PathWhiz

PathWhiz ID	Pathway	Meta Data
PW124077 View Pathway	drug action MyTest Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Guest: Anonymous Created On: August 13, 2020 at 15:48 Last Updated: August 13, 2020 at 15:48
PW146788 View Pathway	drug action N,N'-diphenyl-1,4-phenylenediamine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 19:02 Last Updated: October 07, 2023 at 19:02
PW144283 View Pathway	drug action N-Acetylglucosamine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 13:06 Last Updated: October 07, 2023 at 13:06
PW002030 View Pathway	metabolic N-Acetylneuraminate, N-Acetylmannosamine, and N-Acetylglucosamine Degradation Escherichia coli The degradation of N-acetylneuraminate begins with its incorporation into the cytosol through a hydrogen symporter. Once inside the cytosol it is degraded by a N-acetylneuraminate lyase resulting in a release of a pyruvic acid and N-acetymannosamine. The latter compound is phosphorylated by an ATP driven N-Acetylmannosamine kinase resulting in the release of an ADP, a hydrogen ion and a N-Acetyl-D-mannosamine 6-phosphate. This phosphorylated compound is then metabolized by a putative N-acetylmannosamine-6-phosphate 2-epimerase resulting in the release of a N-Acetyl-D-glucosamine 6-phosphate. This compound is then deacetylated through a N-acetylglucosamine-6-phosphate deacetylase resulting in the release of an Acetic acid and a glucosamine 6-phosphate This compound can then be deaminated through a glucosamine-6-phosphate deaminase resulting in the release of an ammonium and a beta-D-fructofuranose 6-phosphate which can then be incorporated into the glycolysis pathway. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: October 06, 2015 at 13:35 Last Updated: October 06, 2015 at 13:35
PW146233 View Pathway	drug action N-acetyltyrosine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:44 Last Updated: October 07, 2023 at 17:44
PW146295 View Pathway	drug action N-alkyl ethylbenzyl dimethyl ammonium (C12-C14) Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:53 Last Updated: October 07, 2023 at 17:53
PW146792 View Pathway	drug action N-Cyclohexyl-N'-phenyl-1,4-phenylenediamine Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 19:03 Last Updated: October 07, 2023 at 19:03
PW002501 View Pathway	metabolic N-Glycan Biosynthesis Saccharomyces cerevisiae The N-glycan biosynthesis is a pathway involving the creation of a dolichol, and the consecutive reactions involving the addition of Acetylglucosaminyl groups, mannosyl groups and glucosyl groups. The set of reactions all happen in the ER membrane. The resulting glucosyl3mannosyl9-N-acetylglucosaminyl2-diphosphodolichol is used as protein modificator. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: March 08, 2016 at 15:06 Last Updated: March 08, 2016 at 15:06
PW001889 View Pathway	metabolic N-Oxide Electron Transfer Escherichia coli The pathway can start in various spots. First step in this case starts with NADH interacting with a menaquinone oxidoreductase resulting in the release of a NADH and a hydrogen Ion, at the same time in the inner membrane a menaquinone interacts with 2 electrons and 2 hydrogen ions thus releasing a menaquinol. This allows for 4 hydrogen ions to be transferred from the cytosol to the periplasmic space. The menaquinol then interacts with a trimethylamine N-oxide reductase resulting in the release of 2 hydrogen ion and 2 electrons. At the same time trimethylamine N-oxide and 3 hydrogen ions interact with the enzyme trimethylamine N-oxide reductase resulting in the release of a trimethylamine and a water molecule, this reaction happening in the periplasmic space. The second set of reactions starts with a hydrogen interacting with a menaquinone oxidoreductase resulting in the release of two electrons being released into the inner membrane which then react with with 2 hydrogen ion and a menaquinone to produce a menaquinol. This menaquinol then reacts with a trimethylamine N-oxide reductase following the same steps as mentioned before. The third set of reactions starts with with formate interacting with a formate dehydrogenase-O resulting in a release of carbon dioxide and a hydrogen ion, this releases 2 electrons that interact with a menaquinone and two hydrogen ions. This releases a menaquinol which then reacts with a trimethylamine N-oxide reductase following the same steps as mentioned before BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: miguel ramirez Created On: September 09, 2015 at 18:13 Last Updated: September 09, 2015 at 18:13
PW123409 View Pathway	metabolic N-Oxide Electron Transfer Pseudomonas aeruginosa The pathway can start in various spots. First step in this case starts with NADH interacting with a menaquinone oxidoreductase resulting in the release of a NADH and a hydrogen Ion, at the same time in the inner membrane a menaquinone interacts with 2 electrons and 2 hydrogen ions thus releasing a menaquinol. This allows for 4 hydrogen ions to be transferred from the cytosol to the periplasmic space. The menaquinol then interacts with a trimethylamine N-oxide reductase resulting in the release of 2 hydrogen ion and 2 electrons. At the same time trimethylamine N-oxide and 3 hydrogen ions interact with the enzyme trimethylamine N-oxide reductase resulting in the release of a trimethylamine and a water molecule, this reaction happening in the periplasmic space. The second set of reactions starts with a hydrogen interacting with a menaquinone oxidoreductase resulting in the release of two electrons being released into the inner membrane which then react with with 2 hydrogen ion and a menaquinone to produce a menaquinol. This menaquinol then reacts with a trimethylamine N-oxide reductase following the same steps as mentioned before. The third set of reactions starts with with formate interacting with a formate dehydrogenase-O resulting in a release of carbon dioxide and a hydrogen ion, this releases 2 electrons that interact with a menaquinone and two hydrogen ions. This releases a menaquinol which then reacts with a trimethylamine N-oxide reductase following the same steps as mentioned before BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 12, 2019 at 21:53 Last Updated: August 12, 2019 at 21:53