PG(12:0/12:0)
type: SmallMolecule
entity reference: PG(12:0/12:0)

Reference/ChemSpider 937
type: UnificationXref
id: 937
db: ChemSpider

Reference/PubChem-compound 439162
type: UnificationXref
id: 439162
db: PubChem-compound

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL-P
db: BioCyc

Compound/PW C044232/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(12:0/12:0)
stoichiometric coefficient: 1.0

Capric acid
type: SmallMoleculeReference
xref: Reference/PubChem-compound 2969
xref: Reference/BioCyc 3-OXODODECANOATE
xref: Reference/ChEBI CHEBI 30813
xref: Reference/HMDB HMDB0000511
xref: Reference/ChemSpider 2863
xref: Reference/KEGG Compound C01571
xref: Reference/CAS 334-48-5
chemical formula: C10H20O2
molecular weight: 172.14633
structure: ChemicalStructure/PW C000391

NADH
type: SmallMolecule
entity reference: NADH

Cytidine triphosphate
type: SmallMolecule
entity reference: Cytidine triphosphate

Reference/PubChem-compound 439153
type: UnificationXref
id: 439153
db: PubChem-compound

ChemicalStructure/PW C001420
type: ChemicalStructure
structure format: SMILES
structure data: O

Reference/HMDB HMDB0000095
type: UnificationXref
id: HMDB0000095
db: HMDB

Cardiolipin Biosynthesis via MLCL(0:0/12:0/12:0/28:1(11Z))
type: Pathway
pathway order: PathwayEnzymeReaction/9748910
pathway order: PathwayEnzymeReaction/9748911
pathway order: PathwayEnzymeReaction/9748912
pathway order: PathwayEnzymeReaction/9748913
pathway order: PathwayEnzymeReaction/9748914
pathway order: PathwayEnzymeReaction/9748915
pathway order: PathwayEnzymeReaction/9748916
pathway order: PathwayEnzymeReaction/9748908
pathway order: PathwayEnzymeReaction/9748909
pathway component: Reaction180887
pathway component: Reaction180886
pathway component: ReactionCatalysis170600
pathway component: ReactionCatalysis170896
pathway component: Reaction2143786
pathway component: 3.5.1.-
pathway component: Reaction2143079
pathway component: 2.7.8.-
pathway component: 2.7.8.5
pathway component: 2.7.7.41
pathway component: 2.3.1.23
pathway component: ReactionCatalysis2174637
pathway component: ReactionCatalysis2174636
pathway component: ReactionCatalysis170895
pathway component: ReactionCatalysis2174638
pathway component: ReactionCatalysis2174633
pathway component: ReactionCatalysis2174634
pathway component: ReactionCatalysis2174630
xref: Reference/SMPDB SMP0724560
xref: Reference/PathWhiz PW762339
organism: Escherichia coli

Pyrophosphate
type: SmallMolecule
entity reference: Pyrophosphate

Compound/PW C040034/Stoichiometry/1.0
type: Stoichiometry
physical entity: Hydrogen Ion
stoichiometric coefficient: 1.0

Phosphatidylglycerophosphatase A
type: Protein
entity reference: Phosphatidylglycerophosphatase A

CDP-DG(28:1(11Z)/28:1(11Z))
type: SmallMoleculeReference
chemical formula: C68H125N3O15P2
molecular weight: 1285.8586

Lauroyl-CoA
type: SmallMoleculeReference
xref: Reference/BioCyc LAUROYLCOA-CPD
xref: Reference/KEGG Compound C01832
xref: Reference/ChEBI CHEBI 15521
xref: Reference/HMDB HMDB0003571
xref: Reference/CAS 6244-92-4
xref: Reference/ChemSpider 145018
xref: Reference/PubChem-compound 165436
chemical formula: C33H58N7O17P3S
molecular weight: 949.2823
structure: ChemicalStructure/PW C001928

Reference/PubChem-compound 6131
type: UnificationXref
id: 6131
db: PubChem-compound

Compound/PW C000064/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine monophosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C043864
type: ChemicalStructure
structure format: SMILES

NAD
type: SmallMolecule
entity reference: NAD

ReactionCatalysis170600
type: Catalysis
controller: phosphatidylglycerophosphatase
controlled: Reaction2143786
control type: ACTIVATION

1-acyl-sn-glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P26647

Reference/KEGG Compound C00681
type: UnificationXref
id: C00681
db: KEGG Compound

PC(12:0/12:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00157
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
chemical formula: C32H64NO8P
molecular weight: 621.43695
structure: ChemicalStructure/PW C055670

Dihydroxyacetone phosphate
type: SmallMolecule
entity reference: Dihydroxyacetone phosphate

Reference/BioCyc 3-OXODODECANOATE
type: UnificationXref
id: 3-OXODODECANOATE
db: BioCyc

