CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z))
type: SmallMolecule
entity reference: CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z))

Reference/ChemSpider 17215925
type: UnificationXref
id: 17215925
db: ChemSpider

Reference/KEGG Compound C02737
type: UnificationXref
id: C02737
db: KEGG Compound

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Compound/PW C102484/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(14:1(9Z)/14:1(9Z))
stoichiometric coefficient: 1.0

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-ETHANOLAMINE
db: BioCyc

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

ChemicalStructure/PW C102484
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C004903/Stoichiometry/1.0
type: Stoichiometry
physical entity: PE(14:1(9Z)/14:1(9Z))
stoichiometric coefficient: 1.0

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Compound/PW C003089/Stoichiometry/1.0
type: Stoichiometry
physical entity: DG(14:1(9Z)/14:1(9Z)/0:0)
stoichiometric coefficient: 1.0

Phosphatidylglycerophosphatase A
type: Protein
entity reference: Phosphatidylglycerophosphatase A

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Reference/ChEBI CHEBI 17115
type: UnificationXref
id: CHEBI:17115
db: ChEBI

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

1-acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P26647

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate
name: SubPathwayOutput

Reference/UniProt P18200
type: UnificationXref
id: P18200
db: UniProt

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

ChemicalStructure/PW C045379
type: ChemicalStructure
structure format: SMILES

CDP-diacylglycerol--serine O-phosphatidyltransferase
type: Protein
entity reference: CDP-diacylglycerol--serine O-phosphatidyltransferase

ReactionCatalysis3084
type: Catalysis
controller: glycerol-3-phosphate dehydrogenase (aerobic)
controlled: 1.1.1.94
control type: ACTIVATION

Reference/CAS 53-59-8
type: UnificationXref
id: 53-59-8
db: CAS

Reference/PubChem-compound 700
type: UnificationXref
id: 700
db: PubChem-compound

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

ChemicalStructure/PW C004903
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCCCCC\C=C/CCCC)(COP(O)(=O)OCCN)OC(=O)CCCCCCC\C=C/CCCC

Reference/ChEBI CHEBI 16474
type: UnificationXref
id: CHEBI:16474
db: ChEBI

Compound/PW C281874/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z))
stoichiometric coefficient: 1.0

DG(14:1(9Z)/14:1(9Z)/0:0)
type: SmallMoleculeReference
xref: Reference/BioCyc DIACYLGLYCEROL
xref: Reference/PubChem-compound 53477973
xref: Reference/HMDB HMDB0007038
xref: Reference/KEGG Compound C00165
xref: Reference/ChemSpider 24765872
xref: Reference/ChEBI CHEBI 84702
chemical formula: C31H56O5
molecular weight: 508.41278
structure: ChemicalStructure/PW C003089

Reference/UniProt P26647
type: UnificationXref
id: P26647
db: UniProt

Reference/ChemSpider 274
type: UnificationXref
id: 274
db: ChemSpider

Reference/ChemSpider 5736
type: UnificationXref
id: 5736
db: ChemSpider

Reference/PathWhiz PW759915
type: UnificationXref
id: PW759915
db: PathWhiz

Reference/ChEBI CHEBI 18303
type: UnificationXref
id: CHEBI:18303
db: ChEBI

Reaction2140335
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045379/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003089/Stoichiometry/1.0
right: CDP-DG(14:1(9Z)/14:1(9Z))
right: Pyrophosphate
spontaneous: false
left: Cytidine triphosphate
left: Hydrogen Ion
left: DG(14:1(9Z)/14:1(9Z)/0:0)
name: Cytidine triphosphate + DG(14:1(9Z)/14:1(9Z)/0:0) + Hydrogen Ion → CDP-DG(14:1(9Z)/14:1(9Z)) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Reaction2140334
type: BiochemicalReaction
participant stoichiometry: Compound/PW C055365/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C282392/Stoichiometry/1.0
participant stoichiometry: Compound/PW C003089/Stoichiometry/1.0
right: Coenzyme A
right: DG(14:1(9Z)/14:1(9Z)/0:0)
spontaneous: false
left: Tetradecenoic-CoA(Δ9)
left: LysoPA(14:1(9Z)/0:0)
name: LysoPA(14:1(9Z)/0:0) + Tetradecenoic-CoA(Δ9) → Coenzyme A + DG(14:1(9Z)/14:1(9Z)/0:0)
conversion direction: LEFT_TO_RIGHT

