PathWhiz

PathWhiz ID	Pathway	Meta Data
PW146928 View Pathway	drug action Sotorasib Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 19:22 Last Updated: October 07, 2023 at 19:22
PW146753 View Pathway	drug action Soy isoflavones Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:57 Last Updated: October 07, 2023 at 18:57
PW130048 View Pathway	metabolic Soybean Drug Metabolism Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Selena Created On: September 14, 2023 at 20:32 Last Updated: September 14, 2023 at 20:32
PW145294 View Pathway	drug action Sparfloxacin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:29 Last Updated: October 07, 2023 at 15:29
PW000356 View Pathway	drug action Spectinomycin Action Pathway Homo sapiens Spectinomycin (also named Togamycin or Trobicin) is an aminocyclitol antibiotic for the treatment of gonorrhea infections such as penicillin-resistant Neisseria gonorrhoeae (experimental studies shows that spectinomycin equips with bacteriostatic effect against most Neisseria gonorrhoeae strains). It is produced from Streptomyces spectabilis, which is a soil microorganism. Spectinomycin reversibly interferes with the interaction between mRNA and the bacterial 30S ribosomal subunit. It is structurally similar to aminoglycosides, but does not cause misreading of mRNA. It is structurally similar to aminoglycosides, but does not cause misreading of mRNA. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 22, 2013 at 10:45 Last Updated: August 22, 2013 at 10:45
PW125964 View Pathway	drug action Spectinomycin Anti-bacterial Action Pathway Homo sapiens Spectinomycin is an aminocyclitol antibiotic used to treat susceptible strains of gram-negative bacteria, Neisseria gonorrhoeae. It is used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. Spectinomycin is an inhibitor of protein synthesis in the bacterial cell by binding to the 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Karxena Harford Created On: May 10, 2021 at 10:23 Last Updated: May 10, 2021 at 10:23
PW132419 View Pathway	metabolic Spectinomycin Drug Metabolism Homo sapiens Spectinomycin is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Spectinomycin passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 21:37 Last Updated: September 21, 2023 at 21:37
PW145020 View Pathway	drug action Spectinomycin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:56 Last Updated: October 07, 2023 at 14:56
PW088232 View Pathway	metabolic Spermidine and Spermine Biosynthesis Bos taurus The Spermidine and Spermine Biosynthesis pathway highlights the creation of these cruicial polyamines. Spermidine and spermine are produced in many tissues, as they are involved in the regulation of genetic processes from DNA synthesis to cell migration, proliferation, differentiation and apoptosis. These positiviely charged amines interact with negatively charged phosphates in nucleic acids to exert their regulatory effects on cellular processes. Spermidine originates from the action of spermidine synthase, which converts the methionine derivative S-adenosylmethionine and the ornithine derivative putrescine into spermidine 5'-methylthioadenosine. Spermidine is subsequently processed into spermine by spermine synthase in the presence of the aminopropyl donor, S-adenosylmethioninamine. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 10, 2018 at 11:29 Last Updated: August 10, 2018 at 11:29
PW088461 View Pathway	metabolic Spermidine and Spermine Biosynthesis Caenorhabditis elegans The Spermidine and Spermine Biosynthesis pathway highlights the creation of these cruicial polyamines. Spermidine and spermine are produced in many tissues, as they are involved in the regulation of genetic processes from DNA synthesis to cell migration, proliferation, differentiation and apoptosis. These positiviely charged amines interact with negatively charged phosphates in nucleic acids to exert their regulatory effects on cellular processes. Spermidine originates from the action of spermidine synthase, which converts the methionine derivative S-adenosylmethionine and the ornithine derivative putrescine into spermidine 5'-methylthioadenosine. Spermidine is subsequently processed into spermine by spermine synthase in the presence of the aminopropyl donor, S-adenosylmethioninamine. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 10, 2018 at 17:07 Last Updated: August 10, 2018 at 17:07