Reference/UniProt G9Y359
type: UnificationXref
id: G9Y359
db: UniProt

ReactionCoupledTransportCatalysis13473
type: Catalysis
controller: galactitol / sorbitol PTS permease
controlled: ReactionCoupledTransport13411
control type: ACTIVATION

Reference/PubChem-compound 6022
type: UnificationXref
id: 6022
db: PubChem-compound

Compound/PW C000504/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Reference/UniProt G9Y353
type: UnificationXref
id: G9Y353
db: UniProt

Reference/ChEBI CHEBI 16813
type: UnificationXref
id: CHEBI:16813
db: ChEBI

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/ChEBI CHEBI 58695
type: UnificationXref
id: CHEBI:58695
db: ChEBI

Reference/ChEBI CHEBI 58694
type: UnificationXref
id: CHEBI:58694
db: ChEBI

Reference/PubChem-compound 11850
type: UnificationXref
id: 11850
db: PubChem-compound

NADH
type: SmallMolecule
entity reference: NADH

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C000504 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactose 1-phosphate
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00446
type: UnificationXref
id: C00446
db: KEGG Compound

Reference/HMDB HMDB0000538
type: UnificationXref
id: HMDB0000538
db: HMDB

NAD
type: SmallMolecule
entity reference: NAD

Reference/BioCyc ATP
type: UnificationXref
id: ATP
db: BioCyc

Reference/BioCyc GALACTOSE-1P
type: UnificationXref
id: GALACTOSE-1P
db: BioCyc

galactitol / sorbitol PTS permease
type: Complex
component stoichiometry: Protein/61529 Inner Membrane/Stoichiometry/2.0
cellular location: Inner Membrane
component: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
component: Putative galactitol-specific phosphotransferase enzyme IIB component
component: PTS system Galactitol-specific IIC component

Compound/PW C000414/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine triphosphate
stoichiometric coefficient: 1.0

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Pyruvic acid
type: SmallMolecule
entity reference: Pyruvic acid

SubPathwayInteraction420388
type: Interaction
name: SubPathway420388Reaction
name: SubPathwayReaction
participant: D-Glyceraldehyde 3-phosphate

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

SubPathwayInteraction420387
type: Interaction
name: SubPathway420387Reaction
name: SubPathwayReaction
participant: Pyruvic acid

Reference/BioCyc ADP
type: UnificationXref
id: ADP
db: BioCyc

Pyruvic acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 1060
xref: Reference/HMDB HMDB0000243
xref: Reference/CAS 127-17-3
xref: Reference/BioCyc PYRUVATE
xref: Reference/KEGG Compound C00022
xref: Reference/ChEBI CHEBI 32816
xref: Reference/ChemSpider 1031
chemical formula: C3H4O3
molecular weight: 88.016045
structure: ChemicalStructure/PW C000164

Reference/SMPDB SMP0644836
type: UnificationXref
id: SMP0644836
db: SMPDB

SubPathwayInteraction420389
type: Interaction
name: SubPathwayReaction
name: SubPathway420389Reaction
participant: Dihydroxyacetone phosphate

Galactonic acid
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Galactonic acid

Compound/PW C001034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Adenosine diphosphate
stoichiometric coefficient: 1.0

Reference/ChemSpider 5742
type: UnificationXref
id: 5742
db: ChemSpider

Reference/UniProt G9YCG1
type: UnificationXref
id: G9YCG1
db: UniProt

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005829
type: UnificationXref
id: GO:0005829
db: GENE ONTOLOGY

Transport62279
type: Transport
participant stoichiometry: Compound/PW C000441 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Cytosol/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000441 Periplasmic Space/Stoichiometry/1.0
right: Hydrogen Ion
right: Galactonic acid
spontaneous: false
left: Galactonic acid
left: Hydrogen Ion
name: Galactonic acid (→), Hydrogen Ion (→) Transport: Hafnia alvei ATCC 51873, Periplasmic Space to Hafnia alvei ATCC 51873, Cytosol
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 11357
type: UnificationXref
id: 11357
db: ChemSpider

