGG Compound

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Escherichia coli (strain B / BL21-DE3)
type: BioSource
xref: Reference/TAXONOMY 469008

6-phosphofructokinase II
type: Complex
component stoichiometry: Protein/27301/Stoichiometry/2.0
component: Unknown

Reference/CAS 2255-14-3
type: UnificationXref
id: 2255-14-3
db: CAS

tagatose-1,6-bisphosphate aldolase 1
type: Complex
component: D-tagatose-1,6-bisphosphate aldolase subunit GatZ
component: D-tagatose-1,6-bisphosphate aldolase subunit GatY

Compound/PW C000869/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 128869
type: UnificationXref
id: 128869
db: PubChem-compound

Galactose 1-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Galactose 1-phosphate

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

ChemicalStructure/PW C000504
type: ChemicalStructure
structure format: SMILES

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Unknown
type: Protein
entity reference: Unknown

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

SubPathwayInteraction410806
type: Interaction
name: SubPathway410806Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

SubPathwayInteraction410805
type: Interaction
name: SubPathwayReaction
name: SubPathway410805Reaction
participant: D-Glyceraldehyde 3-phosphate

Reference/CAS 576-36-3
type: UnificationXref
id: 576-36-3
db: CAS

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

SubPathwayInteraction410804
type: Interaction
name: SubPathway410804Reaction
name: SubPathwayReaction
participant: Pyruvic acid

ReactionCatalysis767799
type: Catalysis
controller: Unknown
controlled: 4.2.1.6
control type: ACTIVATION

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Phosphocarrier protein HPr
type: ProteinReference
organism: Escherichia coli (strain B / BL21-DE3)

Reference/ChEBI CHEBI 57989
type: UnificationXref
id: CHEBI:57989
db: ChEBI

Compound/PW C000069 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactitol
stoichiometric coefficient: 1.0

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000645
type: UnificationXref
id: HMDB0000645
db: HMDB

Protein/40905 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphocarrier protein HPr
stoichiometric coefficient: 1.0