PathWhiz

PathWhiz ID	Pathway	Meta Data
PW001886 View Pathway	metabolic L-glutamate metabolism II Escherichia coli BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: September 09, 2015 at 16:00 Last Updated: September 09, 2015 at 16:00
PW144273 View Pathway	drug action L-Glutamine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:04 Last Updated: October 07, 2023 at 13:04
PW122497 View Pathway	metabolic L-Homomethionine Biosynthesis Arabidopsis thaliana A non-protein amino acid and a derivative of methionine, homomethionine is synthesized through the process of chain elongation. In Arabidopsis thaliana and other members of the Cruciferae (Brassicaceae) family, it is synthesized as part of a multi-step pathway to generate glucosinolates. Glucosinolates are likely employed as a defense mechanism and are believed to be responsible for the pungent odour and taste associated with this plant family. The process starts in the cytosol of the plant cell with l-methionine as the primary substrate before moving into the chloroplast as 2-oxo-4-methylthiobutanoic acid. In the chloroplast, 3-isopropylmalate dehydratase plays a noteworthy role in catalyzing multiple reactions in the final synthesis of L-homomethionine. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Chris Created On: May 06, 2019 at 10:58 Last Updated: May 06, 2019 at 10:58
PW123553 View Pathway	metabolic L-Lactaldehyde Degradation (Aerobic) Pseudomonas aeruginosa (S)-lactaldehyde is derived from degradation of L-fucose and rhamnose. (S)-lactaldehyde is converted to lactic acid by lactaldehyde dehydrogenase with NAD as cofactor. L-lactate dehydrogenase dehydrogenates lactic acid to pyruvic acid for the pathway of glycolysis and pyruvate dehydrogenase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 12, 2019 at 22:31 Last Updated: August 12, 2019 at 22:31
PW002073 View Pathway	metabolic L-Lactaldehyde Degradation (Aerobic) Escherichia coli (S)-lactaldehyde is derived from degradation of L-fucose and rhamnose. (S)-lactaldehyde is converted to lactic acid by lactaldehyde dehydrogenase with NAD as cofactor. L-lactate dehydrogenase dehydrogenates lactic acid to pyruvic acid for the pathway of glycolysis and pyruvate dehydrogenase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 09, 2015 at 17:28 Last Updated: October 09, 2015 at 17:28
PW146803 View Pathway	drug action L-Lactic acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 19:04 Last Updated: October 07, 2023 at 19:04
PW273431 View Pathway	metabolic L-Leucine degradation Streptomyces avermitilis Leucine degradation is a key metabolic process that converts the essential amino acid leucine into energy and intermediate molecules used in various biosynthetic pathways.This pathway includes several enzymatic steps that ultimately transform leucine into acetyl-CoA and acetoacetate, both of which are crucial for the tricarboxylic acid (TCA) cycle and fatty acid synthesis. These reactions not only contribute to the organism's energy production but also provide necessary building blocks for the synthesis of vital compounds. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: June 11, 2024 at 16:24 Last Updated: June 11, 2024 at 16:24
PW002100 View Pathway	metabolic L-Lyxose Degradation Escherichia coli L-lyxose is a sugar and a monosaccharide containing five carbon atoms and aldehyde group. Wild-type E.coli can't utilize L-lyxose as its source of carbon and energy. In mutated E.coli, it can metabolize l-lyxose through utilization of enzymes of the rhamnose, arabinose and 2,3-diketo-L-gulonate systems. β-L-lyxopyranose enter cell by L-rhamnose-proton symporter, then convert to l-xylulose by L-rhamnose isomerase. L-xylulose is further metabolized to L-xylulose-5-phosphate with energy ATP. Putative L-ribulose-5-phosphate 3-epimerase can convert L-xylulose -5-phosphate to L-ribulose 5-phosphate, and L-ribulose 5-phosphate 4-epimerase can catalyze L-ribulose 5-phosphate to xylulose 5-phosphate for further pentose phosphate. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 14, 2015 at 09:50 Last Updated: October 14, 2015 at 09:50
PW002106 View Pathway	metabolic L-Threonine Degradation to Methylglyoxal Escherichia coli L-threonine is degrade into methylglyoxal (pyruvaldehyde) by first reacting with a NDA dependent threonine dehydrogenase resulting in the release of a hydrogen ion, an NADH and a 2-amino-3-oxobutanoate. The latter compound reacts spontaneously with a hydrogen ion resulting in the release of a carbon dioxide and a aminoacetone. The aminoacetone in turn reacts with an oxygen and a water molecule through an aminoacetone oxidase resulting in the release of a hydrogen peroxide, ammonium and a methylglyoxal which can then be incorporated in the methylglyoxal degradation pathways. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: October 14, 2015 at 11:23 Last Updated: October 14, 2015 at 11:23
PW146974 View Pathway	metabolic L-Threonine Drug Metabolism Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 10, 2023 at 13:33 Last Updated: October 10, 2023 at 13:33