NADPH
type: SmallMolecule
entity reference: NADPH

Reaction2140339
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102484/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102463/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(14:1(9Z)/14:1(9Z))
right: Phosphate
spontaneous: false
left: Water
left: PGP(14:1(9Z)/14:1(9Z))
name: PGP(14:1(9Z)/14:1(9Z)) + Water → PG(14:1(9Z)/14:1(9Z)) + Phosphate
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 16000
type: UnificationXref
id: CHEBI:16000
db: ChEBI

Reaction2140338
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102463/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045379/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: Hydrogen Ion
right: PGP(14:1(9Z)/14:1(9Z))
spontaneous: false
left: CDP-DG(14:1(9Z)/14:1(9Z))
left: Glycerol 3-phosphate
name: CDP-DG(14:1(9Z)/14:1(9Z)) + Glycerol 3-phosphate → Cytidine monophosphate + Hydrogen Ion + PGP(14:1(9Z)/14:1(9Z))
conversion direction: LEFT_TO_RIGHT

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/BioCyc SER
type: UnificationXref
id: SER
db: BioCyc

Reaction2140337
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001316/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004903/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007872/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Carbon dioxide
right: PE(14:1(9Z)/14:1(9Z))
spontaneous: false
left: Hydrogen Ion
left: PS(14:1(9Z)/14:1(9Z))
name: Hydrogen Ion + PS(14:1(9Z)/14:1(9Z)) → Carbon dioxide + PE(14:1(9Z)/14:1(9Z))
conversion direction: LEFT_TO_RIGHT

Reaction2140336
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C007872/Stoichiometry/1.0
participant stoichiometry: Compound/PW C045379/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000120/Stoichiometry/1.0
right: Cytidine monophosphate
right: Hydrogen Ion
right: PS(14:1(9Z)/14:1(9Z))
spontaneous: false
left: CDP-DG(14:1(9Z)/14:1(9Z))
left: L-Serine
name: CDP-DG(14:1(9Z)/14:1(9Z)) + L-Serine → Cytidine monophosphate + Hydrogen Ion + PS(14:1(9Z)/14:1(9Z))
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

NADP
type: SmallMolecule
entity reference: NADP

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

NADPH
type: SmallMoleculeReference
xref: Reference/CAS 53-57-6
xref: Reference/HMDB HMDB0000221
xref: Reference/PubChem-compound 22833512
xref: Reference/BioCyc NADPH
xref: Reference/ChemSpider 17215925
xref: Reference/KEGG Compound C00005
xref: Reference/ChEBI CHEBI 16474
chemical formula: C21H30N7O17P3
molecular weight: 745.0911
structure: ChemicalStructure/PW C000146

ChemicalStructure/PW C007872
type: ChemicalStructure
structure format: SMILES

Tetradecenoic-CoA(Δ9)
type: SmallMolecule
entity reference: Tetradecenoic-CoA(Δ9)

NADP
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00006
xref: Reference/CAS 53-59-8
xref: Reference/BioCyc NAD(P)
xref: Reference/HMDB HMDB0000217
xref: Reference/ChEBI CHEBI 18009
xref: Reference/PubChem-compound 5886
xref: Reference/ChemSpider 5675
chemical formula: C21H28N7O17P3
molecular weight: 743.07544
structure: ChemicalStructure/PW C000143

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Glycerol-3-phosphate acyltransferase
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Compound/PW C102463/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(14:1(9Z)/14:1(9Z))
stoichiometric coefficient: 1.0

Tetradecenoic-CoA(Δ9)
type: SmallMoleculeReference

Compound/PW C000146/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADPH
stoichiometric coefficient: 1.0

Reference/BioCyc NADPH
type: UnificationXref
id: NADPH
db: BioCyc

Compound/PW C055365/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPA(14:1(9Z)/0:0)
stoichiometric coefficient: 1.0

CDP-DG(14:1(9Z)/14:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C40H69N3O15P2
molecular weight: 893.4204
structure: ChemicalStructure/PW C045379

Reference/ChEBI CHEBI 16975
type: UnificationXref
id: CHEBI:16975
db: ChEBI

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/PathWhiz PW000785
type: UnificationXref
id: PW000785
db: PathWhiz

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: ProteinReference
xref: Reference/UniProt P0A6S7

