PathWhiz

PathWhiz ID	Pathway	Meta Data
PW685855 View Pathway	metabolic Chitobiose Degradation Acidaminococcus intestini RyC-MR95 Diacetylchitobiose (also known as N,N'-diacetylchitobiose and chitobiose) is a sole source of carbon for E.coli. PTS system mannitol-specific EIICBA component facilitates the imports of diacetylchitobiose as well as the phosphorylation to diacetylchitobiose 6'-phosphate. Later on, diacetylchitobiose 6'-phosphate is hydrolyzed to N-monoacetylchitobiose 6'-phosphate, which also produce acetic acid. N-monoacetylchitobiose 6'-phosphate undergoes further hydrolyzation to form N-Acetyl-D-Glucosamine 6-Phosphate and glucosamine by monoacetylchitobiose-6-phosphate hydrolase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: January 30, 2025 at 20:20 Last Updated: January 30, 2025 at 20:20
PW490705 View Pathway	metabolic Chitobiose Degradation Bacteroides eggerthii 1_2_48FAA Diacetylchitobiose (also known as N,N'-diacetylchitobiose and chitobiose) is a sole source of carbon for E.coli. PTS system mannitol-specific EIICBA component facilitates the imports of diacetylchitobiose as well as the phosphorylation to diacetylchitobiose 6'-phosphate. Later on, diacetylchitobiose 6'-phosphate is hydrolyzed to N-monoacetylchitobiose 6'-phosphate, which also produce acetic acid. N-monoacetylchitobiose 6'-phosphate undergoes further hydrolyzation to form N-Acetyl-D-Glucosamine 6-Phosphate and glucosamine by monoacetylchitobiose-6-phosphate hydrolase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: January 31, 2025 at 13:54 Last Updated: January 31, 2025 at 13:54
PW507598 View Pathway	metabolic Chitobiose Degradation Bacteroides plebeius Diacetylchitobiose (also known as N,N'-diacetylchitobiose and chitobiose) is a sole source of carbon for E.coli. PTS system mannitol-specific EIICBA component facilitates the imports of diacetylchitobiose as well as the phosphorylation to diacetylchitobiose 6'-phosphate. Later on, diacetylchitobiose 6'-phosphate is hydrolyzed to N-monoacetylchitobiose 6'-phosphate, which also produce acetic acid. N-monoacetylchitobiose 6'-phosphate undergoes further hydrolyzation to form N-Acetyl-D-Glucosamine 6-Phosphate and glucosamine by monoacetylchitobiose-6-phosphate hydrolase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 08, 2025 at 18:11 Last Updated: February 08, 2025 at 18:11
PW685860 View Pathway	metabolic Chitobiose Degradation Bacteroides thetaiotaomicron VPI-5482 Diacetylchitobiose (also known as N,N'-diacetylchitobiose and chitobiose) is a sole source of carbon for E.coli. PTS system mannitol-specific EIICBA component facilitates the imports of diacetylchitobiose as well as the phosphorylation to diacetylchitobiose 6'-phosphate. Later on, diacetylchitobiose 6'-phosphate is hydrolyzed to N-monoacetylchitobiose 6'-phosphate, which also produce acetic acid. N-monoacetylchitobiose 6'-phosphate undergoes further hydrolyzation to form N-Acetyl-D-Glucosamine 6-Phosphate and glucosamine by monoacetylchitobiose-6-phosphate hydrolase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: January 30, 2025 at 21:59 Last Updated: January 30, 2025 at 21:59
PW508762 View Pathway	metabolic Chitobiose Degradation Escherichia coli O127:H6 str. E2348/69 Diacetylchitobiose (also known as N,N'-diacetylchitobiose and chitobiose) is a sole source of carbon for E.coli. PTS system mannitol-specific EIICBA component facilitates the imports of diacetylchitobiose as well as the phosphorylation to diacetylchitobiose 6'-phosphate. Later on, diacetylchitobiose 6'-phosphate is hydrolyzed to N-monoacetylchitobiose 6'-phosphate, which also produce acetic acid. N-monoacetylchitobiose 6'-phosphate undergoes further hydrolyzation to form N-Acetyl-D-Glucosamine 6-Phosphate and glucosamine by monoacetylchitobiose-6-phosphate hydrolase. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Julia Wakoli Created On: February 08, 2025 at 23:52 Last Updated: February 08, 2025 at 23:52
PW147038 View Pathway	metabolic Chlophedianol Drug Metabolism Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 10, 2023 at 13:42 Last Updated: October 10, 2023 at 13:42
PW145445 View Pathway	drug action Chloral hydrate Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:50 Last Updated: October 07, 2023 at 15:50
PW128198 View Pathway	drug action Chlorambucil Action Pathway Homo sapiens Chlorambucil is an antineoplastic agent from the nitrogen mustard alkylating class. It is indicated in the treatment of chronic lymphatic leukemia, lymphosarcoma, giant follicular lymphoma, Hodgkin's disease, non-Hodgkin's lymphoma, and Waldenström’s macroglobulinemia. This class of agents is named like that for their ability to add alkyl groups to many electronegative groups. They work by three different mechanisms all of which achieve the same result: death of the cancerous cell. The first mechanism of action is to attach alkyl groups to DNA bases. This causes the fragmentation of the DNA by repair enzymes. Secondly, the alkylating agents cause damage to DNA via the formation of cross-links. The cross-links prevent the DNA from being separated for synthesis or transcription. The third mechanism of action is the induction of mispairing of the bases, leading to many mutations. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Daphnee Created On: August 01, 2023 at 12:52 Last Updated: August 01, 2023 at 12:52
PW144419 View Pathway	drug action Chlorambucil Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:36 Last Updated: October 07, 2023 at 13:36
PW000706 View Pathway	drug action Chloramphenicol Action Pathway Homo sapiens Chloramphenicol, trade names Pentamycetin and Chloromycetin, is a broad spectrum antibiotic originally derived from Streptomyces venezuelae. It inhibits protein synthesis by binding the 50S ribosomal subunit to prevent bacterial growth. Bacterial resistance has occurred through decreased uptake or permeability, ribosomal mutation and inactivation by acetylation. Adverse side effects such as aplastic anemia, bone-marrow suppression or Gray syndrome in neonates and infants have resulted in limited use. However, due to ampicillin-resistance bacterial meningitis there has been a renewed interest in the drug. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: WishartLab Created On: June 23, 2014 at 03:57 Last Updated: June 23, 2014 at 03:57