PathWhiz

PathWhiz ID	Pathway	Meta Data
PW000038 View Pathway	metabolic Taurine and Hypotaurine Metabolism Homo sapiens There is an organic acid known as Taurine, which is a derivative product of sulfhydryl amino acid (which contains sulfur), as well as cysteine. The synthesis or metabolism in mammalian systems of this acid transpires within the pancreas in such a fashion that it utilizes a pathway known as the cysteine sulfinic acid pathway. To put this process in context, its occurrence is often seen in vivo, in hepatocytes, and is fundamental in the cyclical process of recovering bile acids from the intenstine, turning them back into salts and returning them to the bile. In essence the cysteine pathway induces a sulfhydryl group to be oxidized, creating cysteine sulfinic acid, by utilizing the appropriate enzymes (ie cysteine dioxygenase). This new acid undergoes decarboxylation creating a new compound: hypotaurine. This process goes on as Taurine now is subjected to conjugation vis a vis its amino terminal group. This includes acids such as chenodeoxycholic acid and cholic acid, and in turn the formation of bile salts occurs. Moreover, this entire process can be catalyzed via bile acid and a special amino acid N-acetyltransferase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 01, 2013 at 13:54 Last Updated: August 01, 2013 at 13:54
PW145503 View Pathway	drug action Taurine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:57 Last Updated: October 07, 2023 at 15:57
PW122576 View Pathway	metabolic Taurine Metabolism Pseudomonas aeruginosa Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 12, 2019 at 16:59 Last Updated: August 12, 2019 at 16:59
PW000774 View Pathway	metabolic Taurine Metabolism Escherichia coli Taurine enters into the cytoplasm through a taurine ATP-binding cassette (ABC) transporters. Once inside, the enzyme taurine dioxygenase encourages the interaction between taurine, oxoglutaric acid and oxygen resulting in the release of succinic acid, sulfite, aminoacetaldehyde, and carbon dioxide. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: February 09, 2015 at 00:52 Last Updated: February 09, 2015 at 00:52
PW001028 View Pathway	metabolic Taurine Metabolism I Escherichia coli Taurine is incorporated into the cytoplasm through a taurine ABC transporter. Once inside the cytoplasm, taurine interacts with an oxoglutaric acid and an oxygen through a taurine dioxygenase resulting in the release of succinic acid, sulfite , aminoacetaldehyde and carbon dioxide. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: August 20, 2015 at 17:25 Last Updated: August 20, 2015 at 17:25
PW122665 View Pathway	metabolic Taurine Metabolism I Pseudomonas aeruginosa Taurine is incorporated into the cytoplasm through a taurine ABC transporter. Once inside the cytoplasm, taurine interacts with an oxoglutaric acid and an oxygen through a taurine dioxygenase resulting in the release of succinic acid, sulfite , aminoacetaldehyde and carbon dioxide. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 12, 2019 at 18:40 Last Updated: August 12, 2019 at 18:40
PW145556 View Pathway	drug action Taurocholic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:04 Last Updated: October 07, 2023 at 16:04
PW146531 View Pathway	drug action Taurolidine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:26 Last Updated: October 07, 2023 at 18:26
PW176142 View Pathway	metabolic Taurolidine Predicted Metabolism Pathway new Homo sapiens Metabolites of Taurolidine are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 14:16 Last Updated: November 29, 2023 at 14:16
PW145851 View Pathway	drug action Tauroursodeoxycholic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:49 Last Updated: October 07, 2023 at 16:49