PathWhiz ID | Pathway | Meta Data |
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PW146115View Pathway |
drug action
Polyestradiol phosphate Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:26 Last Updated: October 07, 2023 at 17:26 |
PW146276View Pathway |
drug action
Polyethylene glycol 300 Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:50 Last Updated: October 07, 2023 at 17:50 |
PW146218View Pathway |
drug action
Polyethylene glycol 400 Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:42 Last Updated: October 07, 2023 at 17:42 |
PW146071View Pathway |
drug action
Polyethylene glycol Drug Metabolism Action PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 07, 2023 at 17:20 Last Updated: October 07, 2023 at 17:20 |
PW125886View Pathway |
PolyhydroxyalkanoatesBacteria
This metabolic pathway contains the 3 important pathways
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Creator: Jonathan Created On: April 18, 2021 at 16:51 Last Updated: April 18, 2021 at 16:51 |
PW124456View Pathway |
polyhydroxyalkanoates synthesisBacteria
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Creator: Arun K B Created On: January 14, 2021 at 21:53 Last Updated: January 14, 2021 at 21:53 |
PW122263View Pathway |
Polyketide type II BiosynthesisBacteria
Polyketides are a large family of natural products found in bacteria, fungi and plants, and include many clinically important drugs such as tetracycline, daunorubicin, erythromycin,
rapamycin and lovastatin. They are biosynthesized from acyl CoA precursors by polyketide synthases (PKSs).
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Creator: Ng Ngashangva Created On: October 22, 2018 at 04:52 Last Updated: October 22, 2018 at 04:52 |
PW147044View Pathway |
Polymyxin B Sulfate Drug Metabolism PathwayHomo sapiens
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Creator: Ray Kruger Created On: October 10, 2023 at 13:43 Last Updated: October 10, 2023 at 13:43 |
PW002052View Pathway |
Polymyxin ResistanceEscherichia coli
UDP-glucuronic acid compound undergoes a NAD dependent reaction through a bifunctional polymyxin resistance protein to produce UDP-Beta-L-threo-pentapyranos-4-ulose. This compound then reacts with L-glutamic acid through a UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase to produce an oxoglutaric acid and UDP-4-amino-4-deoxy-beta-L-arabinopyranose The latter compound interacts with a N10-formyl-tetrahydrofolate through a bifunctional polymyxin resistance protein ArnA, resulting in a tetrahydrofolate, a hydrogen ion and a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose, which in turn reacts with a product of the methylerythritol phosphate and polysoprenoid biosynthesis pathway, di-trans,octa-cis-undecaprenyl phosphate to produce a 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate.
The compound 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate hypothetically reacts with water and results in the release of a formic acid and 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate which in turn reacts with a KDO2-lipid A through a 4-amino-4-deoxy-L-arabinose transferase resulting in the release of a di-trans,octa-cis-undecaprenyl phosphate and a L-Ara4N-modified KDO2-Lipid A
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Creator: miguel ramirez Created On: October 08, 2015 at 11:52 Last Updated: October 08, 2015 at 11:52 |
PW123542View Pathway |
Polymyxin ResistancePseudomonas aeruginosa
UDP-glucuronic acid compound undergoes a NAD dependent reaction through a bifunctional polymyxin resistance protein to produce UDP-Beta-L-threo-pentapyranos-4-ulose. This compound then reacts with L-glutamic acid through a UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase to produce an oxoglutaric acid and UDP-4-amino-4-deoxy-beta-L-arabinopyranose The latter compound interacts with a N10-formyl-tetrahydrofolate through a bifunctional polymyxin resistance protein ArnA, resulting in a tetrahydrofolate, a hydrogen ion and a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose, which in turn reacts with a product of the methylerythritol phosphate and polysoprenoid biosynthesis pathway, di-trans,octa-cis-undecaprenyl phosphate to produce a 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate.
The compound 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans, octacis-undecaprenyl phosphate hypothetically reacts with water and results in the release of a formic acid and 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate which in turn reacts with a KDO2-lipid A through a 4-amino-4-deoxy-L-arabinose transferase resulting in the release of a di-trans,octa-cis-undecaprenyl phosphate and a L-Ara4N-modified KDO2-Lipid A
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Creator: Ana Marcu Created On: August 12, 2019 at 22:29 Last Updated: August 12, 2019 at 22:29 |