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Reference/ChemSpider 709
type: UnificationXref
id: 709
db: ChemSpider

TransportCatalysis42919
type: Catalysis
controller: Transporter, major facilitator family protein
controlled: Transport62279
control type: ACTIVATION

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/GENE ONTOLOGY GO 0070258
type: UnificationXref
id: GO:0070258
db: GENE ONTOLOGY

Reference/HMDB HMDB0000565
type: UnificationXref
id: HMDB0000565
db: HMDB

Reference/CAS 608-66-2
type: UnificationXref
id: 608-66-2
db: CAS

ChemicalStructure/PW C000441
type: ChemicalStructure
structure format: SMILES

Compound/PW C000441/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 114198
type: UnificationXref
id: 114198
db: ChemSpider

D-Glyceraldehyde 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GAP
xref: Reference/ChEBI CHEBI 17138
xref: Reference/HMDB HMDB0001112
xref: Reference/ChemSpider 709
xref: Reference/KEGG Compound C00661
xref: Reference/PubChem-compound 729
xref: Reference/CAS 591-59-3
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C000869

Galactose 1-phosphate
type: SmallMoleculeReference
xref: Reference/ChemSpider 110443
xref: Reference/KEGG Compound C00446
xref: Reference/ChEBI CHEBI 17973
xref: Reference/PubChem-compound 123912
xref: Reference/CAS 2255-14-3
xref: Reference/HMDB HMDB0000645
xref: Reference/BioCyc GALACTOSE-1P
chemical formula: C6H13O9P
molecular weight: 260.02972
structure: ChemicalStructure/PW C000504

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Reference/BioCyc D-GALACTONO-1,4-LACTONE
type: UnificationXref
id: D-GALACTONO-1,4-LACTONE
db: BioCyc

Cytosol
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005829

Adenosine triphosphate
type: SmallMolecule
entity reference: Adenosine triphosphate

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Phosphocarrier protein HPr
type: Protein
cellular location: Inner Membrane
entity reference: Phosphocarrier protein HPr

Galactonic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Galactonic acid

tagatose-bisphosphate aldolase
type: Protein
entity reference: tagatose-bisphosphate aldolase

Phosphocarrier protein HPr
type: ProteinReference
xref: Reference/UniProt G9YCG1
organism: Hafnia alvei ATCC 51873

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
type: Protein
cellular location: Inner Membrane
entity reference: Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2

Reference/KEGG Compound C00008
type: UnificationXref
id: C00008
db: KEGG Compound

Reference/TAXONOMY 1002364
type: UnificationXref
id: 1002364
db: TAXONOMY

Hydrogen Ion
type: SmallMolecule
cellular location: Cytosol
entity reference: Hydrogen Ion

Protein/31344 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphocarrier protein HPr
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

D-Tagatofuranose 1,6-bisphosphate
type: SmallMolecule
entity reference: D-Tagatofuranose 1,6-bisphosphate

Reference/UniProt G9YAL6
type: UnificationXref
id: G9YAL6
db: UniProt

2-dehydro-3-deoxy-D-galactonate
type: SmallMolecule
entity reference: 2-dehydro-3-deoxy-D-galactonate

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

2-dehydro-3-deoxy-D-galactonate 6-phosphate
type: SmallMolecule
entity reference: 2-dehydro-3-deoxy-D-galactonate 6-phosphate

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Inner Membrane
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0070258

Reference/KEGG Compound C01697
type: UnificationXref
id: C01697
db: KEGG Compound

Reference/KEGG Compound C00002
type: UnificationXref
id: C00002
db: KEGG Compound

Reference/ChemSpider 1031
type: UnificationXref
id: 1031
db: ChemSpider

D-tagatofuranose 6-phosphate
type: SmallMolecule
entity reference: D-tagatofuranose 6-phosphate

