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Pathways

PathWhiz ID Pathway Meta Data

PW124321

Pw124321 View Pathway
metabolic

Biosíntesis de Colesterol (CV)

Homo sapiens
Biosíntesis de colesterol a partir de Acetil-CoA.

PW124314

Pw124314 View Pathway
metabolic

Biosíntesis de colesterol (error)

Homo sapiens
Síntesis de colesterol a partir de Acetil-CoA.

PW124227

Pw124227 View Pathway
metabolic

biosíntesis de pirimidinas

Homo sapiens
Estas bases son de crucial importancia debido a que su secuenciación en el ADN y el ARN, es la forma en que se almacena la información. Las letras que forman los codones en el código genético son la A, C, U, y G de las bases.http://hyperphysics.phy-astr.gsu.edu/hbasees/Organic/base.html

PW124591

Pw124591 View Pathway
metabolic

Biosíntesis de Ácidos grasos

human

PW002380

Pw002380 View Pathway
metabolic

Biotin Biosynthesis

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Saccharomyces cerevisiae starts biotin biosynthesis from 8-amino-7-oxononanoate, which it can import from the environment by the transporter encoded by the BIO5 gene. Once 8-amino-7-oxononanoate reacts with the common methyl-group donor S-adenosyl-L-methionine as an amino-group donor, a reaction catalyzed by the BIO3-encoded 7,8-diamino-pelargonic acid aminotransferase resulting in the release of 7,8-diaminopelargonate, is the target of a unique carboxylase, the BIO4-encoded dethiobiotin synthetase. This enzymee catalyzes the first ring closure by a carboxylation reaction that does not require biotin as a prosthetic group, forming dethiobiotin. The last step in the pathway is catalyzed by biotin synthase, encoded by BIO2. This enzyme inserts a sulfur atom between C6 and C9 of dethiobiotin in a S-adenosyl-L-methionine-dependent reaction resulting in the release of biotin.

PW144267

Pw144267 View Pathway
drug action

Biotin Drug Metabolism Action Pathway

Homo sapiens

PW064578

Pw064578 View Pathway
metabolic

Biotin Metabolism

Mus musculus
Biotin is a vitamin that is an essential nutrient for humans. Biotin can be absorbed from consuming various foods such as: legumes, soybeans, tomatoes, romaine lettuce, eggs, cow's milk, oats and many more. Biotin acts as a cofactor for enzymes to catalyze carboxylation reactions involved in gluconeogenesis, amino acid catabolism and fatty acid metabolism. Biotin deficiency has been associated with many human diseases. These diseases may be caused by dysfunctional biotin metabolism due to enzyme deficiencies. Some research suggests biotin may play a role in transcription regulation or protein expression which may lead to biotin related diseases.

PW088202

Pw088202 View Pathway
metabolic

Biotin Metabolism

Bos taurus
Biotin is a vitamin that is an essential nutrient for humans. Biotin can be absorbed from consuming various foods such as: legumes, soybeans, tomatoes, romaine lettuce, eggs, cow's milk, oats and many more. Biotin acts as a cofactor for enzymes to catalyze carboxylation reactions involved in gluconeogenesis, amino acid catabolism and fatty acid metabolism. Biotin deficiency has been associated with many human diseases. These diseases may be caused by dysfunctional biotin metabolism due to enzyme deficiencies. Some research suggests biotin may play a role in transcription regulation or protein expression which may lead to biotin related diseases.

PW088396

Pw088396 View Pathway
metabolic

Biotin Metabolism

Drosophila melanogaster
Biotin is a vitamin that is an essential nutrient for humans. Biotin can be absorbed from consuming various foods such as: legumes, soybeans, tomatoes, romaine lettuce, eggs, cow's milk, oats and many more. Biotin acts as a cofactor for enzymes to catalyze carboxylation reactions involved in gluconeogenesis, amino acid catabolism and fatty acid metabolism. Biotin deficiency has been associated with many human diseases. These diseases may be caused by dysfunctional biotin metabolism due to enzyme deficiencies. Some research suggests biotin may play a role in transcription regulation or protein expression which may lead to biotin related diseases.

PW000013

Pw000013 View Pathway
metabolic

Biotin Metabolism

Homo sapiens
Biotin is a vitamin that is an essential nutrient for humans. Biotin can be absorbed from consuming various foods such as: legumes, soybeans, tomatoes, romaine lettuce, eggs, cow's milk, oats and many more. Biotin acts as a cofactor for enzymes to catalyze carboxylation reactions involved in gluconeogenesis, amino acid catabolism and fatty acid metabolism. Biotin deficiency has been associated with many human diseases. These diseases may be caused by dysfunctional biotin metabolism due to enzyme deficiencies. Some research suggests biotin may play a role in transcription regulation or protein expression which may lead to biotin related diseases.