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

Reference/KEGG Compound C00350
type: UnificationXref
id: C00350
db: KEGG Compound

ChemicalStructure/PW C055365
type: ChemicalStructure
structure format: SMILES
structure data: CCCC\C=C/CCCCCCCC(=O)OCC(O)COP(O)(O)=O

1.1.1.94
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000146/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000143/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NADP
right: Glycerol 3-phosphate
spontaneous: false
EC number: 1.1.1.94
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
left: NADPH
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADPH → Glycerol 3-phosphate + NADP
conversion direction: LEFT_TO_RIGHT

Ethanolamine
type: SmallMolecule
entity reference: Ethanolamine

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: Protein
entity reference: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Phosphatidate cytidylyltransferase
type: Protein
entity reference: Phosphatidate cytidylyltransferase

Phosphatidylglycerophosphatase A
type: ProteinReference
xref: Reference/UniProt P18200

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

ChemicalStructure/PW C003089
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@](CO)(COC(=O)CCCCCCC\C=C/CCCC)OC(=O)CCCCCCC\C=C/CCCC

Reference/HMDB HMDB0000217
type: UnificationXref
id: HMDB0000217
db: HMDB

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

Reference/CAS 124-38-9
type: UnificationXref
id: 124-38-9
db: CAS

Reference/HMDB HMDB0008855
type: UnificationXref
id: HMDB0008855
db: HMDB

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00006
type: UnificationXref
id: C00006
db: KEGG Compound

Reference/PubChem-compound 53477973
type: UnificationXref
id: 53477973
db: PubChem-compound

PG(14:1(9Z)/14:1(9Z))
type: SmallMoleculeReference
chemical formula: C34H63O10P
molecular weight: 662.4159
structure: ChemicalStructure/PW C102484

CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z))
type: SmallMoleculeReference
chemical formula: C79H145O12P
molecular weight: 1317.0474

Reference/ChEBI CHEBI 18009
type: UnificationXref
id: CHEBI:18009
db: ChEBI

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C00005
type: UnificationXref
id: C00005
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

ChemicalStructure/PW C000143
type: ChemicalStructure
structure format: SMILES

Reference/HMDB HMDB0000221
type: UnificationXref
id: HMDB0000221
db: HMDB

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

CDP-diacylglycerol--serine O-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt P23830

ChemicalStructure/PW C000146
type: ChemicalStructure
structure format: SMILES

Reference/ChemSpider 13835336
type: UnificationXref
id: 13835336
db: ChemSpider

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

cardiolipin synthase c
type: Protein
entity reference: cardiolipin synthase c

Compound/PW C045379/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(14:1(9Z)/14:1(9Z))
stoichiometric coefficient: 1.0

Compound/PW C000120/Stoichiometry/1.0
type: Stoichiometry
physical entity: L-Serine
stoichiometric coefficient: 1.0

Reference/CAS 53-57-6
type: UnificationXref
id: 53-57-6
db: CAS

Glycolysis and Pyruvate Dehydrogenase
type: Pathway
pathway order: SubPathwayInteractionSteps/SubPathway836799
pathway component: SubPathwayInteraction836799
xref: Reference/PathWhiz PW000785
xref: Reference/SMPDB SMP0000807
name: SubPathway

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

Reference/KEGG Compound C00011
type: UnificationXref
id: C00011
db: KEGG Compound

ChemicalStructure/PW C001316
type: ChemicalStructure
structure format: SMILES
structure data: O=C=O

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/PubChem-compound 52924935
type: UnificationXref
id: 52924935
db: PubChem-compound

Reference/PubChem-compound 5951
type: UnificationXref
id: 5951
db: PubChem-compound

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Compound/PW C000096/Stoichiometry/1.0
type: Stoichiometry
physical entity: Ethanolamine
stoichiometric coefficient: 1.0

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

Reference/BioCyc NAD(P)
type: UnificationXref
id: NAD(P)
db: BioCyc

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

PGP(14:1(9Z)/14:1(9Z))
type: SmallMolecule
entity reference: PGP(14:1(9Z)/14:1(9Z))