Reference/HMDB HMDB0000107
type: UnificationXref
id: HMDB0000107
db: HMDB

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

tagatose-1,6-bisphosphate aldolase 1
type: Complex
component: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit
component: tagatose-bisphosphate aldolase

tagatose-1,6-bisphosphate aldolase 2
type: Complex
component: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit
component: tagatose-bisphosphate aldolase

6-phosphofructokinase II
type: Complex
component stoichiometry: Protein/61526/Stoichiometry/2.0
component: Phosphofructokinase

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway420389
pathway order: SubPathwayInteractionSteps/SubPathway420387
pathway order: SubPathwayInteractionSteps/SubPathway420388
pathway component: SubPathwayInteraction420388
pathway component: SubPathwayInteraction420387
pathway component: SubPathwayInteraction420389
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Compound/PW C040034 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Pyruvic acid
type: SmallMolecule
cellular location: Cytosol
entity reference: Pyruvic acid
name: SubPathwayInput

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Putative galactitol-specific phosphotransferase enzyme IIB component
type: ProteinReference
xref: Reference/UniProt G9Y6Y5
organism: Hafnia alvei ATCC 51873

Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
type: ProteinReference
xref: Reference/UniProt G9Y6Y4
organism: Hafnia alvei ATCC 51873

2-dehydro-3-deoxy-D-galactonate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 57989
chemical formula: C6H9O6
molecular weight: 177.04047
structure: ChemicalStructure/PW C040943

2-dehydro-3-deoxy-D-galactonate 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58298
chemical formula: C6H8O9P
molecular weight: 254.99223
structure: ChemicalStructure/PW C040944

D-tagatofuranose 6-phosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58695
chemical formula: C6H11O9P
molecular weight: 258.01517
structure: ChemicalStructure/PW C040945

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

D-Tagatofuranose 1,6-bisphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 58694
chemical formula: C6H14O12P2
molecular weight: 339.99606
structure: ChemicalStructure/PW C040946

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

Reference/PubChem-compound 5957
type: UnificationXref
id: 5957
db: PubChem-compound

Reference/GENE ONTOLOGY GO 0005620
type: UnificationXref
id: GO:0005620
db: GENE ONTOLOGY

Reference/ChEBI CHEBI 17138
type: UnificationXref
id: CHEBI:17138
db: ChEBI

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
entity reference: D-Glyceraldehyde 3-phosphate

Reference/UniProt G9Y6Y6
type: UnificationXref
id: G9Y6Y6
db: UniProt

Reference/UniProt G9Y6Y4
type: UnificationXref
id: G9Y6Y4
db: UniProt

Reference/UniProt G9Y6Y5
type: UnificationXref
id: G9Y6Y5
db: UniProt

Reference/KEGG Compound C00022
type: UnificationXref
id: C00022
db: KEGG Compound

Reference/CAS 56-65-5
type: UnificationXref
id: 56-65-5
db: CAS

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Galactose 1-phosphate
type: SmallMolecule
entity reference: Galactose 1-phosphate

Compound/PW C040944/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
stoichiometric coefficient: 1.0

Adenosine diphosphate
type: SmallMolecule
entity reference: Adenosine diphosphate

Reference/HMDB HMDB0000243
type: UnificationXref
id: HMDB0000243
db: HMDB

Adenosine diphosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00008
xref: Reference/PubChem-compound 6022
xref: Reference/ChemSpider 5800
xref: Reference/CAS 58-64-0
xref: Reference/BioCyc ADP
xref: Reference/ChEBI CHEBI 16761
xref: Reference/HMDB HMDB0001341
chemical formula: C10H15N5O10P2
molecular weight: 427.02942
structure: ChemicalStructure/PW C001034

