PathWhiz

PathWhiz ID	Pathway	Meta Data
PW144684 View Pathway	drug action Cephalexin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:13 Last Updated: October 07, 2023 at 14:13
PW176326 View Pathway	metabolic Cephalexin Predicted Metabolism Pathway Homo sapiens Metabolites of sildenafil are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: December 07, 2023 at 15:07 Last Updated: December 07, 2023 at 15:07
PW176955 View Pathway	drug action Cephaloglycin Action Pathway Escherichia coli Cephaloglycin is a cephalorsporin antibiotic that is no longer commonly used. Cephaloglycin exhibits an anti-bacterial mechanism of action. It works by binding to and inhibiting bacterial penicillin-binding proteins (PBPs). Upon binding to PBPs, ertapenem inhibits bacterial cell wall synthesis by interfering with the lengthening and strengthening of the peptidoglycan portion of the cell wall, thereby inhibiting cell wall synthesis. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Karxena Harford Created On: January 02, 2024 at 09:19 Last Updated: January 02, 2024 at 09:19
PW144801 View Pathway	drug action Cephaloglycin Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 14:27 Last Updated: October 07, 2023 at 14:27
PW121714 View Pathway	disease Cerebrotendinous Xanthomatosis (CTX) Mus musculus Cerebrotendinous Xanthomatosis, also called CTX, is a rare inborn error of metabolism (IEM) which results from a genetic mutation. More specifically, it is the result of a mutated CYP27A1 gene. This said gene is responsible for encoding sterol 27-hydroxylase. The importance of this enzyme if the following, the said enzyme is responsible for the catalysis during the oxidation of several compounds. In particular, the said enzyme interacts with sterol intermediates, and 7-alpha,12-alpha-triol, among others. CTX is rare and can be thought of as an inherited lipid-storage disease. It causes the widespread deposition of two main compounds (cholesterol and cholestanol) throughout essentially every single tissue in the body. Including, the brain and lungs, to the detriment of the affected. Symptoms of CTX are neurological dysfunction, premature atherosclerosis, and cataracts. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:49 Last Updated: September 10, 2018 at 15:49
PW127263 View Pathway	disease Cerebrotendinous Xanthomatosis (CTX) Homo sapiens Cerebrotendinous Xanthomatosis, also called CTX or 27-Hydroxylase Deficiency, is a rare inborn error of metabolism (IEM) which results from a genetic mutation. More specifically, it is the result of a mutated CYP27A1 gene. This said gene is responsible for encoding sterol 27-hydroxylase. The importance of this enzyme if the following, the said enzyme is responsible for the catalysis during the oxidation of several compounds. In particular, the said enzyme interacts with sterol intermediates, and 7-alpha,12-alpha-triol, among others. CTX is characterized by the accumulation of cholestanol and cholesterol due to the inability to break down the lipids. CTX is rare and can be thought of as an inherited lipid-storage disease. It causes the widespread deposition of two main compounds (cholesterol and cholestanol) throughout essentially every single tissue in the body. Including, the brain and lungs, to the detriment of the affected. Symptoms of CTX are neurological dysfunction (such as dementia), premature atherosclerosis, and cataracts. Other symptoms may include damaged liver cells and body tissues. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: November 24, 2022 at 12:43 Last Updated: November 24, 2022 at 12:43
PW000196 View Pathway	disease Cerebrotendinous Xanthomatosis (CTX) Homo sapiens Cerebrotendinous Xanthomatosis, also called CTX, is a rare inborn error of metabolism (IEM) which results from a genetic mutation. More specifically, it is the result of a mutated CYP27A1 gene. This said gene is responsible for encoding sterol 27-hydroxylase. The importance of this enzyme if the following, the said enzyme is responsible for the catalysis during the oxidation of several compounds. In particular, the said enzyme interacts with sterol intermediates, and 7-alpha,12-alpha-triol, among others. CTX is rare and can be thought of as an inherited lipid-storage disease. It causes the widespread deposition of two main compounds (cholesterol and cholestanol) throughout essentially every single tissue in the body. Including, the brain and lungs, to the detriment of the affected. Symptoms of CTX are neurological dysfunction, premature atherosclerosis, and cataracts. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: August 19, 2013 at 12:05 Last Updated: August 19, 2013 at 12:05
PW121939 View Pathway	disease Cerebrotendinous Xanthomatosis (CTX) Rattus norvegicus Cerebrotendinous Xanthomatosis, also called CTX, is a rare inborn error of metabolism (IEM) which results from a genetic mutation. More specifically, it is the result of a mutated CYP27A1 gene. This said gene is responsible for encoding sterol 27-hydroxylase. The importance of this enzyme if the following, the said enzyme is responsible for the catalysis during the oxidation of several compounds. In particular, the said enzyme interacts with sterol intermediates, and 7-alpha,12-alpha-triol, among others. CTX is rare and can be thought of as an inherited lipid-storage disease. It causes the widespread deposition of two main compounds (cholesterol and cholestanol) throughout essentially every single tissue in the body. Including, the brain and lungs, to the detriment of the affected. Symptoms of CTX are neurological dysfunction, premature atherosclerosis, and cataracts. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: September 10, 2018 at 15:51 Last Updated: September 10, 2018 at 15:51
PW132575 View Pathway	metabolic Ceritinib Drug Metabolism Homo sapiens Ceritinib is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Ceritinib passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 22:28 Last Updated: September 21, 2023 at 22:28
PW145946 View Pathway	drug action Ceritinib Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:02 Last Updated: October 07, 2023 at 17:02