Reference/UniProt P18200
type: UnificationXref
id: P18200
db: UniProt

Reference/PubChem-compound 6816
type: UnificationXref
id: 6816
db: PubChem-compound

Dihydroxyacetone phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
xref: Reference/PubChem-compound 668
xref: Reference/ChEBI CHEBI 16108
xref: Reference/KEGG Compound C00111
xref: Reference/CAS 57-04-5
xref: Reference/ChemSpider 648
xref: Reference/HMDB HMDB0001473
chemical formula: C3H7O6P
molecular weight: 169.99803
structure: ChemicalStructure/PW C001134

Putative cardiolipin synthase ybhO
type: Protein
entity reference: Putative cardiolipin synthase ybhO

Reference/ChemSpider 559142
type: UnificationXref
id: 559142
db: ChemSpider

Reference/ChEBI CHEBI 15846
type: UnificationXref
id: CHEBI:15846
db: ChEBI

Probable HTH-type transcriptional regulator LrhA
type: Protein
entity reference: Probable HTH-type transcriptional regulator LrhA

Phosphatidylserine synthase
type: Protein
entity reference: Phosphatidylserine synthase

Lauroyl-CoA
type: SmallMolecule
entity reference: Lauroyl-CoA

PC(12:0/12:0)
type: SmallMolecule
entity reference: PC(12:0/12:0)

Reference/PubChem-compound 1038
type: UnificationXref
id: 1038
db: PubChem-compound

M48 family metalloprotease
type: Protein
entity reference: M48 family metalloprotease

Alpha/beta hydrolase
type: Protein
entity reference: Alpha/beta hydrolase

Capric acid
type: SmallMolecule
entity reference: Capric acid

Reference/UniProt P26647
type: UnificationXref
id: P26647
db: UniProt

ReactionCatalysis2174637
type: Catalysis
controller: M48 family metalloprotease
controlled: 2.3.1.23
control type: ACTIVATION

ReactionCatalysis2174636
type: Catalysis
controller: cardiolipin synthase
controlled: 2.7.8.-
control type: ACTIVATION

ReactionCatalysis2174638
type: Catalysis
controller: Alpha/beta hydrolase
controlled: 3.5.1.-
control type: ACTIVATION

ReactionCatalysis2174633
type: Catalysis
controller: Phosphatidate cytidylyltransferase
controlled: 2.7.7.41
control type: ACTIVATION

MLCL(0:0/12:0/12:0/28:1(11Z))
type: SmallMolecule
entity reference: MLCL(0:0/12:0/12:0/28:1(11Z))

ReactionCatalysis2174634
type: Catalysis
controller: Phosphatidylserine synthase
controlled: 2.7.8.5
control type: ACTIVATION

Reference/ChEBI CHEBI 62840
type: UnificationXref
id: CHEBI:62840
db: ChEBI

Compound/PW C043864/Stoichiometry/1.0
type: Stoichiometry
physical entity: PGP(10:0/10:0)
stoichiometric coefficient: 1.0

ReactionCatalysis2174630
type: Catalysis
controller: Glycerol-3-phosphate dehydrogenase
controlled: Reaction2143079
control type: ACTIVATION

Reference/ChEBI CHEBI 16908
type: UnificationXref
id: CHEBI:16908
db: ChEBI

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(P)+]

PG(12:0/12:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17517
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
xref: Reference/KEGG Compound C00344
chemical formula: C30H59O10P
molecular weight: 610.3846
structure: ChemicalStructure/PW C041600

Cardiolipin synthase
type: ProteinReference
xref: Reference/UniProt P0A6H8

Phosphate
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00009
xref: Reference/PubChem-compound 1061
xref: Reference/CAS 14265-44-2
xref: Reference/HMDB HMDB0001429
xref: Reference/BioCyc CPD-8587
xref: Reference/ChEBI CHEBI 18367
xref: Reference/ChemSpider 1032
chemical formula: H3O4P
molecular weight: 97.9769
structure: ChemicalStructure/PW C001104

Phosphatidate cytidylyltransferase
type: Protein
entity reference: Phosphatidate cytidylyltransferase

Reference/ChemSpider 1010
type: UnificationXref
id: 1010
db: ChemSpider

Reference/KEGG Compound C00344
type: UnificationXref
id: C00344
db: KEGG Compound

ChemicalStructure/PW C001099
type: ChemicalStructure
structure format: SMILES

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: Protein
entity reference: Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Reference/BioCyc PPI
type: UnificationXref
id: PPI
db: BioCyc

Reference/BioCyc ACYL-SN-GLYCEROL-3P
type: UnificationXref
id: ACYL-SN-GLYCEROL-3P
db: BioCyc

Glycerol-3-phosphate acyltransferase
type: Protein
entity reference: Glycerol-3-phosphate acyltransferase