Galactitol
type: SmallMoleculeReference
xref: Reference/CAS 608-66-2
xref: Reference/HMDB HMDB0000107
xref: Reference/ChEBI CHEBI 16813
xref: Reference/ChemSpider 11357
xref: Reference/KEGG Compound C01697
xref: Reference/BioCyc 15-DIDEOXY-15-IMINO-D-GALACTITOL
xref: Reference/PubChem-compound 11850
chemical formula: C6H14O6
molecular weight: 182.07904
structure: ChemicalStructure/PW C000069

Compound/PW C000441 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

D-Glyceraldehyde 3-phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: D-Glyceraldehyde 3-phosphate
name: SubPathwayInput

ReactionCatalysis822207
type: Catalysis
controller: Putative L-iditol 2-dehydrogenase
controlled: 1.1.1.251
control type: ACTIVATION

Reference/ChEBI CHEBI 16534
type: UnificationXref
id: CHEBI:16534
db: ChEBI

ReactionCatalysis822205
type: Catalysis
controller: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase
controlled: 4.1.2.21
control type: ACTIVATION

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ReactionCatalysis822204
type: Catalysis
controller: 2-dehydro-3-deoxygalactonokinase
controlled: 2.7.1.58
control type: ACTIVATION

ReactionCatalysis822201
type: Catalysis
controller: Starvation-sensing protein RspA
controlled: 4.2.1.6
control type: ACTIVATION

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 58298
type: UnificationXref
id: CHEBI:58298
db: ChEBI

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

Galactitol
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Galactitol

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Dihydroxyacetone phosphate
type: SmallMolecule
cellular location: Cytosol
entity reference: Dihydroxyacetone phosphate
name: SubPathwayInput

Water
type: SmallMolecule
entity reference: Water

Reference/PubChem-compound 123912
type: UnificationXref
id: 123912
db: PubChem-compound

Reference/HMDB HMDB0001341
type: UnificationXref
id: HMDB0001341
db: HMDB

Compound/PW C040946/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Tagatofuranose 1,6-bisphosphate
stoichiometric coefficient: 1.0

Starvation-sensing protein RspA
type: ProteinReference
xref: Reference/UniProt G9Y5M5

2-dehydro-3-deoxygalactonokinase
type: ProteinReference
xref: Reference/UniProt G9Y9G6

Compound/PW C000441 Cytosol/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactonic acid
stoichiometric coefficient: 1.0

2-dehydro-3-deoxy-6-phosphogalactonate aldolase
type: ProteinReference
xref: Reference/UniProt G9Y9G7

Galactitol and Galactonate Degradation
type: Pathway
pathway order: PathwayEnzymeReaction/5939909
pathway order: PathwayEnzymeReaction/5939907
pathway order: PathwayEnzymeReaction/5939918
pathway order: PathwaySubPathway/420389
pathway order: PathwaySubPathway/420388
pathway order: PathwaySubPathway/420387
pathway order: PathwayEnzymeReaction/5939902
pathway order: PathwayTransport/5939919
pathway order: PathwayEnzymeReaction/5939912
pathway order: PathwayEnzymeReaction/5939917
pathway order: PathwayEnzymeReaction/5939905
pathway order: PathwayEnzymeReaction/5939916
pathway component: ReactionCatalysis822207
pathway component: ReactionCoupledTransportCatalysis13473
pathway component: 1.1.1.251
pathway component: ReactionCatalysis822205
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: 4.1.2.21
pathway component: 2.7.1.58
pathway component: ReactionCatalysis822204
pathway component: ReactionCatalysis822201
pathway component: ReactionCatalysis822212
pathway component: ReactionCoupledTransport13411
pathway component: TransportCatalysis42919
pathway component: 4.2.1.6
pathway component: 4.1.2.40
pathway component: 2.7.1.11
pathway component: Transport62279
pathway component: ReactionCatalysis822210
pathway component: ReactionCatalysis822211
xref: Reference/PathWhiz PW685181
xref: Reference/SMPDB SMP0644836
organism: Hafnia alvei ATCC 51873

