Loader

Pathways

PathWhiz ID Pathway Meta Data

PW146147

Pw146147 View Pathway
drug action

Potassium perchlorate Drug Metabolism Action Pathway

Homo sapiens

PW146821

Pw146821 View Pathway
drug action

Potassium sulfate Drug Metabolism Action Pathway

Homo sapiens

PW147048

Pw147048 View Pathway
metabolic

Povidone Drug Metabolism Pathway

Homo sapiens

PW146806

Pw146806 View Pathway
drug action

Povidone K30 Drug Metabolism Action Pathway

Homo sapiens

PW145813

Pw145813 View Pathway
drug action

Povidone-iodine Drug Metabolism Action Pathway

Homo sapiens

PW123679

Pw123679 View Pathway
signaling

ppar

Rattus norvegicus

PW123974

Pw123974 View Pathway
metabolic

PQS Biosynthesis

Pseudomonas aeruginosa

PW126832

Pw126832 View Pathway
metabolic

pr1

Homo sapiens

PW012846

Pw012846 View Pathway
disease

Practices

Arabidopsis thaliana

PW000646

Pw000646 View Pathway
drug action

Practolol Action Pathway

Homo sapiens
Practolol (also known as Eraldin or Dalzic) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Practolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of other adrenergic neurotransmitters such as norepinephrine, which lead to decreased blood pressure, heart rate and cardiac output. Practolol can also bind beta-2 adrenergic receptors in juxtaglomerular apparatus and bronchiole smooth muscle. In juxtaglomerular apparatus, practolol can prevent the production of aldosterone and angiotensin II by inhibiting renin production, which lead to prevention of water retention and vasoconstriction. In bronchiole smooth muscle, binding of practolol to beta-2 adrenergic receptors can also prevent vasoconstriction.