Reference/CAS 63-37-6
type: UnificationXref
id: 63-37-6
db: CAS

Reference/ChEBI CHEBI 15521
type: UnificationXref
id: CHEBI:15521
db: ChEBI

Phosphatidate cytidylyltransferase
type: Complex
component: Probable HTH-type transcriptional regulator LrhA
component: Phosphatidate cytidylyltransferase

Hydrogen Ion
type: SmallMolecule
entity reference: Hydrogen Ion

Reference/KEGG Compound C00111
type: UnificationXref
id: C00111
db: KEGG Compound

ChemicalStructure/PW C042968
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCCCC(=O)OCC(O)COP(O)(O)=O

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

Reference/CAS 58-68-4
type: UnificationXref
id: 58-68-4
db: CAS

Reference/BioCyc LAUROYLCOA-CPD
type: UnificationXref
id: LAUROYLCOA-CPD
db: BioCyc

Reference/HMDB HMDB0001423
type: UnificationXref
id: HMDB0001423
db: HMDB

Phosphatidylglycerophosphatase A
type: ProteinReference
xref: Reference/UniProt P18200

ChemicalStructure/PW C001104
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(O)=O

Compound/PW C000057/Stoichiometry/1.0
type: Stoichiometry
physical entity: Cytidine triphosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C044232
type: ChemicalStructure
structure format: SMILES

Reference/KEGG Compound C00009
type: UnificationXref
id: C00009
db: KEGG Compound

Reference/KEGG Compound C00001
type: UnificationXref
id: C00001
db: KEGG Compound

Reference/HMDB HMDB0001429
type: UnificationXref
id: HMDB0001429
db: HMDB

Reference/BioCyc CTP
type: UnificationXref
id: CTP
db: BioCyc

Reference/ChEBI CHEBI 18361
type: UnificationXref
id: CHEBI:18361
db: ChEBI

Reference/KEGG Compound C01571
type: UnificationXref
id: C01571
db: KEGG Compound

Reference/KEGG Compound C00004
type: UnificationXref
id: C00004
db: KEGG Compound

Reference/ChEBI CHEBI 18367
type: UnificationXref
id: CHEBI:18367
db: ChEBI

Reference/KEGG Compound C00003
type: UnificationXref
id: C00003
db: KEGG Compound

Reference/ChemSpider 1032
type: UnificationXref
id: 1032
db: ChemSpider

Glycerol 3-phosphate
type: SmallMoleculeReference
xref: Reference/BioCyc GLYCEROL-3P
xref: Reference/HMDB HMDB0000126
xref: Reference/ChemSpider 388308
xref: Reference/CAS 17989-41-2
xref: Reference/KEGG Compound C00093
xref: Reference/ChEBI CHEBI 15978
xref: Reference/PubChem-compound 439162
chemical formula: C3H9O6P
molecular weight: 172.01367
structure: ChemicalStructure/PW C000081

ReactionCatalysis170895
type: Catalysis
controller: Glycerol-3-phosphate acyltransferase
controlled: Reaction180886
control type: ACTIVATION

Reference/CAS 57-04-5
type: UnificationXref
id: 57-04-5
db: CAS

Glycerol 3-phosphate
type: SmallMolecule
entity reference: Glycerol 3-phosphate

NAD
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 15846
xref: Reference/HMDB HMDB0000902
xref: Reference/CAS 53-84-9
xref: Reference/KEGG Compound C00003
xref: Reference/PubChem-compound 5893
xref: Reference/BioCyc NAD
xref: Reference/ChemSpider 5682
chemical formula: C21H27N7O14P2
molecular weight: 663.10913
structure: ChemicalStructure/PW C000721

Reference/ChEBI CHEBI 17361
type: UnificationXref
id: CHEBI:17361
db: ChEBI

ReactionCatalysis170896
type: Catalysis
controller: 1-acyl-sn-glycerol-3-phosphate acyltransferase
controlled: Reaction180887
control type: ACTIVATION

Reference/KEGG Compound C00010
type: UnificationXref
id: C00010
db: KEGG Compound

Reference/HMDB HMDB0000902
type: UnificationXref
id: HMDB0000902
db: HMDB

Putative cardiolipin synthase ybhO
type: ProteinReference
xref: Reference/UniProt P0AA84

Reference/KEGG Compound C00013
type: UnificationXref
id: C00013
db: KEGG Compound

Reference/BioCyc L-PHOSPHATIDATE
type: UnificationXref
id: L-PHOSPHATIDATE
db: BioCyc

Pyrophosphate
type: SmallMoleculeReference
xref: Reference/PubChem-compound 644102
xref: Reference/BioCyc PPI
xref: Reference/ChemSpider 559142
xref: Reference/ChEBI CHEBI 18361
xref: Reference/HMDB HMDB0000250
xref: Reference/CAS 14000-31-8
xref: Reference/KEGG Compound C00013
chemical formula: H4O7P2
molecular weight: 177.94322
structure: ChemicalStructure/PW C000170