PTS system Galactitol-specific IIC component
type: ProteinReference
xref: Reference/UniProt G9Y6Y6
organism: Hafnia alvei ATCC 51873

Reference/UniProt G9YDN9
type: UnificationXref
id: G9YDN9
db: UniProt

Putative L-iditol 2-dehydrogenase
type: ProteinReference
xref: Reference/UniProt G9Y8I3

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Phosphofructokinase
type: ProteinReference
xref: Reference/UniProt G9YAL6

D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit
type: ProteinReference
xref: Reference/UniProt G9Y359

Reference/BioCyc 15-DIDEOXY-15-IMINO-D-GALACTITOL
type: UnificationXref
id: 15-DIDEOXY-15-IMINO-D-GALACTITOL
db: BioCyc

Transporter, major facilitator family protein
type: ProteinReference
xref: Reference/UniProt G9YDN9

ChemicalStructure/PW C001034
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0001112
type: UnificationXref
id: HMDB0001112
db: HMDB

Galactonic acid
type: SmallMolecule
entity reference: Galactonic acid

ChemicalStructure/PW C000069
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)CO

Galactonic acid
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000565
xref: Reference/CAS 576-36-3
xref: Reference/ChEBI CHEBI 16534
xref: Reference/PubChem-compound 128869
xref: Reference/KEGG Compound C00880
xref: Reference/BioCyc D-GALACTONO-1,4-LACTONE
xref: Reference/ChemSpider 114198
chemical formula: C6H12O7
molecular weight: 196.0583
structure: ChemicalStructure/PW C000441

Reference/PathWhiz PW685181
type: UnificationXref
id: PW685181
db: PathWhiz

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChEBI CHEBI 15422
type: UnificationXref
id: CHEBI:15422
db: ChEBI

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

ReactionCoupledTransport13411
type: TransportWithBiochemicalReaction
participant stoichiometry: Compound/PW C000504 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000069 Inner Membrane/Stoichiometry/1.0
participant stoichiometry: Protein/31344 Inner Membrane/Stoichiometry/1.0
right: Phosphocarrier protein HPr
right: Galactose 1-phosphate
spontaneous: false
left: Phosphocarrier protein HPr
left: Galactitol
name: Galactitol + HPr - phosphorylated → Galactose 1-phosphate + HPr
conversion direction: LEFT_TO_RIGHT

4.2.1.6
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000441/Stoichiometry/1.0
right: Water
right: 2-dehydro-3-deoxy-D-galactonate
spontaneous: false
EC number: 4.2.1.6
left: Galactonic acid
name: Galactonic acid → 2-dehydro-3-deoxy-D-galactonate + Water
conversion direction: LEFT_TO_RIGHT

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C000164/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyruvic acid
stoichiometric coefficient: 1.0

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 591-59-3
type: UnificationXref
id: 591-59-3
db: CAS

Reference/ChemSpider 110443
type: UnificationXref
id: 110443
db: ChemSpider

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Reference/CAS 127-17-3
type: UnificationXref
id: 127-17-3
db: CAS

Reference/UniProt G9Y8I3
type: UnificationXref
id: G9Y8I3
db: UniProt

Compound/PW C040943/Stoichiometry/1.0
type: Stoichiometry
physical entity: 2-dehydro-3-deoxy-D-galactonate
stoichiometric coefficient: 1.0

1.1.1.251
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000504/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040945/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADH
right: Hydrogen Ion
right: D-tagatofuranose 6-phosphate
spontaneous: false
EC number: 1.1.1.251
left: NAD
left: Galactose 1-phosphate
name: Galactose 1-phosphate + NAD → D-tagatofuranose 6-phosphate + Hydrogen Ion + NADH
conversion direction: LEFT_TO_RIGHT

