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PathWhiz ID Pathway Meta Data

PW132191

Pw132191 View Pathway
metabolic

Aluminum zirconium octachlorohydrex gly Drug Metabolism

Homo sapiens
Aluminum zirconium octachlorohydrex gly is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Aluminum zirconium octachlorohydrex gly passes through the liver and is then excreted from the body mainly through the kidney.

PW146293

Pw146293 View Pathway
drug action

Aluminum zirconium octachlorohydrex gly Drug Metabolism Action Pathway

Homo sapiens

PW146264

Pw146264 View Pathway
drug action

Aluminum zirconium pentachlorohydrate Drug Metabolism Action Pathway

Homo sapiens

PW146336

Pw146336 View Pathway
drug action

Aluminum zirconium pentachlorohydrex gly Drug Metabolism Action Pathway

Homo sapiens

PW146266

Pw146266 View Pathway
drug action

Aluminum zirconium tetrachlorohydrex gly Drug Metabolism Action Pathway

Homo sapiens

PW146240

Pw146240 View Pathway
drug action

Aluminum zirconium trichlorohydrex gly Drug Metabolism Action Pathway

Homo sapiens

PW145481

Pw145481 View Pathway
drug action

Alverine Drug Metabolism Action Pathway

Homo sapiens

PW128331

Pw128331 View Pathway
drug action

Alverine Serotonin Antagonist Action Pathway

Homo sapiens
Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is also useful in treating irritable bowel syndrome (IBS) and similar conditions. Alverine also relaxes the smooth muscle in the womb (uterus). It is therefore also used to treat painful menstruation, which is caused by muscle spasms in the uterus (dysmenorrhea). Alverine citrate is also under investigation to increase the cytotoxic effects of the proteasome inhibitor MG132 on breast cancer cells.

PW000662

Pw000662 View Pathway
drug action

Alvimopan Action Pathway

Homo sapiens
Alvimopan is prescribed to treat patient opioid-induced constipation, a common side effect of opioid therapy. This side effect results in delayed discharge for hospitalized patients following surgery. Alvimopan helps to increase gastrointestinal recovery following surgery for a shorter hospital stay. Opioids bind opioid receptors in the gut causing inhibition of gut motility which results in constipation. Alvimopan is a peripherally acting mu-opioid antagonist. The drug acts in the gastrointestinal tract by competing to bind the mu-opioid receptor. Alvimopan differs from other peripherally acting mu-receptor antagonists such as, methylnaltrexone, by the presence of a quaternary amine.

PW145698

Pw145698 View Pathway
drug action

Alvimopan Drug Metabolism Action Pathway

Homo sapiens