NADH
type: SmallMoleculeReference
xref: Reference/HMDB HMDB0001487
xref: Reference/CAS 58-68-4
xref: Reference/PubChem-compound 439153
xref: Reference/BioCyc NADH
xref: Reference/ChemSpider 388299
xref: Reference/KEGG Compound C00004
xref: Reference/ChEBI CHEBI 16908
chemical formula: C21H29N7O14P2
molecular weight: 665.12476
structure: ChemicalStructure/PW C001144

PA(12:0/12:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00416
xref: Reference/BioCyc L-PHOSPHATIDATE
xref: Reference/ChEBI CHEBI 16337
chemical formula: C27H53O8P
molecular weight: 536.3478
structure: ChemicalStructure/PW C055517

Reference/ChEBI CHEBI 15978
type: UnificationXref
id: CHEBI:15978
db: ChEBI

Cytidine triphosphate
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17677
xref: Reference/CAS 65-47-4
xref: Reference/PubChem-compound 6176
xref: Reference/KEGG Compound C00063
xref: Reference/ChemSpider 5941
xref: Reference/HMDB HMDB0000082
xref: Reference/BioCyc CTP
chemical formula: C9H16N3O14P3
molecular weight: 482.9845
structure: ChemicalStructure/PW C000057

LysoPC(12:0/0:0)
type: SmallMolecule
entity reference: LysoPC(12:0/0:0)

PA(12:0/12:0)
type: SmallMolecule
entity reference: PA(12:0/12:0)

Reference/TAXONOMY 562
type: UnificationXref
id: 562
db: TAXONOMY

Reference/CAS 334-48-5
type: UnificationXref
id: 334-48-5
db: CAS

Hydrogen Ion
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00080
xref: Reference/ChEBI CHEBI 15378
xref: Reference/HMDB HMDB0059597
xref: Reference/PubChem-compound 1038
xref: Reference/ChemSpider 1010
chemical formula: H
molecular weight: 1.007825
structure: ChemicalStructure/PW C040034

Reference/UniProt P0A6H8
type: UnificationXref
id: P0A6H8
db: UniProt

Reference/ChemSpider 388308
type: UnificationXref
id: 388308
db: ChemSpider

Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL
type: UnificationXref
id: L-1-PHOSPHATIDYL-GLYCEROL
db: BioCyc

Reference/CAS 53-84-9
type: UnificationXref
id: 53-84-9
db: CAS

Reference/KEGG Compound C00269
type: UnificationXref
id: C00269
db: KEGG Compound

Reference/KEGG Compound C03892
type: UnificationXref
id: C03892
db: KEGG Compound

Glycerol-3-phosphate dehydrogenase
type: Complex
component: Glycerol-3-phosphate dehydrogenase [NAD(P)+]

Cytidine monophosphate
type: SmallMolecule
entity reference: Cytidine monophosphate

Glycerol-3-phosphate acyltransferase
type: ProteinReference
xref: Reference/UniProt P0A7A7

Reference/HMDB HMDB0000126
type: UnificationXref
id: HMDB0000126
db: HMDB

Compound/PW C042968/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPA(12:0/0:0)
stoichiometric coefficient: 1.0

Cytidine monophosphate
type: SmallMoleculeReference
xref: Reference/BioCyc CMP
xref: Reference/ChemSpider 5901
xref: Reference/PubChem-compound 6131
xref: Reference/ChEBI CHEBI 17361
xref: Reference/KEGG Compound C00055
xref: Reference/HMDB HMDB0000095
xref: Reference/CAS 63-37-6
chemical formula: C9H14N3O8P
molecular weight: 323.05185
structure: ChemicalStructure/PW C000064

PGP(10:0/10:0)
type: SmallMolecule
entity reference: PGP(10:0/10:0)

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: ProteinReference

Compound/PW C000721/Stoichiometry/1.0
type: Stoichiometry
physical entity: NAD
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000721
type: ChemicalStructure
structure format: SMILES

Reference/BioCyc CPD-8587
type: UnificationXref
id: CPD-8587
db: BioCyc

Reference/KEGG Compound C00157
type: UnificationXref
id: C00157
db: KEGG Compound

Reference/ChemSpider 5682
type: UnificationXref
id: 5682
db: ChemSpider

ChemicalStructure/PW C001144
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 1146900
type: UnificationXref
id: CHEBI:1146900
db: ChEBI

Water
type: SmallMolecule
entity reference: Water

ChemicalStructure/PW C000057
type: ChemicalStructure
structure format: SMILES

Phosphatidate cytidylyltransferase
type: ProteinReference

LysoPC(12:0/0:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C04230
xref: Reference/BioCyc PHOSPHATIDYLCHOLINE
chemical formula: C20H42NO7P
molecular weight: 439.2699
structure: ChemicalStructure/PW C108328

Reference/HMDB HMDB0000250
type: UnificationXref
id: HMDB0000250
db: HMDB

Phosphatidylglycerophosphatase B
type: Protein
entity reference: Phosphatidylglycerophosphatase B

