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Pathways

PathWhiz ID Pathway Meta Data

PW132175

Pw132175 View Pathway
metabolic

Propylene glycol Drug Metabolism

Homo sapiens
Propylene glycol is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Propylene glycol passes through the liver and is then excreted from the body mainly through the kidney.

PW145501

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drug action

Propylene glycol Drug Metabolism Action Pathway

Homo sapiens

PW132555

Pw132555 View Pathway
metabolic

Propylhexedrine Drug Metabolism

Homo sapiens
Propylhexedrine is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Propylhexedrine passes through the liver and is then excreted from the body mainly through the kidney.

PW145755

Pw145755 View Pathway
drug action

Propylhexedrine Drug Metabolism Action Pathway

Homo sapiens

PW146114

Pw146114 View Pathway
drug action

Propyliodone Drug Metabolism Action Pathway

Homo sapiens

PW146774

Pw146774 View Pathway
drug action

Propylparaben Drug Metabolism Action Pathway

Homo sapiens

PW132342

Pw132342 View Pathway
metabolic

Propylthiouracil Drug Metabolism

Homo sapiens
Propylthiouracil is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Propylthiouracil passes through the liver and is then excreted from the body mainly through the kidney.

PW144667

Pw144667 View Pathway
drug action

Propylthiouracil Drug Metabolism Action Pathway

Homo sapiens

PW128489

Pw128489 View Pathway
drug action

Protein C Action Pathway

Homo sapiens
Protein C is also known under brand names such as Balfaxar, Beriplex, Ceprotin, Kcentra and Octaplex used to treat purpura fulminans and or coumarin-induced skin necrosis. Protein C is an endogenous plasma protein, a zymogen that interacts with thrombomodulin in order to be converted to its active form. Activated Protein C acts as a serine protease that acts by inactivating coagulation factors V and VIII, decreasing clot formation. Due to its anticoagulant nature herbs and supplements with similar activity should be avoided such as garlic, ginger, bilberry, danshen, piracetam, and ginkgo biloba.

PW120685

Pw120685 View Pathway
protein

Protein Synthesis: Alanine

Rattus norvegicus
Protein synthesis is an essential life process that builds the important large amino acid macromolecules that function as enzymes, antibodies, and cellular structural components. Although synthesis begins with the transcription of DNA into RNA, this pathway depicts the reactions that occur during translation. Transcribed messenger RNA (mRNA), which contains the genetic code to direct protein synthesis, is transported out of the nucleus and becomes bound to ribosomes in the cytoplasm or endoplasmic reticulum. The amino acids required to assemble polypeptide chains are delivered to the ribosomes using transfer RNA (tRNA). Each tRNA molecule has both a binding site for a specific amino acid and a three-nucleotide sequence called the anticodon that forms three complementary base pairs with an mRNA codon. Charging or loading the appropriate amino acid onto its tRNA is carried out by an aminoacyl-tRNA synthetase (aaRS or ARS), also called tRNA-ligase. This enzyme catalyzes the esterification of an amino acid to one of all its compatible tRNAs to form an aminoacyl-tRNA. Each of the twenty amino acids has a corresponding aa-tRNA made by a specific aminoacyl-tRNA synthetase. Ribosomes match the anticodons of the charged tRNA molecules with successive codons of the mRNA. After a match is found, the ribosome transfers the amino acid from the matching tRNA onto the growing peptide chain via a reaction termed peptide condensation, and the tRNAs, no longer carrying amino acids, are released.