Reference/UniProt P0A8K1
type: UnificationXref
id: P0A8K1
db: UniProt

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Phospholipid Biosynthesis CL(14:1(9Z)/14:1(9Z)/18:0/22:1(11Z))
type: Pathway
pathway order: PathwayEnzymeReaction/9685970
pathway order: PathwayEnzymeReaction/9685971
pathway order: PathwayEnzymeReaction/9685974
pathway order: PathwayEnzymeReaction/9685975
pathway order: PathwayEnzymeReaction/9685972
pathway order: PathwayEnzymeReaction/9685973
pathway order: PathwaySubPathway/836799
pathway order: PathwayEnzymeReaction/9685976
pathway order: PathwayEnzymeReaction/9685977
pathway order: PathwayEnzymeReaction/9685969
pathway component: Glycolysis and Pyruvate Dehydrogenase
pathway component: ReactionCatalysis3084
pathway component: ReactionCatalysis1974378
pathway component: ReactionCatalysis1974379
pathway component: ReactionCatalysis1974376
pathway component: ReactionCatalysis1974377
pathway component: Reaction2140335
pathway component: Reaction2140334
pathway component: Reaction2140003
pathway component: Reaction2140339
pathway component: Reaction2140338
pathway component: Reaction2140337
pathway component: Reaction2140336
pathway component: ReactionCatalysis1974380
pathway component: 1.1.1.94
pathway component: ReactionCatalysis3789
pathway component: Reaction2140340
pathway component: ReactionCatalysis3792
pathway component: ReactionCatalysis3793
xref: Reference/PathWhiz PW759915
xref: Reference/SMPDB SMP0722136
organism: Escherichia coli

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

PGP(14:1(9Z)/14:1(9Z))
type: SmallMoleculeReference
chemical formula: C34H64O13P2
molecular weight: 742.3822
structure: ChemicalStructure/PW C102463

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Reference/HMDB HMDB0012342
type: UnificationXref
id: HMDB0012342
db: HMDB

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P0A7A7

ChemicalStructure/PW C000120
type: ChemicalStructure
structure format: SMILES
structure data: N[C@@H](CO)C(O)=O

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Compound/PW C000143/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADP
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 84702
type: UnificationXref
id: CHEBI:84702
db: ChEBI

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

Phosphatidylserine decarboxylase proenzyme
type: Protein
entity reference: Phosphatidylserine decarboxylase proenzyme

Reference/BioCyc DIACYLGLYCEROL
type: UnificationXref
id: DIACYLGLYCEROL
db: BioCyc

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/SMPDB SMP0000807
type: UnificationXref
id: SMP0000807
db: SMPDB

PE(14:1(9Z)/14:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChemSpider 24768360
xref: Reference/BioCyc L-1-PHOSPHATIDYL-ETHANOLAMINE
xref: Reference/HMDB HMDB0008855
xref: Reference/KEGG Compound C00350
xref: Reference/PubChem-compound 52924935
chemical formula: C33H62NO8P
molecular weight: 631.4213
structure: ChemicalStructure/PW C004903

Compound/PW C282392/Stoichiometry/1.0
type: Stoichiometry
physical entity: Tetradecenoic-CoA(Δ9)
stoichiometric coefficient: 1.0

CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
type: ProteinReference
xref: Reference/UniProt P0ABF8

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

PG(14:1(9Z)/14:1(9Z))
type: SmallMolecule
entity reference: PG(14:1(9Z)/14:1(9Z))

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Phosphatidylglycerophosphatase B
type: Protein
entity reference: Phosphatidylglycerophosphatase B

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/KEGG Compound C00165
type: UnificationXref
id: C00165
db: KEGG Compound

Reference/ChemSpider 5675
type: UnificationXref
id: 5675
db: ChemSpider

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

cardiolipin synthase c
type: ProteinReference
xref: Reference/UniProt P75919

Phosphatidate cytidylyltransferase
type: ProteinReference
xref: Reference/UniProt P0ABG1

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

PS(14:1(9Z)/14:1(9Z))
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 18303
xref: Reference/ChemSpider 13628254
xref: Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
xref: Reference/KEGG Compound C02737
xref: Reference/PubChem-compound 52926026
xref: Reference/HMDB HMDB0012342
chemical formula: C34H62NO10P
molecular weight: 675.41113
structure: ChemicalStructure/PW C007872

Reference/HMDB HMDB0000149
type: UnificationXref
id: HMDB0000149
db: HMDB

PS(14:1(9Z)/14:1(9Z))
type: SmallMolecule
entity reference: PS(14:1(9Z)/14:1(9Z))