ChemicalStructure/PW C000170
type: ChemicalStructure
structure format: SMILES
structure data: OP(O)(=O)OP(O)(O)=O

Reference/CAS 14000-31-8
type: UnificationXref
id: 14000-31-8
db: CAS

ChemicalStructure/PW C041600
type: ChemicalStructure
structure format: SMILES

Reference/ChEBI CHEBI 17517
type: UnificationXref
id: CHEBI:17517
db: ChEBI

Reference/BioCyc CO-A
type: UnificationXref
id: CO-A
db: BioCyc

Reference/ChemSpider 648
type: UnificationXref
id: 648
db: ChemSpider

Reaction2143786
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043864/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041600/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001104/Stoichiometry/1.0
right: PG(12:0/12:0)
right: Phosphate
spontaneous: false
left: PGP(10:0/10:0)
left: Water
name: PGP(10:0/10:0) + Water → PG(12:0/12:0) + Phosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C041600/Stoichiometry/1.0
type: Stoichiometry
physical entity: PG(12:0/12:0)
stoichiometric coefficient: 1.0

Coenzyme A
type: SmallMolecule
entity reference: Coenzyme A

2.7.8.5
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C044232/Stoichiometry/1.0
participant stoichiometry: Compound/PW C043864/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: PGP(10:0/10:0)
right: Hydrogen Ion
spontaneous: false
EC number: 2.7.8.5
left: CDP-DG(12:0/12:0)
left: Glycerol 3-phosphate
name: CDP-DG(12:0/12:0) + Glycerol 3-phosphate → Cytidine monophosphate + Hydrogen Ion + PGP(10:0/10:0)
conversion direction: LEFT_TO_RIGHT

ChemicalStructure/PW C000064
type: ChemicalStructure
structure format: SMILES

Coenzyme A
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 1146900
xref: Reference/HMDB HMDB0001423
xref: Reference/PubChem-compound 6816
xref: Reference/BioCyc CO-A
xref: Reference/ChemSpider 6557
xref: Reference/CAS 85-61-0
xref: Reference/KEGG Compound C00010
chemical formula: C21H36N7O16P3S
molecular weight: 767.11523
structure: ChemicalStructure/PW C001099

2.7.7.41
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000170/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000057/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055517/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
participant stoichiometry: Compound/PW C044232/Stoichiometry/1.0
right: CDP-DG(12:0/12:0)
right: Pyrophosphate
spontaneous: false
EC number: 2.7.7.41
left: Cytidine triphosphate
left: Hydrogen Ion
left: PA(12:0/12:0)
name: Cytidine triphosphate + Hydrogen Ion + PA(12:0/12:0) → CDP-DG(12:0/12:0) + Pyrophosphate
conversion direction: LEFT_TO_RIGHT

Compound/PW C000170/Stoichiometry/1.0
type: Stoichiometry
physical entity: Pyrophosphate
stoichiometric coefficient: 1.0

Glycerol-3-phosphate dehydrogenase [NAD(P)+]
type: ProteinReference

Reference/HMDB HMDB0001473
type: UnificationXref
id: HMDB0001473
db: HMDB

Reference/ChemSpider 5901
type: UnificationXref
id: 5901
db: ChemSpider

Reference/ChEBI CHEBI 17962
type: UnificationXref
id: CHEBI:17962
db: ChEBI

Reference/ChemSpider 6557
type: UnificationXref
id: 6557
db: ChemSpider

Reference/SMPDB SMP0724560
type: UnificationXref
id: SMP0724560
db: SMPDB

Reference/PubChem-compound 668
type: UnificationXref
id: 668
db: PubChem-compound

Reference/KEGG Compound C00055
type: UnificationXref
id: C00055
db: KEGG Compound

Escherichia coli
type: BioSource
xref: Reference/TAXONOMY 562

Reference/ChemSpider 388299
type: UnificationXref
id: 388299
db: ChemSpider

Reference/CAS 7732-18-5
type: UnificationXref
id: 7732-18-5
db: CAS

CL(12:0/12:0/28:1(11Z)/28:1(11Z))
type: SmallMoleculeReference
chemical formula: C89H170O17P2
molecular weight: 1573.1913

Reference/HMDB HMDB0001487
type: UnificationXref
id: HMDB0001487
db: HMDB

3.5.1.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000391/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001420/Stoichiometry/1.0
participant stoichiometry: Compound/PW C284616/Stoichiometry/1.0
participant stoichiometry: Compound/PW C105377/Stoichiometry/1.0
right: Capric acid
right: MLCL(0:0/12:0/12:0/28:1(11Z))
spontaneous: false
EC number: 3.5.1.-
left: Water
left: CL(12:0/12:0/28:1(11Z)/28:1(11Z))
name: CL(12:0/12:0/28:1(11Z)/28:1(11Z)) + Water → Capric acid + MLCL(0:0/12:0/12:0/28:1(11Z))
conversion direction: LEFT_TO_RIGHT

