PathWhiz

PathWhiz ID	Pathway	Meta Data
PW145376 View Pathway	drug action Cefonicid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:41 Last Updated: October 07, 2023 at 15:41
PW175993 View Pathway	metabolic Cefonicid Predicted Metabolism Pathway new Homo sapiens Metabolites of Cefonicid are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 13:04 Last Updated: November 29, 2023 at 13:04
PW176944 View Pathway	drug action Cefoperazone Action Pathway Escherichia coli Cefoperazone is a broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, including the respiratory tract, abdomen, skin, and female genital tracts. Cefoperazone exhibits a bactericidal mode of action. It works by binding to and inhibiting bacterial penicillin-binding proteins (PBPs). Upon binding to PBPs, ertapenem inhibits bacterial cell wall synthesis by interfering with the lengthening and strengthening of the peptidoglycan portion of the cell wall, thereby inhibiting cell wall synthesis. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Karxena Harford Created On: January 02, 2024 at 09:18 Last Updated: January 02, 2024 at 09:18
PW145377 View Pathway	drug action Cefoperazone Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:42 Last Updated: October 07, 2023 at 15:42
PW175994 View Pathway	metabolic Cefoperazone Predicted Metabolism Pathway new Homo sapiens Metabolites of Cefoperazone are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 13:05 Last Updated: November 29, 2023 at 13:05
PW176958 View Pathway	drug action Ceforanide Action Pathway Escherichia coli Ceforanide is a 1-β methyl-carbapenem that is structurally related to beta-lactam antibiotics.5 It was first authorized for use in the US in November 2001 and in Europe in April 2002. Shown to be effective against a wide range of Gram-positive and Gram-negative aerobic and anaerobic bacteria, ertapenem is used to treat various bacterial infections. Ceforanide exhibits a bactericidal mode of action. It works by binding to and inhibiting bacterial penicillin-binding proteins (PBPs).5 In Escherichia coli, it has a strong affinity toward PBPs 1a, 1b, 2, 3, 4 and 5 with preferential binding to PBPs 2 and 3.5 Upon binding to PBPs, ertapenem inhibits bacterial cell wall synthesis by interfering with the lengthening and strengthening of the peptidoglycan portion of the cell wall, thereby inhibiting cell wall synthesis. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Karxena Harford Created On: January 02, 2024 at 09:20 Last Updated: January 02, 2024 at 09:20
PW145024 View Pathway	drug action Ceforanide Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:56 Last Updated: October 07, 2023 at 14:56
PW175995 View Pathway	metabolic Ceforanide Predicted Metabolism Pathway new Homo sapiens Metabolites of Ceforanide are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: November 29, 2023 at 13:05 Last Updated: November 29, 2023 at 13:05
PW126769 View Pathway	drug action Cefotaxime Action Pathway Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Cefotaxime is a third-generation cephalosporin used to treat susceptible gram-negative and gram-positive bacterial infections. It is used to treat gonorrhea, meningitis, and severe infections including infections of the kidney (pyelonephritis) and urinary system. Also used before an operation to prevent infection after surgery. action The bactericidal activity of cefotaxime results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Penicillin binding proteins are responsible for glycosyltransferase and transpeptidase reactions that lead to cross-linking of D-alanine and D-aspartic acid in bacterial cell walls. Inhibition of this protein leads to upregulation of autolytic enzymes and inhibition of cell wall synthesis. Cefotaxime is bactericidal and kills off the bacteria that it affects. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Karxena Harford Created On: March 23, 2022 at 03:06 Last Updated: March 23, 2022 at 03:06
PW144615 View Pathway	drug action Cefotaxime Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:02 Last Updated: October 07, 2023 at 14:02