PathWhiz ID | Pathway | Meta Data |
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PW012863View Pathway |
signaling
A20 mechanism pathwayHomo sapiens
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Creator: Guest: Anonymous Created On: November 16, 2016 at 00:18 Last Updated: November 16, 2016 at 00:18 |
PW128481View Pathway |
drug action
a Action PathwayHomo sapiens
Human thrombin is a platelet-activating factor also known under the brand names Artiss, Evarrest, Evicel, Evithrom, Tachosil, Tisseel and Vistaseal. Human thrombin is purified human thrombin, a highly specific serine protease that acts on fibrinogen to fibrin, leading to the formation of a blood clot. It also acts on coagulation factor XIII to activate it and establish cross-linking of fibrin producing a clot. It is used as a topical application to a surgical site to minimize bleeding. Human thrombin is metabolized the same way as endogenous thrombin, inactivated by plasma inhibitors.
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Creator: Selena Created On: August 30, 2023 at 20:25 Last Updated: August 30, 2023 at 20:25 |
PW122161View Pathway |
physiological
aAndrographolide
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Creator: Guest: Anonymous Created On: September 19, 2018 at 07:07 Last Updated: September 19, 2018 at 07:07 |
PW064708View Pathway |
disease
aBacteria
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Creator: Guest: Anonymous Created On: March 29, 2018 at 01:51 Last Updated: March 29, 2018 at 01:51 |
PW124259View Pathway |
protein
aHomo sapiens
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Creator: Guest: Anonymous Created On: October 20, 2020 at 23:11 Last Updated: October 20, 2020 at 23:11 |
PW146992View Pathway |
9-cis-Retinoic acid Drug Metabolism PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 10, 2023 at 13:36 Last Updated: October 10, 2023 at 13:36 |
PW121923View Pathway |
disease
5-OxoprolinuriaRattus norvegicus
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.
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Creator: Ana Marcu Created On: September 10, 2018 at 15:51 Last Updated: September 10, 2018 at 15:51 |
PW000074View Pathway |
disease
5-OxoprolinuriaHomo sapiens
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.
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Creator: WishartLab Created On: August 01, 2013 at 15:52 Last Updated: August 01, 2013 at 15:52 |
PW127179View Pathway |
disease
5-OxoprolinuriaHomo sapiens
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.
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Creator: Ray Kruger Created On: November 02, 2022 at 15:31 Last Updated: November 02, 2022 at 15:31 |
PW121697View Pathway |
disease
5-OxoprolinuriaMus musculus
5-Oxoprolinuria (5-Oxoprolinase deficiency) is a result of a defect in the gamma-glutamyl cycle due to either 5-oxoprolinase or glutathione synthetase deficiency. In the case of glutathione synthetase deficiency, the glycine is not incorporated into gamma-glutamylcysteine. In the case of 5-oxoprolinase, however, pyroglutamic acid accumulates. Symptoms include anemia, mental retardation, metabolic acidosis, respiratory distress and urolithiasis.
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Creator: Ana Marcu Created On: September 10, 2018 at 15:49 Last Updated: September 10, 2018 at 15:49 |