2.7.8.-
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000064/Stoichiometry/1.0
participant stoichiometry: Compound/PW C284424/Stoichiometry/1.0
participant stoichiometry: Compound/PW C284616/Stoichiometry/1.0
participant stoichiometry: Compound/PW C041600/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: Cytidine monophosphate
right: Hydrogen Ion
right: CL(12:0/12:0/28:1(11Z)/28:1(11Z))
spontaneous: false
EC number: 2.7.8.-
left: PG(12:0/12:0)
left: CDP-DG(28:1(11Z)/28:1(11Z))
name: CDP-DG(28:1(11Z)/28:1(11Z)) + PG(12:0/12:0) → CL(12:0/12:0/28:1(11Z)/28:1(11Z)) + Cytidine monophosphate + Hydrogen Ion
conversion direction: LEFT_TO_RIGHT

Compound/PW C001134/Stoichiometry/1.0
type: Stoichiometry
physical entity: Dihydroxyacetone phosphate
stoichiometric coefficient: 1.0

2.3.1.23
type: BiochemicalReaction
participant stoichiometry: Compound/PW C055670/Stoichiometry/1.0
participant stoichiometry: Compound/PW C108328/Stoichiometry/1.0
participant stoichiometry: Compound/PW C284616/Stoichiometry/1.0
participant stoichiometry: Compound/PW C105377/Stoichiometry/1.0
right: LysoPC(12:0/0:0)
right: CL(12:0/12:0/28:1(11Z)/28:1(11Z))
spontaneous: false
EC number: 2.3.1.23
left: MLCL(0:0/12:0/12:0/28:1(11Z))
left: PC(12:0/12:0)
name: MLCL(0:0/12:0/12:0/28:1(11Z)) + PC(12:0/12:0) → CL(12:0/12:0/28:1(11Z)/28:1(11Z)) + LysoPC(12:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/KEGG Compound C00063
type: UnificationXref
id: C00063
db: KEGG Compound

Reference/ChEBI CHEBI 30813
type: UnificationXref
id: CHEBI:30813
db: ChEBI

Reference/BioCyc CDPDIACYLGLYCEROL
type: UnificationXref
id: CDPDIACYLGLYCEROL
db: BioCyc

Reference/UniProt P0AA84
type: UnificationXref
id: P0AA84
db: UniProt

ChemicalStructure/PW C105377
type: ChemicalStructure
structure format: SMILES

Compound/PW C284424/Stoichiometry/1.0
type: Stoichiometry
physical entity: CDP-DG(28:1(11Z)/28:1(11Z))
stoichiometric coefficient: 1.0

ChemicalStructure/PW C000391
type: ChemicalStructure
structure format: SMILES
structure data: CCCCCCCCCC(O)=O

ChemicalStructure/PW C001928
type: ChemicalStructure
structure format: SMILES

PGP(10:0/10:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 37393
xref: Reference/BioCyc L-1-PHOSPHATIDYL-GLYCEROL-P
xref: Reference/KEGG Compound C03892
chemical formula: C26H52O13P2
molecular weight: 634.2883
structure: ChemicalStructure/PW C043864

Reference/KEGG Compound C01832
type: UnificationXref
id: C01832
db: KEGG Compound

Reference/BioCyc DIHYDROXY-ACETONE-PHOSPHATE
type: UnificationXref
id: DIHYDROXY-ACETONE-PHOSPHATE
db: BioCyc

Compound/PW C001099/Stoichiometry/1.0
type: Stoichiometry
physical entity: Coenzyme A
stoichiometric coefficient: 1.0

Reference/ChemSpider 2863
type: UnificationXref
id: 2863
db: ChemSpider

MLCL(0:0/12:0/12:0/28:1(11Z))
type: SmallMoleculeReference
chemical formula: C61H118O16P2
molecular weight: 1168.7896
structure: ChemicalStructure/PW C105377

Compound/PW C001144/Stoichiometry/1.0
type: Stoichiometry
physical entity: NADH
stoichiometric coefficient: 1.0

Reference/PubChem-compound 165436
type: UnificationXref
id: 165436
db: PubChem-compound

CL(12:0/12:0/28:1(11Z)/28:1(11Z))
type: SmallMolecule
entity reference: CL(12:0/12:0/28:1(11Z)/28:1(11Z))

Reference/CAS 65-47-4
type: UnificationXref
id: 65-47-4
db: CAS

ChemicalStructure/PW C001134
type: ChemicalStructure
structure format: SMILES
structure data: OCC(=O)COP(O)(O)=O

Compound/PW C105377/Stoichiometry/1.0
type: Stoichiometry
physical entity: MLCL(0:0/12:0/12:0/28:1(11Z))
stoichiometric coefficient: 1.0

Reference/PubChem-compound 962
type: UnificationXref
id: 962
db: PubChem-compound