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

Compound/PW C001316/Stoichiometry/1.0
type: Stoichiometry
physical entity: Carbon dioxide
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Reference/UniProt P0A6S7
type: UnificationXref
id: P0A6S7
db: UniProt

Reference/BioCyc ETHANOL-AMINE
type: UnificationXref
id: ETHANOL-AMINE
db: BioCyc

Ethanolamine
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0000149
xref: Reference/ChemSpider 13835336
xref: Reference/PubChem-compound 700
xref: Reference/CAS 141-43-5
xref: Reference/BioCyc ETHANOL-AMINE
xref: Reference/ChEBI CHEBI 16000
xref: Reference/KEGG Compound C00189
chemical formula: C2H7NO
molecular weight: 61.052765
structure: ChemicalStructure/PW C000096

Reference/ChemSpider 13628254
type: UnificationXref
id: 13628254
db: ChemSpider

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

CDP-DG(14:1(9Z)/14:1(9Z))
type: SmallMolecule
entity reference: CDP-DG(14:1(9Z)/14:1(9Z))

Reference/ChEBI CHEBI 16526
type: UnificationXref
id: CHEBI:16526
db: ChEBI

PE(14:1(9Z)/14:1(9Z))
type: SmallMolecule
entity reference: PE(14:1(9Z)/14:1(9Z))

Reference/KEGG Compound C00065
type: UnificationXref
id: C00065
db: KEGG Compound

Reference/SMPDB SMP0722136
type: UnificationXref
id: SMP0722136
db: SMPDB

Reference/KEGG Compound C00189
type: UnificationXref
id: C00189
db: KEGG Compound

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

Phosphatidylserine decarboxylase proenzyme
type: ProteinReference
xref: Reference/UniProt P0A8K1

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

glycerol-3-phosphate dehydrogenase (aerobic)
type: Complex
component stoichiometry: Protein/6009/Stoichiometry/2.0
component: Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Carbon dioxide
type: SmallMoleculeReference
xref: Reference/PubChem-compound 280
xref: Reference/ChEBI CHEBI 16526
xref: Reference/ChemSpider 274
xref: Reference/HMDB HMDB0001967
xref: Reference/CAS 124-38-9
xref: Reference/KEGG Compound C00011
chemical formula: CO2
molecular weight: 43.98983
structure: ChemicalStructure/PW C001316

Phosphate
type: SmallMolecule
entity reference: Phosphate

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

ReactionCatalysis1974380
type: Catalysis
controller: cardiolipin synthase c
controlled: Reaction2140340
control type: ACTIVATION

ReactionCatalysis3789
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase
controlled: Reaction2140003
control type: ACTIVATION

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Phosphatidylglycerophosphatase B
type: ProteinReference
xref: Reference/UniProt P0A924

ChemicalStructure/PW C000096
type: ChemicalStructure
structure format: SMILES
structure data: NCCO

Reference/UniProt P23830
type: UnificationXref
id: P23830
db: UniProt

1-acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Reaction2140340
type: BiochemicalReaction
participant stoichiometry: Compound/PW C281874/Stoichiometry/1.0
participant stoichiometry: Compound/PW C102484/Stoichiometry/1.0
participant stoichiometry: Compound/PW C004903/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000096/Stoichiometry/1.0
right: Ethanolamine
right: CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z))
spontaneous: false
left: PE(14:1(9Z)/14:1(9Z))
left: PG(14:1(9Z)/14:1(9Z))
name: PE(14:1(9Z)/14:1(9Z)) + PG(14:1(9Z)/14:1(9Z)) → CL(19:1(9Z)/18:1(9Z)/19:1(9Z)/18:1(9Z)) + Ethanolamine
conversion direction: LEFT_TO_RIGHT

DG(14:1(9Z)/14:1(9Z)/0:0)
type: SmallMolecule
entity reference: DG(14:1(9Z)/14:1(9Z)/0:0)

Reference/UniProt P0A924
type: UnificationXref
id: P0A924
db: UniProt

Reference/PubChem-compound 52926026
type: UnificationXref
id: 52926026
db: PubChem-compound

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

ReactionCatalysis1974378
type: Catalysis
controller: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase
controlled: Reaction2140338
control type: ACTIVATION

Reference/BioCyc L-1-PHOSPHATIDYL-SERINE
type: UnificationXref
id: L-1-PHOSPHATIDYL-SERINE
db: BioCyc