4.1.2.21
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000164/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: D-Glyceraldehyde 3-phosphate
right: Pyruvic acid
spontaneous: false
EC number: 4.1.2.21
left: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
name: 2-dehydro-3-deoxy-D-galactonate 6-phosphate → D-Glyceraldehyde 3-phosphate + Pyruvic acid
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17973
type: UnificationXref
id: CHEBI:17973
db: ChEBI

2.7.1.58
type: BiochemicalReaction
participant stoichiometry: Compound/PW C040944/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040943/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: 2-dehydro-3-deoxy-D-galactonate 6-phosphate
spontaneous: false
EC number: 2.7.1.58
left: 2-dehydro-3-deoxy-D-galactonate
left: Adenosine triphosphate
name: 2-dehydro-3-deoxy-D-galactonate + Adenosine triphosphate → 2-dehydro-3-deoxy-D-galactonate 6-phosphate + Adenosine diphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Adenosine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15422
xref: Reference/PubChem-compound 5957
xref: Reference/HMDB HMDB0000538
xref: Reference/CAS 56-65-5
xref: Reference/ChemSpider 5742
xref: Reference/BioCyc ATP
xref: Reference/KEGG Compound C00002
chemical formula: C10H16N5O13P3
molecular weight: 506.99576
structure: ChemicalStructure/PW C000414

ReactionCatalysis822212
type: Catalysis
controller: tagatose-1,6-bisphosphate aldolase 1
controlled: 4.1.2.40
control type: ACTIVATION

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C040945/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-tagatofuranose 6-phosphate
stoichiometric coefficient: 1.0

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16761
type: UnificationXref
id: CHEBI:16761
db: ChEBI

4.1.2.40
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040946/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000869/Stoichiometry/1.0
right: Dihydroxyacetone phosphate
right: D-Glyceraldehyde 3-phosphate
spontaneous: false
EC number: 4.1.2.40
left: D-Tagatofuranose 1,6-bisphosphate
name: D-Tagatofuranose 1,6-bisphosphate → D-Glyceraldehyde 3-phosphate + Dihydroxyacetone phosphate
conversion direction: LEFT_TO_RIGHT

2.7.1.11
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000414/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040945/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040946/Stoichiometry/1.0
right: Adenosine diphosphate
right: Hydrogen Ion
right: D-Tagatofuranose 1,6-bisphosphate
spontaneous: false
EC number: 2.7.1.11
left: D-tagatofuranose 6-phosphate
left: Adenosine triphosphate
name: Adenosine triphosphate + D-tagatofuranose 6-phosphate → Adenosine diphosphate + D-Tagatofuranose 1,6-bisphosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000164
type: ChemicalStructure
structure format: SMILES
structure data: CC(=O)C(O)=O

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

ReactionCatalysis822210
type: Catalysis
controller: 6-phosphofructokinase II
controlled: 2.7.1.11
control type: ACTIVATION

ReactionCatalysis822211
type: Catalysis
controller: tagatose-1,6-bisphosphate aldolase 2
controlled: 4.1.2.40
control type: ACTIVATION

Protein/61529 Inner Membrane/Stoichiometry/2.0
type: Stoichiometry
physical entity: PTS system Galactitol-specific IIC component
stoichiometric coefficient: 2.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

Transporter, major facilitator family protein
type: Protein
entity reference: Transporter, major facilitator family protein

D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit
type: Protein
entity reference: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit

Phosphofructokinase
type: Protein
entity reference: Phosphofructokinase

ChemicalStructure/PW C040943
type: ChemicalStructure
structure format: SMILES
structure data: OCC(O)C(O)CC(=O)C([O-])=O

Reference/ChemSpider 5800
type: UnificationXref
id: 5800
db: ChemSpider

ChemicalStructure/PW C040946
type: ChemicalStructure
structure format: SMILES

ChemicalStructure/PW C040945
type: ChemicalStructure
structure format: SMILES
structure data: OCC1(O)OC(COP([O-])([O-])=O)C(O)C1O

ChemicalStructure/PW C040944
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP([O-])([O-])=O)C(O)CC(=O)C([O-])=O