CDP-DG(28:1(11Z)/28:1(11Z))
type: SmallMolecule
entity reference: CDP-DG(28:1(11Z)/28:1(11Z))

Compound/PW C055670/Stoichiometry/1.0
type: Stoichiometry
physical entity: PC(12:0/12:0)
stoichiometric coefficient: 1.0

Reference/ChEBI CHEBI 16337
type: UnificationXref
id: CHEBI:16337
db: ChEBI

Reference/ChEBI CHEBI 37393
type: UnificationXref
id: CHEBI:37393
db: ChEBI

Reference/ChemSpider 145018
type: UnificationXref
id: 145018
db: ChemSpider

Phosphate
type: SmallMolecule
entity reference: Phosphate

Reference/PubChem-compound 5893
type: UnificationXref
id: 5893
db: PubChem-compound

Compound/PW C001104/Stoichiometry/1.0
type: Stoichiometry
physical entity: Phosphate
stoichiometric coefficient: 1.0

Compound/PW C001928/Stoichiometry/1.0
type: Stoichiometry
physical entity: Lauroyl-CoA
stoichiometric coefficient: 1.0

Reference/BioCyc CMP
type: UnificationXref
id: CMP
db: BioCyc

Compound/PW C000391/Stoichiometry/1.0
type: Stoichiometry
physical entity: Capric acid
stoichiometric coefficient: 1.0

Reference/KEGG Compound C00080
type: UnificationXref
id: C00080
db: KEGG Compound

Phosphatidylglycerophosphatase B
type: ProteinReference
xref: Reference/UniProt P0A924

1-acyl-sn-glycerol-3-phosphate acyltransferase
type: Protein
entity reference: 1-acyl-sn-glycerol-3-phosphate acyltransferase

ChemicalStructure/PW C055517
type: ChemicalStructure
structure format: SMILES

Reference/UniProt P0A924
type: UnificationXref
id: P0A924
db: UniProt

CDP-DG(12:0/12:0)
type: SmallMolecule
entity reference: CDP-DG(12:0/12:0)

Reference/HMDB HMDB0002111
type: UnificationXref
id: HMDB0002111
db: HMDB

Reaction180887
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042968/Stoichiometry/1.0
participant stoichiometry: Compound/PW C055517/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928/Stoichiometry/1.0
right: Coenzyme A
right: PA(12:0/12:0)
spontaneous: false
left: Lauroyl-CoA
left: LysoPA(12:0/0:0)
name: Lauroyl-CoA + LysoPA(12:0/0:0) → Coenzyme A + PA(12:0/12:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 17677
type: UnificationXref
id: CHEBI:17677
db: ChEBI

Reference/ChEBI CHEBI 15377
type: UnificationXref
id: CHEBI:15377
db: ChEBI

Reaction180886
type: BiochemicalReaction
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001099/Stoichiometry/1.0
participant stoichiometry: Compound/PW C042968/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001928/Stoichiometry/1.0
right: Coenzyme A
right: LysoPA(12:0/0:0)
spontaneous: false
left: Lauroyl-CoA
left: Glycerol 3-phosphate
name: Glycerol 3-phosphate + Lauroyl-CoA → Coenzyme A + LysoPA(12:0/0:0)
conversion direction: LEFT_TO_RIGHT

Reference/ChEBI CHEBI 15378
type: UnificationXref
id: CHEBI:15378
db: ChEBI

ChemicalStructure/PW C040034
type: ChemicalStructure
structure format: SMILES
structure data: [H+]

Reference/PubChem-compound 6176
type: UnificationXref
id: 6176
db: PubChem-compound

Reference/CAS 14265-44-2
type: UnificationXref
id: 14265-44-2
db: CAS

Reference/ChEBI CHEBI 16108
type: UnificationXref
id: CHEBI:16108
db: ChEBI

Reference/CAS 17989-41-2
type: UnificationXref
id: 17989-41-2
db: CAS

Compound/PW C108328/Stoichiometry/1.0
type: Stoichiometry
physical entity: LysoPC(12:0/0:0)
stoichiometric coefficient: 1.0

Compound/PW C284616/Stoichiometry/1.0
type: Stoichiometry
physical entity: CL(12:0/12:0/28:1(11Z)/28:1(11Z))
stoichiometric coefficient: 1.0

LysoPA(12:0/0:0)
type: SmallMolecule
entity reference: LysoPA(12:0/0:0)

Compound/PW C001420/Stoichiometry/1.0
type: Stoichiometry
physical entity: Water
stoichiometric coefficient: 1.0

Reference/BioCyc GLYCEROL-3P
type: UnificationXref
id: GLYCEROL-3P
db: BioCyc

phosphatidylglycerophosphatase
type: Complex
component: Phosphatidylglycerophosphatase B
component: Phosphatidylglycerophosphatase A