ReactionCatalysis1974379
type: Catalysis
controller: phosphatidylglycerophosphatase
controlled: Reaction2140339
control type: ACTIVATION

ReactionCatalysis1974376
type: Catalysis
controller: CDP-diacylglycerol--serine O-phosphatidyltransferase
controlled: Reaction2140336
control type: ACTIVATION

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

ReactionCatalysis1974377
type: Catalysis
controller: Phosphatidylserine decarboxylase proenzyme
controlled: Reaction2140337
control type: ACTIVATION

Reference/CAS 56-45-1
type: UnificationXref
id: 56-45-1
db: CAS

Reference/PubChem-compound 5886
type: UnificationXref
id: 5886
db: PubChem-compound

Reference/ChemSpider 24765872
type: UnificationXref
id: 24765872
db: ChemSpider

Compound/PW C007872/Stoichiometry/1.0
type: Stoichiometry
physical entity: PS(14:1(9Z)/14:1(9Z))
stoichiometric coefficient: 1.0

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

Reference/PubChem-compound 280
type: UnificationXref
id: 280
db: PubChem-compound

phosphatidylglycerophosphatase
type: Complex
component: Phosphatidylglycerophosphatase B
component: Phosphatidylglycerophosphatase A

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

L-Serine
type: SmallMolecule
entity reference: L-Serine

ReactionCatalysis3792
type: Catalysis
controller: 1-acyl-sn-glycerol-3-phosphate acyltransferase
controlled: Reaction2140334
control type: ACTIVATION

ReactionCatalysis3793
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: Reaction2140335
control type: ACTIVATION

L-Serine
type: SmallMoleculeReference
xref: Reference/ChemSpider 5736
xref: Reference/ChEBI CHEBI 17115
xref: Reference/CAS 56-45-1
xref: Reference/KEGG Compound C00065
xref: Reference/PubChem-compound 5951
xref: Reference/HMDB HMDB0000187
xref: Reference/BioCyc SER
chemical formula: C3H7NO3
molecular weight: 105.042595
structure: ChemicalStructure/PW C000120

Reference/HMDB HMDB0000187
type: UnificationXref
id: HMDB0000187
db: HMDB

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

Reference/UniProt P0ABG1
type: UnificationXref
id: P0ABG1
db: UniProt

Reference/UniProt P0A7A7
type: UnificationXref
id: P0A7A7
db: UniProt

Reaction2140003
type: BiochemicalReaction
participant stoichiometry: Compound/PW C055365/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C282392/Stoichiometry/1.0
right: Coenzyme A
right: LysoPA(14:1(9Z)/0:0)
spontaneous: false
left: Tetradecenoic-CoA(Δ9)
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Tetradecenoic-CoA(Δ9) → Coenzyme A + LysoPA(14:1(9Z)/0:0)
conversion direction: LEFT_TO_RIGHT

LysoPA(14:1(9Z)/0:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 16975
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
chemical formula: C17H33O7P
molecular weight: 380.19638
structure: ChemicalStructure/PW C055365

Reference/PubChem-compound 22833512
type: UnificationXref
id: 22833512
db: PubChem-compound

Reference/UniProt P0ABF8
type: UnificationXref
id: P0ABF8
db: UniProt

Reference/ChemSpider 24768360
type: UnificationXref
id: 24768360
db: ChemSpider

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

ChemicalStructure/PW C102463
type: ChemicalStructure
structure format: SMILES

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

Reference/CAS 141-43-5
type: UnificationXref
id: 141-43-5
db: CAS

Carbon dioxide
type: SmallMolecule
entity reference: Carbon dioxide

Reference/HMDB HMDB0001967
type: UnificationXref
id: HMDB0001967
db: HMDB

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(P)+]

LysoPA(14:1(9Z)/0:0)
type: SmallMolecule
entity reference: LysoPA(14:1(9Z)/0:0)

Reference/UniProt P75919
type: UnificationXref
id: P75919
db: UniProt

Protein/6009/Stoichiometry/2.0
type: Stoichiometry
physical entity: Glycerol-3-phosphate dehydrogenase [NAD(P)+]
stoichiometric coefficient: 2.0

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Reference/HMDB HMDB0007038
type: UnificationXref
id: HMDB0007038
db: HMDB

SubPathwayInteraction836799
type: Interaction
name: SubPathway836799Reaction
name: SubPathwayReaction
participant: Dihydroxyacetone phosphate

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O