Hafnia alvei ATCC 51873
type: BioSource
xref: Reference/TAXONOMY 1002364

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Periplasmic Space
type: CellularLocationVocabulary
xref: Reference/GENE ONTOLOGY GO 0005620

Reference/PubChem-compound 729
type: UnificationXref
id: 729
db: PubChem-compound

Reference/UniProt G9Y5M5
type: UnificationXref
id: G9Y5M5
db: UniProt

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 32816
type: UnificationXref
id: CHEBI:32816
db: ChEBI

Putative L-iditol 2-dehydrogenase
type: Protein
entity reference: Putative L-iditol 2-dehydrogenase

2-dehydro-3-deoxy-6-phosphogalactonate aldolase
type: Protein
entity reference: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase

2-dehydro-3-deoxygalactonokinase
type: Protein
entity reference: 2-dehydro-3-deoxygalactonokinase

Starvation-sensing protein RspA
type: Protein
entity reference: Starvation-sensing protein RspA

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/BioCyc PYRUVATE
type: UnificationXref
id: PYRUVATE
db: BioCyc

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 58-64-0
type: UnificationXref
id: 58-64-0
db: CAS

Reference/KEGG Compound C00880
type: UnificationXref
id: C00880
db: KEGG Compound

ChemicalStructure/PW C000414
type: ChemicalStructure
structure format: SMILES

Putative galactitol-specific phosphotransferase enzyme IIB component
type: Protein
cellular location: Inner Membrane
entity reference: Putative galactitol-specific phosphotransferase enzyme IIB component

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/CAS 2255-14-3
type: UnificationXref
id: 2255-14-3
db: CAS

Compound/PW C000869/Stoichiometry/1.0
type: Stoichiometry
physical entity: D-Glyceraldehyde 3-phosphate
stoichiometric coefficient: 1.0

Reference/PubChem-compound 128869
type: UnificationXref
id: 128869
db: PubChem-compound

Galactose 1-phosphate
type: SmallMolecule
cellular location: Inner Membrane
entity reference: Galactose 1-phosphate

ChemicalStructure/PW C000869
type: ChemicalStructure
structure format: SMILES
structure data: OC(COP(O)(O)=O)C=O

Reference/UniProt G9Y9G7
type: UnificationXref
id: G9Y9G7
db: UniProt

ChemicalStructure/PW C000504
type: ChemicalStructure
structure format: SMILES

tagatose-bisphosphate aldolase
type: ProteinReference
xref: Reference/UniProt G9Y353

Protein/61526/Stoichiometry/2.0
type: Stoichiometry
physical entity: Phosphofructokinase
stoichiometric coefficient: 2.0

Reference/UniProt G9Y9G6
type: UnificationXref
id: G9Y9G6
db: UniProt

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

PTS system Galactitol-specific IIC component
type: Protein
cellular location: Inner Membrane
entity reference: PTS system Galactitol-specific IIC component

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

Reference/PubChem-compound 1060
type: UnificationXref
id: 1060
db: PubChem-compound

Reference/BioCyc GAP
type: UnificationXref
id: GAP
db: BioCyc

Reference/CAS 576-36-3
type: UnificationXref
id: 576-36-3
db: CAS

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Hydrogen Ion
type: SmallMolecule
cellular location: Periplasmic Space
entity reference: Hydrogen Ion

Reference/KEGG Compound C00661
type: UnificationXref
id: C00661
db: KEGG Compound

Reference/ChEBI CHEBI 57989
type: UnificationXref
id: CHEBI:57989
db: ChEBI

Compound/PW C000069 Inner Membrane/Stoichiometry/1.0
type: Stoichiometry
physical entity: Galactitol
stoichiometric coefficient: 1.0

Compound/PW C040034 Periplasmic Space/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Reference/HMDB HMDB0000645
type: UnificationXref
id: HMDB0000645
db: HMDB