Reference/KEGG Compound C00093
type: UnificationXref
id: C00093
db: KEGG Compound

Reference/HMDB HMDB0003571
type: UnificationXref
id: HMDB0003571
db: HMDB

Reference/PathWhiz PW762339
type: UnificationXref
id: PW762339
db: PathWhiz

Reference/KEGG Compound C00416
type: UnificationXref
id: C00416
db: KEGG Compound

Reference/PubChem-compound 644102
type: UnificationXref
id: 644102
db: PubChem-compound

Reference/ChemSpider 5941
type: UnificationXref
id: 5941
db: ChemSpider

LysoPA(12:0/0:0)
type: SmallMoleculeReference
xref: Reference/KEGG Compound C00681
xref: Reference/BioCyc ACYL-SN-GLYCEROL-3P
xref: Reference/ChEBI CHEBI 62840
chemical formula: C15H31O7P
molecular weight: 354.18073
structure: ChemicalStructure/PW C042968

Reference/UniProt P0A7A7
type: UnificationXref
id: P0A7A7
db: UniProt

Compound/PW C055517/Stoichiometry/1.0
type: Stoichiometry
physical entity: PA(12:0/12:0)
stoichiometric coefficient: 1.0

Reference/CAS 6244-92-4
type: UnificationXref
id: 6244-92-4
db: CAS

Cardiolipin synthase
type: Protein
entity reference: Cardiolipin synthase

Reaction2143079
type: BiochemicalReaction
participant stoichiometry: Compound/PW C001134/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000721/Stoichiometry/1.0
participant stoichiometry: Compound/PW C000081/Stoichiometry/1.0
participant stoichiometry: Compound/PW C001144/Stoichiometry/1.0
participant stoichiometry: Compound/PW C040034/Stoichiometry/1.0
right: NAD
right: Glycerol 3-phosphate
spontaneous: false
left: NADH
left: Dihydroxyacetone phosphate
left: Hydrogen Ion
name: Dihydroxyacetone phosphate + Hydrogen Ion + NADH ↔ Glycerol 3-phosphate + NAD
conversion direction: REVERSIBLE

Reference/PubChem-compound 2969
type: UnificationXref
id: 2969
db: PubChem-compound

Water
type: SmallMoleculeReference
xref: Reference/PubChem-compound 962
xref: Reference/ChEBI CHEBI 15377
xref: Reference/KEGG Compound C00001
xref: Reference/ChemSpider 937
xref: Reference/HMDB HMDB0002111
xref: Reference/CAS 7732-18-5
chemical formula: H2O
molecular weight: 18.010565
structure: ChemicalStructure/PW C001420

Reference/HMDB HMDB0000511
type: UnificationXref
id: HMDB0000511
db: HMDB

ChemicalStructure/PW C108328
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](O)(COC(=O)CCCCCCCCCCC)COP([O-])(=O)OCC[N+](C)(C)C

Reference/BioCyc NADH
type: UnificationXref
id: NADH
db: BioCyc

Reference/BioCyc NAD
type: UnificationXref
id: NAD
db: BioCyc

CDP-DG(12:0/12:0)
type: SmallMoleculeReference
xref: Reference/ChEBI CHEBI 17962
xref: Reference/BioCyc CDPDIACYLGLYCEROL
xref: Reference/KEGG Compound C00269
chemical formula: C36H65N3O15P2
molecular weight: 841.3891
structure: ChemicalStructure/PW C044232

Reference/PubChem-compound 1061
type: UnificationXref
id: 1061
db: PubChem-compound

Phosphatidylserine synthase
type: ProteinReference

Probable HTH-type transcriptional regulator LrhA
type: ProteinReference

Reference/HMDB HMDB0059597
type: UnificationXref
id: HMDB0059597
db: HMDB

Compound/PW C000081/Stoichiometry/1.0
type: Stoichiometry
physical entity: Glycerol 3-phosphate
stoichiometric coefficient: 1.0

ChemicalStructure/PW C055670
type: ChemicalStructure
structure format: SMILES
structure data: [H][C@@](COC(=O)CCCCCCCCCCC)(COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCC

Reference/BioCyc PHOSPHATIDYLCHOLINE
type: UnificationXref
id: PHOSPHATIDYLCHOLINE
db: BioCyc

Reference/KEGG Compound C04230
type: UnificationXref
id: C04230
db: KEGG Compound

cardiolipin synthase
type: Complex
component: Putative cardiolipin synthase ybhO
component: Cardiolipin synthase

Reference/HMDB HMDB0000082
type: UnificationXref
id: HMDB0000082
db: HMDB

Reference/CAS 85-61-0
type: UnificationXref
id: 85-61-0
db: CAS

Alpha/beta hydrolase
type: ProteinReference

ChemicalStructure/PW C000081
type: ChemicalStructure
structure format: SMILES
structure data: OC[C@@H](O)COP(O)(O)=O

M48 family metalloprotease
type: ProteinReference