PathWhiz

PathWhiz ID	Pathway	Meta Data
PW128386 View Pathway	drug action Dolasetron Serotonin antagonist Action Pathway Homo sapiens Dolasetron is a selective serotonin 5-HT3 receptor antagonist. In vivo, the drug is rapidly converted into its major active metabolite, hydrodolasetron, which seems to be largely responsible for the drug's pharmacological activity. The antiemetic activity of the drug is brought about through the inhibition of 5-HT3 receptors present both centrally (medullary chemoreceptor zone) and peripherally (GI tract). This inhibition of 5-HT3 receptors in turn inhibits the visceral afferent stimulation of the vomiting center, likely indirectly at the level of the area postrema, as well as through direct inhibition of serotonin activity within the area postrema and the chemoreceptor trigger zone. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: August 25, 2023 at 12:02 Last Updated: August 25, 2023 at 12:02
PW124234 View Pathway	metabolic chebulagic acid Metabolism 1602981862 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: October 17, 2020 at 18:44 Last Updated: October 17, 2020 at 18:44
PW124232 View Pathway	metabolic chebulagic acid Metabolism 1602980507 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: October 17, 2020 at 18:21 Last Updated: October 17, 2020 at 18:21
PW124219 View Pathway	physiological chebulagic acid Metabolism 1602639807 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: October 13, 2020 at 19:43 Last Updated: October 13, 2020 at 19:43
PW123825 View Pathway	signaling chebulagic acid Metabolism 1582757459 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: February 26, 2020 at 15:51 Last Updated: February 26, 2020 at 15:51
PW123807 View Pathway	signaling chebulagic acid Metabolism 1581839290 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: February 16, 2020 at 00:48 Last Updated: February 16, 2020 at 00:48
PW123794 View Pathway	signaling chebulagic acid Metabolism 1581167212 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: February 08, 2020 at 06:07 Last Updated: February 08, 2020 at 06:07
PW124042 View Pathway	signaling chebulagic acid Metabolism 1559277983 1596798296 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: August 07, 2020 at 05:05 Last Updated: August 07, 2020 at 05:05
PW124069 View Pathway	signaling chebulagic acid Metabolism 1559277983 1589861306 1597248631 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: August 12, 2020 at 10:10 Last Updated: August 12, 2020 at 10:10
PW123890 View Pathway	signaling chebulagic acid Metabolism 1559277983 1589861306 Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: May 18, 2020 at 22:06 Last Updated: May 18, 2020 at 22:06