PathWhiz

PathWhiz ID	Pathway	Meta Data
PW123546 View Pathway	metabolic Thiosulfate Disproportionation III Pseudomonas aeruginosa Thiosulfate sulfurtransferase (also known as rhodanese) can facilitate the transfer of a sulfur atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: August 12, 2019 at 22:30 Last Updated: August 12, 2019 at 22:30
PW002060 View Pathway	metabolic Thiosulfate Disproportionation III Escherichia coli Thiosulfate sulfurtransferase (also known as rhodanese) can facilitate the transfer of a sulfur atom from sulfur donors to nucleophilic sulfur acceptors, and it has been found in many major phyla (prokaryotic and eukaryotic). The role of thiosulfate sulfurtransferase might be the detoxification of cyanide in both bacteria and mammals, or it might also involve in formation of prosthetic groups in iron-sulfur proteins. In this pathway, thiosulfate and hydrogen cyanide have been catalyzed by thiosulfate sulfurtransferase to form thiocyanate and sulfite. Sulfite is used in later sulfur metabolism. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ana Marcu Created On: October 09, 2015 at 09:50 Last Updated: October 09, 2015 at 09:50
PW146175 View Pathway	drug action Thiosulfuric acid Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:35 Last Updated: October 07, 2023 at 17:35
PW132352 View Pathway	metabolic Thiotepa Drug Metabolism Homo sapiens Thiotepa is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Thiotepa passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 21:07 Last Updated: September 21, 2023 at 21:07
PW145563 View Pathway	drug action Thiotepa Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 16:05 Last Updated: October 07, 2023 at 16:05
PW128181 View Pathway	drug action Thiothixene Dopamine Antagonist Action Pathway Homo sapiens Thiothixene is an antipsychotic of the thioxanthene series. Thiothixene acts as an antagonist (blocking agent) on different post-sysnaptic receptors -on dopaminergic-receptors (subtypes D1, D2, D3 and D4 - different antipsychotic properties on productive and unproductive symptoms), on serotonergic-receptors (5-HT1 and 5-HT2, with anxiolytic, antidepressive and antiaggressive properties as well as an attenuation of extrapypramidal side-effects, but also leading to weight gain, fall in blood pressure, sedation and ejaculation difficulties), on histaminergic-receptors (H1-receptors, sedation, antiemesis, vertigo, fall in blood pressure and weight gain), alpha1/alpha2-receptors (antisympathomimetic properties, lowering of blood pressure, reflex tachycardia, vertigo, sedation, hypersalivation and incontinence as well as sexual dysfunction, but may also attenuate pseudoparkinsonism - controversial) and finally on muscarinic (cholinergic) M1/M2-receptors (causing anticholinergic symptoms like dry mouth, blurred vision, obstipation, difficulty/inability to urinate, sinus tachycardia, ECG-changes and loss of memory, but the anticholinergic action may attenuate extrapyramidal side-effects) BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Omolola Created On: July 28, 2023 at 12:17 Last Updated: July 28, 2023 at 12:17
PW145486 View Pathway	drug action Thiothixene Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 15:55 Last Updated: October 07, 2023 at 15:55
PW132294 View Pathway	metabolic Thiram Drug Metabolism Homo sapiens Thiram is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Thiram passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: September 21, 2023 at 20:41 Last Updated: September 21, 2023 at 20:41
PW146617 View Pathway	drug action Thiram Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 18:38 Last Updated: October 07, 2023 at 18:38
PW146196 View Pathway	drug action Thonzonium Drug Metabolism Action Pathway Homo sapiens BioPAX SVG SBGN SBML PWML All files (.zip)	Creator: Ray Kruger Created On: October 07, 2023 at 17:38 Last Updated: October 07, 2023 at 17:38